При варикозном расширении вен не обойтись без приема внутрь препаратов тонизирующих вены. Популярностью пользуются такие средства как Венарус или Детралекс. Отзывы врачей и пациентов о них – самые лучшие.
Интерес заболевших варикозом вызывает и сравнительно новый препарат Флебодиа 600. Какими они обладают свойствами, какой из них лучше, а также что думают врачи и пациенты – читайте в этой статье.
Состав и содержание активного вещества
Все три описанных в статье препарата содержат аналогичные компоненты и, соответственно, обладают похожим эффектом. Ниже разберем каждый из них подробнее.
Венарус
Венарус – отечественный препарат, выпускается в форме таблеток для внутреннего применения. Особенность таблеток в их оболочке – она растворяется только в кишечнике, а не в желудке, что обеспечивает быстрое и полное всасывание и усвоение.
В состав препарата входят два активных вещества: диосмин 450 мг и гесперидин 50 мг. Благодаря им достигается следующий эффект:
- происходит укрепление стенок сосудистой и лимфатической систем за счет коллагена;
- укрепляются не только крупные вены, но и мелкая сосудистая сетка;
- лучше начинают работать клапаны в венах, благодаря чему улучшается кровоток и уменьшается риск растягивания сосудов;
- кровь и лимфа начинают лучше циркулировать, уменьшая застойные явления.
Существенный плюс препарата Венарус – отсутствие противопоказаний при беременности. Во время вынашивания плода у женщин часто ухудшается состояние вен и сосудов, возникают варикоз и геморрой. Поэтому им особенно нужны поддерживающие препараты.
Кроме того, Венарус можно применять не только для лечения, но и для профилактики. Выпускается он и в виде геля для наружного применения для комплексной терапии заболевания.
Важно! Сочетание геля и таблеток в комплексе оказывает более быстрый лечебный эффект, особенно эффективно в запущенных случаях и при обострении.
Детралекс
Детралекс содержит то же, что и Венарус: диосмин 450 мг и гесперидин 50 мг. Тогда возникает вопрос: в чем разница? А разница в производителе. Венарус – отечественное средство, а Детралекс выпускается во Франции.
Но не только. Иностранный препарат производится по особой технологии. Благодаря ей активные компоненты находятся в форме, позволяющей им быстрее проникать в кровь. А значит, лекарственный эффект наступает быстрее.
Вот какими свойствами обладает Детралекс:
- уплотнение стенок вен;
- повышение упругости сосудов;
- укрепление венозных клапанов;
- устранение растяжения сосудов;
- нормализация кровотока;
- нормализация микроциркуляции;
- снижение хрупкости и проницаемости сосудов;
- устранение застойных явлений.
В целом – повышается тонус вен и сосудов, улучшаются процессы восстановления тканей. При геморрое уменьшаются кровотечения. Как и Венарус, Детралекс можно применять во время беременности.
Важно! Исследований по поводу попадания препарата в грудное молоко не проводилось, поэтому принимать его во время кормления грудью следует с осторожностью и при любых тревожных симптомах прием прекратить.
Флебодиа
Флебодиа 600 – новый препарат на рынке, он широко рекламируется, а потому вызывает интерес у больных варикозным расширением. Чем он отличается от других препаратов? Как и у Детралекса – производство Франция. Выпускается в виде таблеток. Но Флебодиа – препарат, в который входит только одно активное вещество: 600 мг диосмина.
Активное вещество распределяется избирательно, то есть действует преимущественно там, где это и требуется. Вот какое действие оказывает Флебодиа 600:
повышение тонуса стенок сосудов;- устранение растяжения сосудов;
- обезболивающий и противовоспалительный эффект;
- уменьшение хрупкости и проницаемости сосудов;
- улучшение микроциркуляции;
- устранение застойных явлений;
- улучшение лимфотока;
- снятие отеков;
- предупреждение образования трофических язв.
повышение тонуса стенок сосудов;Препарат можно применять во время беременности, однако досконально процесс влияния на плод еще не изучен.
