Тромбоз – серьезное заболевание, часто приводящее к летальному исходу. Рассмотрим, от чего образуются тромбы в сосудах и как этого избежать.
Виды тромбозов
Тромбоз классифицируют в зависимости от структуры. Выделяют:
- Гиалиновые – формируются в некрупных сосудах;
- Красные характеризуются образованием в венах;
- Белые диагностируются в артериях;
- Смешанные бывают в аорте, венах.
Сами тромбы делятся на:
- Закупоривающие, образующиеся благодаря увеличенному пристеночному тромбу. Они вызывают серьезное нарушение тока крови. Часто наполовину закрывают сосуд;
- Пристеночные. Сгустки крови «размазываются» по краям сосудов. Диагностируется в крупных артериях, венах, сердце;
- Прогрессирующие характеризуется быстрым передвижением с током крови;
- Дилатационные являются наиболее опасными. Определяются в аневризме, отличаются крупными размерами. Отличаются быстрым отрывом и закупоркой сосуда.
Сгусток крови может образоваться в разных видах сосудов. По этому принципу происходит разделение патологии на:
- Артериальные тромбозы – образуются из-за воспалительного процесса, травм. Тромб в артерии сопровождается интенсивной болью, отечностью, покраснением кожного покрова, местным повышением температуры. Если закупорена одна вена, это проявляется отеком, незначительной болью. Общее состояние не изменяется. Сгусток крови, образованный в поверхностных венах, определяется пальпацией. Это свидетельствует о развитии тромбофлебита;
- Венозные – формируются у лиц с нарушением гормонального фона, метаболизма, избытком массы тела. Венозный тромбоз вызывает сбои кровообращения нижних конечностей. Далее нарушается кровоток в легких. Возникает угроза тромбоэмболии легочной артерии.
Причины патологии
Базовые причины образования тромбов в сосудах ног объединены в триаду Вирхова:
- Повышение свертываемости крови. Такой тромбоз не связывают с генетической предрасположенностью. Заболевание возникает на фоне хронических патологий, сопровождающихся повышенной температурой тела, а также в результате злоупотребления алкоголем, диетами, приводящими к обезвоживанию организма. Способствует возникновению тромбоза неконтролируемый прием лекарственных препаратов с мочегонным действием, оральных контрацептивов, гормональных средств, Виагры. Замечено повышение свертываемости крови при частых стрессах, при активном выбросе адреналина, что провоцирует выброс в кровь агрессивных веществ, вызывающих тромбоз;
- Замедленный кровоток. Эта проблема людей, ведущих малоподвижный образ жизни, которые страдают от излишней массы тела, имеют в анамнезе сердечно-сосудистую недостаточность, варикоз вен. Тромбы также появляются из-за нарушенной работы клапанов на фоне беременности, варикоза;
- Травмирование сосудов внутренних тканей – вот еще из-за чего образуются тромбы. Это наблюдается после хирургических операций, внутривенных уколов или травм.
Фиксируется развитие тромбоза на фоне онкологических процессов, воспалительных заболеваний, отравлений токсическими веществами, курения, неправильного питания, когда происходит формирование атеросклеротических бляшек, что объясняется повышенным холестерином.
Механизм тромбообразования
У многих пациентов возникает вопрос, как образуется тромб. Его формирование проходит ряд этапов:
- Стадия агглютинации тромбоцитов. Происходит повреждение стенок сосудов. Тромбоциты склеиваются между собой. Присоединяются к области повреждения. В это время происходит высвобождение активных веществ;
- На следующей стадии образуется фибрин. Тромбоциты становятся базой для дальнейшего формирования сгустка крови в венах. Содержимое белка уплотняется;
- Происходит захват тромбом эритроцитов, лейкоцитов;
- Стадия преципитации. В это время белок крови оседает на сформированном сгустке и уплотняется.
Тромбы в крови прикрепляются к поврежденному очагу. Но фрагмент тромба может в любой момент оторваться. Он попадает в кровоток, вызывая нарушение кровообращения. Тромбоэмболия опасна инфарктом, развивающимся на фоне перекрытого сосуда. Оторваться тромб может в результате воздействия разных факторов:
- Быстрой скорости движения крови по венам;
- Большого размера образовавшегося тромба;
- При прогрессирующих сосудистых заболеваниях;
- Воспалительного процесса вен;
- Непосильной физической активности.
