ТРОКСЕВАЗИН — форма выпуска, состав и упаковка
◊ Капсулы твердые желатиновые, размер №1, цилиндрические, желтого цвета; содержимое капсул — порошок от желтого до желто-зеленого цвета, допускается наличие конгломератов, которые при надавливании распадаются.
1 капс. | |
троксерутин | 300 мг |
[PRING] лактозы моногидрат — 47 мг, магния стеарат — 3 мг.
Состав оболочки: краситель хинолиновый желтый (E104) — 0.9%, краситель солнечный закат желтый (E110) — 0.039%, титана диоксид (E171) — 3%, желатин — до 100%.
10 шт. — блистеры (5) — пачки картонные.
10 шт. — блистеры (10) — пачки картонные.
◊ Гель для наружного применения 2% от желтого до светло-коричневого цвета.
1 г | |
троксерутин | 20 мг |
[PRING] карбомер — 6 мг, троламин (триэтаноламин) — 7 мг, динатрия эдетата дигидрат — 0.5 мг, бензалкония хлорид — 1 мг, вода очищенная — 965.5 мг.
40 г — тубы алюминиевые (1) — пачки картонные.
40 г — тубы ламинатные (пластиковые) (1) — пачки картонные.
◊ Капсулы твердые желатиновые, размер №1, цилиндрические, желтого цвета; содержимое капсул — порошок от желтого до желто-зеленого цвета, допускается наличие конгломератов, которые при надавливании распадаются.
1 капс. | |
троксерутин | 300 мг |
[PRING] лактозы моногидрат — 47 мг, магния стеарат — 3 мг.
Состав оболочки: краситель хинолиновый желтый (E104) — 0.9%, краситель солнечный закат желтый (E110) — 0.039%, титана диоксид (E171) — 3%, желатин — до 100%.
10 шт. — блистеры (5) — пачки картонные.
10 шт. — блистеры (10) — пачки картонные.
Фармакологическое действие
Ангиопротекторный препарат, действует преимущественно на капилляры и вены.
Уменьшает поры между эндотелиальными клетками за счет модификации волокнистого матрикса, расположенного между клетками эндотелия. Ингибирует агрегацию и увеличивает степень деформируемости эритроцитов; оказывает противовоспалительное действие.
При хронической венозной недостаточности Троксевазин уменьшает выраженность отека, боли, судорог, трофических расстройств, варикозных язв. Облегчает симптомы, связанные с геморроем — боль, зуд и кровотечение.
Благодаря благоприятному воздействию на проницаемость и резистентность стенок капилляров, Троксевазин способствует замедлению развития диабетической ретинопатии. Кроме того, его влияние на реологические свойства крови способствует предотвращению микротромбоза сосудов сетчатки.
Фармакокинетика
После приема внутрь абсорбция составляет около 10-15%. C max в плазме крови достигается в среднем через 2 ч после приема, терапевтический уровень в плазме сохраняется в течение 8 ч.
Метаболизм и выведение
Метаболизируется в печени. Частично выводится в неизмененном виде с мочой (20-22%) и с желчью (60-70%).
Дозировки препарата ТРОКСЕВАЗИН
Препарат принимают внутрь, во время еды. Капсулы следует проглатывать целиком, запивая достаточным количеством воды.
В начале лечения назначают по 300 мг (1 капс.) 3 раза/сут. Эффект обычно развивается в течение 2 недель, после этого лечение продолжают в той же дозе или снижают до минимальной поддерживающей — 600 мг, либо приостанавливают (при этом достигнутый эффект сохраняется в течение не менее 4 недель). Курс лечения составляет в среднем 3-4 недели, необходимость более длительного лечения определяется индивидуально.
При диабетической ретинопатии назначают в дозе 0.9-1.8 г/сут.
Лекарственное взаимодействие
Действие препарата усиливается при одновременном приеме аскорбиновой кислоты.
Применение ТРОКСЕВАЗИН при беременности
Данные о применении препарата Троксевазин в I триместре беременности не предоставлены.
Во II и III триместрах и в период лактации (грудного вскармливания) применение препарата возможно в случае, когда ожидаемая польза терапии для матери превышает потенциальный риск для плода или грудного ребенка.
Применение в детском возрасте
Опыт применения препарата у детей младше 15 лет отсутствует.
ТРОКСЕВАЗИН — побочные действия
Со стороны пищеварительной системы: тошнота, диарея, изжога, эрозивно-язвенное поражение ЖКТ.
Прочие: кожная сыпь, головная боль, приливы крови к лицу.
Побочные эффекты быстро исчезают после прекращения лечения.
Условия и сроки хранения препарата ТРОКСЕВАЗИН
Препарат следует хранить в недоступном для детей, сухом, защищенном от света месте при температуре не выше 25°С. Срок годности — 5 лет.