Сравнительный анализ
Итак, попробуем сравнить, что эффективнее при лечении варикозного расширения вен. Венарус и Детралекс содержат один и тот же активный компонент. Отличие – в его форме. Поэтому и действие немного отличается.
Так, Детралекс быстрее всасывается в кровь, а значит, лечебный эффект тоже наступает быстрее, чем у Венаруса. Чтобы последний подействовал в полной мере, придется подождать. Зато, благодаря отечественному производству, стоимость Венаруса значительно ниже, чем у его французского аналога.
В остальном же эти два препарата можно считать равнозначными и взаимозаменяемыми. Поэтому, что лучше – Детралекс или Венарус при варикозе, каждый больной решает сам для себя.
Что касается Флебодиа 600, то он содержит только один активный компонент против двух у Венаруса и Детралекса. А значит, того действия, что оказывает отсутствующее в нем вещество, он не окажет. Принимать Флебодиа проще – достаточно одной таблетки в день, поскольку дольше длится период распада. Из-за кратности приема суточная доза активного вещества будет меньше, чем в Венарусе или Детралексе.
Что касается стоимости, то Флебодиа дороже российского препарата, однако полный курс лечения последним в конечном итоге будет стоить выше.
Мнение врачей
Воробьева И.В., хирург, г. Москва: «Детралекс мне нравится тем, что при его применении терапевтический эффект достигается максимально быстро. Это особенно хорошо при обострении заболевания, при выраженном болевом эффекте. Также быстро спадают отеки, уменьшается дискомфорт при нагрузках. Назначаю его своим пациентам.»
Кузнецов О.П., терапевт, г. Нижневартовск: «Не вижу принципиальной разницы между препаратами Венарус и Детралекс. Действуют они одинаково. А что касается более быстрого эффекта от французского средства, то в любом случае этого недостаточно для полного курса. Лечение должно быть продолжительным и комплексным.»
Ивушкина М.К., сосудистый хирург, г. Екатеринбург: «Все три препарата зарекомендовали себя неплохо. Однако все они хороши только в составе комплексной терапии. Вылечить ими варикозное расширение нельзя, можно только облегчить состояние и устранить болезненные симптомы. А для запущенных стадий и вовсе показана лишь операция.»
Мнение пациентов
Ольга, 38 лет, г. Москва: «После рождения второго ребенка появился сильный варикоз. Пользовалась разными мазями сама, потом не выдержала и пошла к врачу. Он посоветовал Венарус. Теперь регулярно прохожу курс лечения и гелем тоже пользуюсь. Стало значительно лучше.»
Катерина, 49 лет, г. Курган: «С варикозом живу уже много лет, перепробовала много средств – как таблеток, так и мазей. Вздохнула с облегчением, только когда попробовала Флебодиа 600. Облегчение наступило быстро, сразу же стали спадать отеки и боли. Работаю я учителем – полдня на ногах, поэтому для меня это очень важно.»
Василий, 42 года, г. Ульяновск: «Врач прописал Детралекс. Отличный препарат, действует быстро, снимает все неприятные симптомы. Однажды его не было в аптеке, и фармацевт посоветовала Венарус, сказала, что это аналог. Попробовал – и перешел на него. Разницы вот вообще никакой, только стоит гораздо дешевле.»
Заключение
Каждый решает сам для себя, что ему лучше принимать: Детралекс, Флебодиа 600 или Венарус. Отзывы о них в сети можно найти разные, от положительных до резко отрицательных.
Однако в любом случае не стоит заниматься самолечением. Любой из препаратов стоит принимать только по рекомендации врача, а при малейших ухудшениях прием прекратить. Ведь халатное отношение к венам может привести к тромбофлебитам, трофическим язвам и даже летальному исходу.
Флебологи все чаще диагностируют у пациентов венозную недостаточность. Активный образ жизни, вредные привычки и длительный стресс не оставляют сосудам шансов остаться здоровыми.
Без правильного лечения проблема может привести к печальным последствиям – трофическим язвам, инфекционным поражениям, появлению тромбов, инвалидности больного.
Ситуация ухудшается тем, что патология развивается в течение нескольких лет, и поэтому требует длительного лечения.