Группа риска
Тромбообразованию подвержен любой человек. Но имеется группа риска к данному заболеванию, в которую входят:
- Онкологические больные;
- Люди, употребляющие мало жидкости;
- Лица, которые совершают частые и длительные перелеты;
- Пациенты, часто переносящие оперативные вмешательства;
- Женщины, предохраняющиеся гормональными контрацептивами;
- Спортсмены, принимающие анаболики;
- Пациенты, перенесшие травмы позвоночника;
- Инвалиды, прикованные к постели;
- Пациенты с ожирением.
Прогноз
Прогноз тромбоза нижних конечностей бывает благоприятным и неблагоприятным. Благоприятным он будет, когда тромб рассасывается и восстанавливается кровоток в вене. Известны случаи канализации тромба. При условии рыхлой структуры у сгустка крови и высокого напора в сосуде, кровь проделывает в вене канал. Происходит полное или частичное восстановление кровотока.
При неблагоприятном прогнозе происходит:
- Прорастанию тромба тканью. Он крепко присоединяется к стенкам вен, нарушая кровообращение;
- Превращение тромба в эмбол в результате отрыва;
- Инфицирование сгустка крови гноем, что вызывает распространение микроорганизмов по организму;
- Образование тромбоза во множественных микрососудах, вызывая кровоизлияние вен.
Профилактика тромбоза
Избежать тромбообразования можно, соблюдая следующие несложные рекомендации:
- Гиподинамия приводит к застоям крови в венах, ухудшает процессы обмена веществ. Нельзя допускать длительного нахождения в одном положении. При сидячей работе следует делать регулярные паузы, небольшую зарядку;
- Важно пить больше воды, не меньше 1,5 л. в день. Вода является отличным средством разжижения крови;
- Следует беречься от травм, повышать иммунитет;
- Избегать злоупотребления алкоголем, отказаться от курения;
- Контролировать вес;
- По возможность избегать стрессов;
- Придерживаться правильного питания.
Зная, почему образуются тромбы, можно избежать развития тромбоза и его осложнений, которые без адекватной своевременной терапии могут привести к смертельному исходу.
Основные причины тромбообразования
Тромбы появляются в кровеносной системе человека при замедленном кровотоке, высокой вязкости крови и нарушении целостности внутренней поверхности сосудов. Образовавшийся в виде сгустка, пристеночный тромб может располагаться:
- при аневризме – в сердце;
- при атеросклерозе – в крупных артериях;
- при воспалении – в венах.
Чаще всего образуется тромб обтурирующий, который особенно опасен для здоровья и жизни человека.
Замедленный кровоток
В группу риска попадают люди с малоподвижным образом жизни, страдающие варикозом и повышенным артериальным давлением. У них образование кровяных сгустков происходит из-за нарушения нормального кровотока, застоя, появления турбулентности крови в вене.
Высокая вязкость крови
Причина тромбообразования, может быть в очень вязкой внутрисосудистой жидкости. Тромбы могут появляться у всех, кто страдает:
- аутоиммунным и онкологическим заболеванием;
- генетической патологией системы свертывания крови;
- обезвоживанием.
Разрушение внутренней оболочки сосуда
Причины образования тромбов в сосудах могут быть в их атеросклеротических изменениях. На холестериновых бляшках, представляющих собой жировые наросты, постепенно откладывается кальций. Сосуды теряют свою эластичность, становятся хрупкими и изъязвленными. Выполняя свое непосредственное предназначения, кровь тромбирует разрушенную внутреннюю оболочку, частично закрывая проход для основного кровотока. Часто кровяные сгустки появляются после хирургического лечения, когда не была проведена профилактическая антикоагулянтная терапия.
К нежелательному последствию ведет неконтролируемый прием оральных контрацептивов. Это еще одна причина, отчего образуются тромбы в сосудах.
В зависимости от места образования развивается артериальный и венозный тромбоз. Каждый из них имеет свои симптомы и последствия, которые могут возникать и проявляться по-разному.
Причины артериального тромбоза
Одной из причин снижения кровотока и сужения артерий считается облитерирующий атеросклероз. Откладываясь на стенке артерий, холестерин и липидные включения постепенно преобразуются в атеросклеротическую бляшку. Организм оценивает ее как дефект, осаждает тромбоциты и сгустки фибрина. Так происходит образование рыхлого, а затем очень плотного сгустка крови.
Причина тромбоза вен
В отличие от артериального, в венозном сосуде холестерин не откладывается. В этом случае главной причиной, как и при артериальном тромбозе, является разрушение внутренней оболочки вен. Это бывает в двух случаях:
- При тромбофлебите сгусток появляется на воспаленной стенке вены. При этом воспаление может вызвать вирусная или бактериальная инфекция, врожденный или приобретенный порок клапанов, варикоз и др.
- При флеботромбозе тромб появляется без воспаления.