Основную линию в терапии варикоза и венозной недостаточности занимают препараты группы венотоников. Одними из наиболее популярных считаются Венарус , Детралекс и Флебодиа. Многие пациенты не могут выбрать, что лучше при варикозе – Венарус или Флебодиа, поэтому ниже мы рассмотрим основные преимущества и отличия этих препаратов.
Что эффективнее при варикозе: Детралекс, Венарус или Флебодиа?
Навигация по статье
Лечение варикоза должно быть направлено на:
- Устранение первопричины и провоцирующего фактора.
- Укрепление венозных сосудов и повышение их устойчивости к действию неблагоприятных факторов.
Все препараты из группы венотоников могут влиять только на состояние венозной стенки, но не устраняют причину, которая привела к варикозному расширению. Таким образом, Детралекс, Венарус и Флебодиа имеют схожий механизм действия и одну мишень — вены. Сделать вывод о том, какое средство лучше помогает от варикоза, можно после изучения состава или собственного опыта применения этих лекарств.
Венарус или Флебодиа – что лучше при варикозе? Сравним препараты по основным пунктам инструкций к применению, а также захватим в обзор Детралекс, аналогом которого и является Венарус.
Лекарственная форма
Венарус выпускается в форме таблеток, покрытых оболочкой. Они имеют оранжево-розовый цвет и продолговатую форму.
Производитель лекарства – Россия. Венарус выпускается в упаковках с разным количеством таблеток (20-135 штук).
Препарат относится к группе венотоников комбинированного состава. Отпускается из аптек без рецепта.
Детралекс представляет собой овальные таблетки, покрытые оболочкой. Благодаря добавлению таких вспомогательных компонентов, как оксид железа красный и желтый, а также диоксид титана, таблетка имеет оранжево-розовый цвет.
Производитель – Франция. Детралекс, наряду с Флебодиа 600, считаются оригинальными препаратами-венотониками, по аналогии с которыми было выпущено большинство остальных. Доступны упаковки на 30 и 60 таблеток. Препарат относится к безрецептурному отпуску.
Флебодиа. Розовые таблетки, покрытые пленочной оболочкой. В упаковке находится 30 таблеток. Препарат производится во Франции, считается качественным и эффективным. Отпускается из аптек без рецепта.
Различия в составе
Венарус представляет собой комбинированный препарат, который содержит два активных компонента – 50 мг гесперидина и 450 мг диосмина.
Детралекс – оригинальный препарат с этой же комбинацией – 50 мг гесперидина и 450 мг диосмина.
Несмотря на то, что Флебодиа – аналог Детралекса при варикозе, этот препарат содержит только одно действующее вещество.
Из ее состава исключен гесперидин, а дозировка диосмина повышена и составляет 600 мг. По эффективности Флебодиа не уступает Детралексу и так же часто назначается медиками.
Что лучше принимать при варикозе – Детралекс или Венарус? Если препараты имеют одинаковый состав, пациент имеет право выбрать любой из них. Решающими моментами в этом случае становятся цена, схема приема, производитель и качество лекарства.
Фармацевтическое действие
Чтобы понять действие препаратов на организм, нужно разобраться в их действующих веществах.
Гесперидин. Это вещество растительного происхождения. Оно относится к группе флавоноидов.
При регулярном приеме способствует укреплению стенок сосудов и снижению и проницаемости. Благодаря этому повышается тонус вен, уменьшается выраженность варикоза и симптомы, которые беспокоят пациента.
Гесперидин положительно влияет на микроциркуляцию и лимфоотток.
Кроме этого, было выявлено антиоксидантное действие гесперидина, что очень важно для процесса обновления поврежденных тканей и сосудов. Замедляя процесс старения и разрушения клеток, гесперидин тормозит патологический процесс и дает возможность организму самому справиться с проблемой.
Таким образом, гесперидин оказывает ангиопротекторное действие, антиоксидантное и венотонизирующее.
Диосмин также относится к группе флавоноидов, но является полусинтетического происхождения. Используется для лечения заболеваний вен, в том числе геморроидальном расширении сосудов.
Клинические испытания показали, что это вещество эффективно на всех стадиях развития венозной недостаточности или варикоза. При регулярном использовании диосмина качество жизни пациента значительно улучшается.
Диосмин проявляет сосудосуживающее действие, сила которого зависит от принятой дозы. Кроме этого, вещество уменьшает застойные явления, повышает устойчивость капилляров к действию неблагоприятных факторов, уменьшает их проницаемость.
Диосмин положительно влияет на лимфатический дренаж благодаря способности увеличивать силу и частоту сокращений лимфатических сосудов.
При заболеваниях вен, которые сопровождаются воспалительным процессом, важным свойством диосмина является уменьшение лейкоцитов и медиаторов воспаления в очаге.
Оба вещества быстро всасываются в организм при пероральном приеме. Максимальные концентрации наблюдаются уже через несколько часов, а наибольшее количество фиксируется в области глубоких и подкожных вен нижних конечностей. Однако положительная клиническая динамика будет наблюдаться только через некоторое время, которое необходимо для восстановления структуры сосудов и рассасывания застоя.
Сфера применения
Флебодиа, Детралекс и Венарус используются при заболеваниях, в которых наблюдается нарушение оттока венозной крови. Эти препараты могут назначаться при:
- Венозной недостаточности.
- Варикозном расширении вен.
- Геморрое.
Кроме этого, венотоники могут назначаться врачами в качестве профилактического средства для предупреждения вышеописанных проблем. Как правило, пациентами и группой риска в этом случае становятся беременные женщины, спортсмены, курильщики, люди с тяжелой физической работой.
Противопоказания
В качестве противопоказания в официальных инструкциях препаратов указана только повышенная чувствительность к основному или вспомогательному компоненту. Это еще раз доказывает высокую безопасность диосмина и гесперидина, а также лекарств на их основе.
Препарат не рекомендуется использовать во время лактации, так как данных о способности проникать в грудное молоко еще недостаточно. Однако у беременных женщин Венарус, Флебодиа и Детралекс не вызвали никакого негативного действия на плод.
Схема приема
Критерием выбора для пациента между препаратами-аналогами часто становится удобство приема. Детралекс и Венарус используются по одинаковой схеме. Они назначаются по 2 таблетки в сутки, которые делят на два приема и пьют через равные промежутки времени.
Таким образом, удается достичь стабильной концентрации действующих веществ в крови и постоянного поддержания терапевтического эффекта. Таблетки принимают во время еды, не разжевывая и запивая обычной водой.
Согласно клиническим исследованиям по препарату Флебодиа 600, в терапии венозной недостаточности оказалось достаточно использовать 1 таблетку в сутки. При необходимости врач может повысить суточную дозу, однако 1 таблетка – оптимальное количество. Через месяц лечения состояние пациента значительно улучшается. При дальнейшем продолжении терапии – структура венозных сосудов и их функции восстанавливаются.
Передозировка
Препараты из группы венотоников предназначены для длительного приема, а большинство из них разрешено применять во время беременности. Все это свидетельствует о высоком профиле безопасности лекарств и низкой вероятности передозировки. В официальных инструкциях к Венарусу, Флебодиа и Детралексу написано, что случаи передозировки этими препаратами неизвестны.
Сравнение венотоников
Отзывы пациентов о том, что лучше при варикозе – Детралекс или Венарус отличаются. Несмотря на одинаковый состав, люди выбирают одно из средств по другим параметрам или личному предпочтению. Некоторые отличия этих лекарств приведены ниже.
| Детралекс | Венарус | Флебодиа | |
| Состав | Два действующих вещества | Два действующих вещества | Один главный компонент |
| Кратность приема в сутки | Дважды | Дважды | 1 раз |
| Производитель | Франция | Россия | Франция |
| Цена за 30 таблеток | 800 р. | 500 р. | 900 р. |
При этом фармакологические эффекты этих препаратов приблизительно одинаковы. Среди них можно выделить:
- Флеботонизирующее действие – повышает тонус вен, уменьшает их растяжимость, усиливает сопротивляемость неблагоприятным факторам.
- Лимфодренажное – увеличивает частоту сокращения лимфатических капилляров, их тонус и функциональную плотность.