Венозный тромбоз может начаться с воспаления окружающих его тканей и привести к сепсису. Поэтому очень опасен.
В сердце
Образование тромбов в сердце может быть из-за нарушения нормального кровотока, то есть в его замедлении или образовании завихрения. Они могут образоваться после инфаркта миокарда, с нарушением питания его тканей, или после оперативного вмешательства.
Причиной может быть врожденный или приобретенный порок сердца, токсическое или инфекционное поражение миокарда, атеросклеротические процессы.
Образованные в полости сердца тромбы могут оторваться и перемещаться по большому кругу кровообращения. Они сами или их фрагменты впоследствии становятся причиной тромба в головном мозге, в селезенке, почках или кишечнике.
В сосудах мозга
Серьезную опасность для здоровья человека представляют тромбы в артериальных сосудах головного мозга. Причинами их появления являются атеросклеротические бляшки, спазм при гипертоническом кризе, аневризма, сосудистая мальформация.
Возможно образование и венозного тромба. Причины нарушения кровотока в вене – септическое состояние или гнойничковый очаг в черепной коробке или за ее пределами.
В легких
Чаще всего причиной тромба легочных сосудов является эмболия фрагментов кровяных сгустков, которые потоком крови были перенесены из глубоких вен нижних конечностей.
Если в сосудах легких появился тромб, возникает необходимость его срочного удаления.
При неоказании своевременной врачебной помощи возникает серьезная опасность для жизни человека.
Предрасполагающие факторы
Риск появления тромба всегда есть при имеющихся в организме предрасполагающих факторах.
Это заболевание сахарным диабетом, мерцательная аритмия, облитерирующий эндокардит с сужением артериального сосуда вследствие хронического воспаления, повышенная свертываемость крови и ряд других хронических заболеваний.
Должны насторожить некоторые признаки образования тромба в ноге. Появление резкой боли, усиливающейся при активном движении или длительном стоянии. Отек, появление сосудистой сетки, посинение и холод в конечности – признак тромба в подвздошной или бедренной вене.
Как предотвратить тромбы
Позаботиться о своем здоровье и постараться не допустить непроходимость сосудов может каждый, для этого достаточно:
- употреблять только здоровую пищу;
- вести подвижный образ жизни;
- контролировать вязкость крови.
Важно держать в норме холестерин крови, приучить себя к здоровому питанию. Больше пользы будет, если увеличить употребление рыбы, овощей, зелени и фруктов. В то же время надо ограничить употребление животного жира. Поддержать на нужном уровне свертываемость крови помогут зеленый чай, свекла и вишня. Конечно, если врачом назначен Аспирин или Варфарин, их тоже надо принимать.
Чтобы поддерживать себя в хорошей физической форме нужно 30 минут в день посвящать физическим упражнениям, совершать пешеходные прогулки на воздухе. Это позволит всем кто ведет малоподвижный образ жизни избежать образования тромбов. Касается это всех офисных работников и людей, совершающих длительные авиаперелеты. Больным рекомендуется потихоньку ходить, а послеоперационным пациентам дополнительно выполнять эластичное бинтование ног.
Ознакомившись с причинами образования тромбов, следует позаботиться о предупреждении их образования и сохранении своего здоровья. Сделать это вполне доступно каждому.
О процессе образования кровяных сгустков в организме слышал, пожалуй, каждый из нас. Вместе с тем, мало кому известно, от чего образуются тромбы, и почему это явление несет в себе опасность для жизни человека. А ведь именно эти образования — основная причина развития острого инфаркта миокарда и инсульта головного мозга, а также некротической ишемии кишечника, тромбоэмболии легочных артерий, тромбофлебита нижних конечностей, варикозной болезни и многое другое.
Тромбы являются очень частой причиной внезапной смерти людей разного возраста. Именно поэтому важно знать, что они собой представляют и откуда берутся, чтобы вовремя предупредить их образование. Обычный тромб – это не что иное, как сгусток крови, состоящий из форменных элементов крови, фибрина, холестерина. Наиболее часто образования формируются в венах нижних конечностей, реже – в полостях сердца и мелких сосудах брюшной полости. От чего образуются тромбы, и какими они бывают? Что поможет определить наличие сгустков в сосудах, и как избавиться от тромбов? Ответы на эти и другие вопросы поможет найти статья, изложенная ниже.
Как образуются кровяные сгустки?
Учеными доказано, что тромбы время от времени возникают у каждого второго жителя нашей планеты. Но благодаря слаженной работе свертывающей и противосвертывающей системы, эти образования самопроизвольно рассасываются, не причиняя вреда здоровью человека.