- Улучшение микроциркуляции, рассасывание застоев, уменьшение проницаемости капилляров.
- Уменьшение продукции и трансфера медиаторов воспаления в пораженную область, снижение адгезии лейкоцитов, блокирование выработки свободных радикалов.
- Улучшение поступления кислорода к тканям и ускорение процесса регенерации.
Какой препарат выбрать?
Согласно клиническим испытаниям, Флебодиа и Детралекс показали примерно одинаковые результаты и считаются равноценными аналогами.
На вопрос «что лучше при варикозе – Детралекс или Флебодиа?» отзывы докторов распределяются поровну. При этом предпочтение отдается препаратам французского качества, а не российскому Венарусу.
Со стороны пациентов, наоборот, Венарус выбирается достаточно часто. Причиной, как правило, служит то, что Венарус имеет аналогичный Детралексу состав, но более доступную цену. Окончательное решение каждый пациент должен принять самостоятельно, ориентируясь на те критерии, которые для него наиболее важны – качество, цена, схема приема, отзывы других людей.
При регулярном и длительном приеме все венотоники хорошо помогают устранить неприятные симптомы. Эти препараты можно пить и профилактическими курсами два раза в год. Однако фармакологическую эффективность лекарств нужно поддерживать правильной диетой, активным образом жизни и другими методами.
Очень хорошим дополнительным средством для профилактики и даже борьбы с варикозом является компрессионное белье. Более подробно о чулках от варикоза для беременных, а также женском компрессионном белье для спорта при варикозе мы рассказывали в этих статьях.
В некоторых случаях проблема варикоза усложняется локализацией заболевания или невозможностью пациента сменить работу. Сюда относятся грузчики, дальнобойщики, варикоз при беременности, который проявляется в паху, а не на ногах.
Замечайте любые изменения в своем организме. Помните, что первые симптомы варикоза – мелкие сосудистые звездочки и чувство усталости в ногах. Чем раньше начнется лечение, тем эффективнее будет результат.
Детралекс, венарус и флебодиа 600 – самые распространенные препараты при медикаментозном лечении ХВН (хронической венозной недостаточности) и геморроя. Сложно определиться, какое из этих средств лучше. Они в целом аналогичным образом борются с заболеванием. Детралекс и венарус – обладают почти идентичным составом. Венарус выполняет роль российского дженерика (воспроизведенного лекарственного средства, содержащего то же действующее вещество, которое изобрела и запатентовала другая компания) Детралекса. А вот флебодиа составом отличается. Однако при сравнении станет видно, что это лекарство вполне может взаимозаменять указанные ранее препараты.
Основное действующее вещество
Во всех трех препаратах представлено присутствует диосмин, во флебодиа в большей концентрации. В состав детралекса входит микронизированный диосмин – 450 мг и геспередин – 50 мг. Венарус также содержит 450 мг диосмина и 50 мг геспередина. Это значит, что два медикамента идентичны по структуре. Отличаются только страной производителем.
В составе флебодиа содержится единственное активное вещество – диосмин. Его концентрация на 1 таблетку – 600 мг. Лекарство появилось сравнительно недавно. Среди других препаратов выделяется свойством избирательно распределяться по организму. То есть, действовать только в тех участках, где это действительно необходимо.
Показания
Лекарства применяются для лечения болезней, характеризующихся нарушением оттока крови в ногах. Показанием к назначению становится:
- варикозное расширение вен;
- симптомы венозно-лимфатической недостаточности ног.
Также лекарства могут выписываться в целях профилактики перечисленных выше заболеваний. Зачастую доктора прописывают такие средства беременным, курящим, спортсменам, людям с сидячей или стоящей работой, тем, кто часто посещает бани и носит высокие каблуки.
Противопоказания
Детралекс, венарус и флебодиа разрешены к приему во время беременности, единственное, что останавливает использование любого из лекарств – это период лактации у женщин. Пока нет подтвержденной информации о способности медикаментов проникать в грудное молоко. Главными предостережениями к применению также является:
- индивидуальная непереносимость составляющих медикаментов;
- гиперчувствительность;
- детский возраст до 18 лет.