Только при запуске патологических механизмов в организме или под влиянием определенных факторов, сгустки крови прилипают к стенке сосуда, увеличиваются в размерах и становятся преградой для нормального кровотока.
От чего образуются тромбы в сосудах на самом деле?
Состояние, когда изменяются реологические свойства крови, возникает по разным причинам, среди которых следует выделить несколько основных групп:
- инфекционные воспалительные процессы в организме, которые влияют на синтез фибрина и активируют огромное количество ферментов, способных вызывать лизис телец крови и ее сгущение;
- травмы, включая переломы, надрывы связок, обширные гематомы и тому подобное;
- оперативные вмешательства, а также естественные роды;
- экстраваскулярные патологии, среди которых сердечные недуги, ожирение, гипергликемия, онкологические патологии;
- неоднократные внутривенные вливания лекарственных препаратов;
- длительный прием медикаментов, сгущающих кровь;
- аллергические реакции, аутоиммунные процессы.
Причины образования тромбов
В ходе многочисленных исследований ученым удалось подтвердить влияние на реологические свойства крови трех основных факторов, которые способны запускать механизмы патологического образования тромбов. В медицине это явление известно под названием триада Вирхова. Итак, существуют такие причины, почему образуются тромбы:
- Повреждение стенки сосуда. Механизмы подобного процесса могут быть самыми разнообразными, но наиболее часто к нему приводит разрыв сосуда, разъедание его стенки атеросклеротическими отложениями, истончение интимы в результате воспалительных заболеваний оболочек артерий и вен, потеря эластичности, повышение давления крови внутри сосуда и тому подобное.
- Нарушение реологических свойств крови с тенденцией к повышенному ее свертыванию. Повышенное свертывание вызывается в большинстве клинических случаев увеличением количества тромбоцитов и эритроцитов в кровяном русле, которые влияют на скорость формирования тромба и способность образовывать пристеночные сгустки. Кроме этого, увеличенное количество форменных элементов крови позволяет уже сформированному тромбу расти и увеличиваться в диаметре. Реже нарушение свертывания крови вызывается изменениями в гормональном фоне человека. Данная проблема особенно актуальна для женщин, которые предупреждают нежелательную беременность с помощью приема оральных контрацептивов. Такие таблетки существенно влияют на баланс женских половых гормонов, а также полностью меняют обмен веществ в организме.
- Застойные явления. Застой крови в нижних конечностях у людей, которые часами вынуждены находиться в сидячем или лежачем положении, приводит, как правило, к образованию тромботических сгустков, перекрывающих просвет сосудов.
Кто принадлежит к группе риска?
Причины возникновения тромбов определяют несколько категорий потенциальных пациентов, у которых имеются предпосылки к патологическому свертыванию крови.
Врачи предупреждают, что главным фактором риска по развитию патологий свертывающей системы крови является неправильный образ жизни, погрешности в пищевом рационе, вредные привычки и тому подобное.
Кроме этого, задуматься о здоровье своих сосудов и принять меры, направленные на предупреждение тромбоза, следует следующим категориям населения:
- люди старшего возраста, у которых в анамнезе присутствуют ишемия сердечной мышцы, транзиторные ишемические атаки головного мозга, хроническая венозная недостаточность, тромбоэмболия, инфаркт миокарда;
- онкологические больные;
- беременные женщины, у которых нарушен синтез естественных антикоагулянтов и замедлен ток крови по сосудам, нередко страдают тромбофлебитом вен нижних конечностей;
- пациенты хирургического стационара, перенесшие оперативные вмешательства на венах и органах малого таза, что может привести к возникновению застойных явлений в брюшной полости и нарушению кровотока по направлению от нижних конечностей к сердцу;
- люди, принимающие медикаменты, которые обладают свойством повышать вязкость крови и формировать тромбы;
- пациенты после травм, которые сопровождались кровотечением и кровопотерей, или пережившие многократное травмирование мягких тканей с образованием гематом люди;
- женщины и мужчины, ведущие малоподвижный образ жизни, у которых замедляются метаболизм, и развивается та или иная степень ожирения;
- представители семей, где уже были подобного рода заболевания;
- любители жирной пищи, алкоголя, мучных продуктов с повышенным содержанием веществ, способствующих повышению в крови количества вредного холестерина.
Учитывая все причины образования тромбов в сосудах, несложно сделать логический вывод. Предупредить недуги, связанные с нарушением свертывающей функции, можно с помощью простых мероприятий, направленных на нормализацию режима и качества питания, повышение двигательной активности и употребление в пищу естественных, а также искусственного происхождения антикоагулянтов в профилактических дозах.