Побочные действия
Прием венаруса и детралекс может сопровождаться следующими побочными эффектами:
- дисперсией, проявляющейся болевым синдромом в области живота;
- аллергической реакцией на диосмин и геспередин;
- невропатическими нарушениями: астенией, головокружением, головной болью.
Использование флебодиа может вызывать:
- сбои в работе ЖКТ;
- реакции на коже в виде высыпаний, зуда, крапивницы.
Любые проявления побочных действий кроме аллергии не могут стать причиной отказа от препарата. Обычно симптомы проходят сами по себе или купируются изменением дозировки медикаментов.
Сходства между препаратами
- Устранение застоев в сосудах;
- Увеличение тонуса вен;
- Уменьшение хрупкости и проницаемости сосудов;
- Улучшение микроциркуляции;
- Снижение растяжения сосудистой стенки.
Главные отличия
- Наличие геспередина в венарусе и детралексе, этот компонент дополнительно придает устойчивости сосудам.
- Флебодия не содержит геспередин, но содержит на 150 мг больше диосмина.
- Отличаются ценой — самый дорогой из трех лекарств — Флебодиа. Самый дешевый — Венарус.
- Венарус и детралекс выпускаются в форме таблеток 500 мг и 1000 мг, тогда как их более дорогой аналог в производится только в форме таблеток 600 мг.
- Разные страны производства — Флебодиа, Детралекс выпускаются во франции, самый дешевый из трех в россии.
- Таблетки 500 мг 30 шт. – 800 р;
- Таблетки 500 мг 60 шт. – 1380 р;
- Таблетки 1000 мг 18 шт. – 920 р;
- Таблетки 15 шт. 600 мг – 690 р;
- Таблетки 18 шт. 600 мг – 732 р;
- Таблетки 500 мг по 30 штук, цена от 490р до 670 р;
- Таблетки 500 мг по 60 штук, цена от 1030р до 1250 р;
- Таблетки 1000 мг по 30 штук, цена от 930р до 1200 р;
- Таблетки 1000 мг по 60 штук, цена от 1950р до 2200 р.
Что лучше: Детралекс, его аналог Венарус или Флебодиа?
Сравнение трех медикаментов показывает, что эффект детралекса наступает быстрее из-за лучшей усваиваемости за счет более современного метода производства. Улучшение состояния проявляется в конце первой недели. Для венаруса время проявления эффекта увеличивается вдвое, однако его низкая стоимость и то, что прием детралекса гораздо чаще вызывает кишечные расстройства, играет в пользу отечественного препарата.
Период полураспада действующих веществ у обоих лекарств составляет 11 часов, поэтому дозировка средств предусматривает двухразовый прием в сутки.
Флебодиа не сможет оказать такого же эффекта, что и детралекс, и венарус, поскольку в его основе только одно вещество. Также Флебодия имеет только одну дозировку — 600мг, а ее аналоги выпускаются в виде 500 и 1000 мг, что делает их более вариативными при различных заболеваниях, и в случае 1000 мг, более действенными в тяжелых стадиях болезни. В любом случае лучше обратиться к врачу, он даст подробный ответ, что выбрать конкретно вам данных лекарств.
Отзывы врачей на препараты: Детралекс, Венарус и Флебодиа
Хирург Викторов В.В.: За время шестнадцатилетней практики детралекс отлично зарекомендовал себя в лечении геморроя и варикоза. Эффект лечения варикоза достигается позже чем с геморроем. Однако он все же положительное влияние на состояние пациентов уменьшая симптомы отечности и боли.
Сосудистый хирург Демидов Д.И.: Большинству пациентов выписываю венарус. Он оптимально сочетает стоимость и эффективность. Хорошо устраняет симптомы венозного застоя, оказывает тонизирующий эффект на стенки сосудов.
Сосудистый хирург Яцков С.К.: Детралекс хорошо справляется с устранением симптомов хронической венозной недостаточности (облегчает боль и снижает отечность). Однако полного выздоровления невозможно достичь медикаментозным путем. В любом случае требуется оперативное вмешательство.
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