Виды кровяных сгустков в зависимости от механизмов их развития
В процессе формирования все тромбы проходят определенные этапы развития, в зависимости от течения и направленности которых среди общего количества сгустков крови выделяют:
- белые тромбы или сгустки из тромбоцитов (образуются медленно, преимущественно в капиллярах);
- красные тромбы, эритроцитарные (формируются очень быстро при замедленном токе крови в венах);
- бело-красные смешанные тромбы (локализуются преимущественно в полостях сердца и в зоне аневризмы аорты);
- гиалиновые сгустки (появляются тромбы в мелких сосудах органов грудной и брюшной полости, в которых количество плазмы превышает количество кровяных телец).
В зависимости от размеров и расположения тромба по отношению к просвету сосуда различают:
- пристеночный тромб или прикрепленный к стенке сгусток, перекрывающий не более половины просвета кровеносного сосуда;
- закупоривающий просвет сосуда тромб, занимающий более половины внутреннего диаметра вены или мелкой артерии;
- прогрессирующий, стремительно растущий по ходу тока крови тромб может достигать бассейна собирательных вен;
- сгусток шаровидной формы – пристеночный тромб левого предсердия, который очень часто отрывается, перекрывая просвет сосудов по ходу тока крови;
- дилятационный тромб, как правило, возникает в аневризме аорты и, когда отрывается, полностью прекращает кровоток.
Особенности диагностики
Не зависимо от причины возникновения тромбов, всем пациентам, находящимся в группе риска, показана диагностика тромбоза, которая позволит определить заболевание на его начальных стадиях развития и принять меры по его устранению.
Современная диагностика тромбоза включает в себя несколько этапов:
- лабораторная диагностика с проведением коагулограммы, клинического анализа крови, определения присутствия Д-димера (способна дать объективную оценку количественному составу крови, определить присутствие в ней фрагментов распада тромба и тому подобное);
- инструментальное определение наличия изменений со стороны сосудистой стенки и собственно тромбов, которое реализуется с помощью ультразвука, рентгенодиагностики, МРТ, компьютерной томографии.
Методы диагностики тромбоза позволяют не только констатировать факт присутствия тромбов на стенках сосудов или в кровяном русле, но и предположить возможные причины, почему образуются тромбы в организме конкретного человека.
Это позволяет рассматривать патологический процесс с точки зрения его этиологии и проводить лечение, направленное на устранение провоцирующих формирование кровяных сгустков факторов.
Основные методы лечения патологии
В зависимости от чего появляются тромбы у пациента, врач принимает решение о выборе той или иной тактики его лечения. В настоящее время тромбоз поверхностных вен устраняется с помощью терапевтических методик в амбулаторных условиях. Тогда как больные с поражением глубоких вен нуждаются в детальной диагностике, помещении в стационар и интенсивном лечении, которое нередко бывает хирургическим.
Лекарственная терапия реализуется путем употребления пациентом препаратов, которые разжижают кровь, укрепляют стенки сосудов, устраняют проявления местного воспаления. Оперативное лечение назначается только людям по строгим показаниям, которые страдают от декомпенсированных патологических процессов, связанных с повышением свертываемости крови. Пациентам может быть предложено шунтирование (замена участка) сосудов, тромбэктомия (удаление тромба), имплантация кава-фильтра (специальный фильтр, который предупреждает продвижение тромбов к сердцу и легким), венозная ангиопластика (оперативное устранение дефекта станки сосуда) и тому подобное.
В чем главная опасность?
Образование тромбов в сосудах — весьма опасный для нормальной жизнедеятельности человеческого организма процесс, который может повлечь за собой развитие неотложных состояний, нередко заканчивающихся летальным исходом. Помимо того, что сгустки крови замедляют основной кровоток, они еще и являются причиной возникновения:
- скрытого тромбоза, когда сгустки мигрируют по организму и чаще всего оседают в сердце, провоцируя его дисфункцию или внезапную остановку;
- тромбоэмболии легочной артерии, которая возникает в результате перекрытия тромбом одной или нескольких легочных сосудов, что в клинической практике проявляется инфарктом легочной ткани или асистолией.
Тромбоз вен нижних конечностей опасен возникновением посттромбофлеботического синдрома. Как известно, со временем сгустки имеют способность рассасываться, во время чего выделяется большое количество продуктов их распада, которые губительно влияют на венозные клапаны, разрушая их структуру. Дисфункция клапанного аппарата вен нижних конечностей приводит к недостаточности кровотока, особенно в нижней части ног, с развитием отечности, варикозного расширения, лимфостаза и тому подобное.
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