Показания к использованию ТРОКСЕВАЗИН
— хроническая венозная недостаточность;
— трофические нарушения при варикозной болезни;
— в качестве вспомогательного лечения после склеротерапии вен и удаления варикозных узлов;
— геморрой (боль, экссудация, зуд, кровотечение);
— венозная недостаточность и геморрой при беременности, начиная со II триместра;
— в качестве вспомогательного лечения ретинопатии у больных сахарным диабетом, с артериальной гипертензией и атеросклерозом.
Особые указания при приеме ТРОКСЕВАЗИН
Если в период применения препарата выраженность симптомов заболевания не уменьшается, следует проконсультироваться с врачом.
Использование в педиатрии
Опыт применения препарата Троксевазин у детей младше 15 лет отсутствует.
Влияние на способность к вождению автотранспорта и управлению механизмами
Прием препарата не оказывает влияния на двигательные и психические реакции, не препятствует управлению транспортными средствами и работе с механизмами.
Условия отпуска из аптек
Препарат ТРОКСЕВАЗИН разрешен к применению в качестве средства безрецептурного отпуска.
*Описание препарата основано на официально утвержденной инструкции по применению и утверждено компанией-производителем для изданий 2012 года
ТРОКСЕВАЗИН — описание и инструкция предоставлены справочником лекарственных средств «Видаль»
Инструкция по применению:
Цены в интернет-аптеках:
Троксевазин (Troxevasin) – ангиопротекторный препарат с противоотечным и противовоспалительным действием, применяемый при лечении венозной недостаточности, варикоза и др.
Фармакологическое действие Троксевазина
Активным компонентом Троксевазина является троксерутин, который проявляет Р-витаминную активность и представляет собой полусинтетическую производную рутина с преобладающей тригидроксиэтилрутозида. Препарат уменьшает ломкость капилляров и оказывает ангиопротективное, венотонизирующее, антиоксидантное и противовоспалительное действие.
Форма выпуска Троксевазина
Лекарство Троксевазин выпускают в форме геля для наружного применения и в капсулах. Одна твердая, цилиндрическая, желтого цвета желатиновая капсула Троксевазина по инструкции содержит 300 мг троксерутина, 47 мг моногидрата лактозы и 3 мг стеарата магния. В состав оболочки входит 0,9% желтого хинолинового красителя Е104, 3% диоксида титана Е171, 100% желатина и 0,039% желтого красителя солнечный закат Е110.
В состав 2% геля Троксевазин по инструкции входят 20 мг троксерутина, 6 мг карбонара, 0,5 мг динатрия этилендиаминтетрауксусной кислоты, 1 мг хлорида бензалкония, 7 мг триэтаноламина и 965,5 мг очищенной воды.
Аналоги Троксевазина
Аналогами Троксевазина по активному компоненту являются:
- Троксерутин Ветпром;
- Троксерутин-МИК;
- Троксевенол;
- Троксерутин Врамед;
- Троксерутин Зентива.
К аналогам Троксевазина по принадлежности к одной фармакологической группе и оказываемому действию относят:
- Асковертин;
- Аскорутин Д;
- Вазокет;
- Венолек;
- Венорутон;
- Диосмин;
- Рутин;
- Флебодиа 600;
- Югланэкс.
Показания к применению Троксевазина
Согласно инструкции Троксевазин назначают при гематомах, вывихах, ушибах, растяжениях, контузиях, мышечных спазмах, а также в случаях:
- Побочных сосудистых эффектов лучевой терапии;
- Послеварикозного синдрома;
- Варикозного расширения вен;
- Острого поверхностного тромбофлебита и перифлебита;
- Диабетической микроангиопатии;
- Хронической венозной недостаточности;
- Язвенного поражения кожи и дерматита на фоне варикозного расширения вен;
- Геморроя;
- Варикозных язв.
В случае геморроя и венозной недостаточности при беременности Троксевазин назначают со второго триместра. Также медикамент используется в качестве дополнительного лечения при сосудистом нарушении сетчатки глаз у пациентов с артериальной гипертензией, сахарным диабетом и атеросклерозом.
Способ применения Троксевазина
На основании инструкции Троксевазин в капсулах применяется внутрь во время еды. Дозировка средства составляет 2 капсулы один раз в день, при поддерживающей терапии доза составляет 1 капсула в день на протяжении месяца.
Троксевазин в виде геля наносится легкими массирующими движениями на пораженные участки кожи, дважды в день утром и вечером, до полного проникновения в кожу. Медикамент применяется регулярно в течение длительного периода времени, наносится исключительно на неповрежденную поверхность.
Противопоказания
По инструкции Троксевазин противопоказан к применению в случаях хронического гастрита, повышенной чувствительности к медикаменту и его компонентам, язвенной болезни желудка и 12-перстной кишки. С осторожностью медикамент назначают в случаях почечной недостаточности. При беременности Троксевазин противопоказан к назначению в первый триместр.
Побочные действия Троксевазина
Применение Троксевазина по отзывам приводит к осложнениям крайне редко, случаи передозировки медикаментом неизвестны. В редких случаях Троксевазин по отзывам вызывает дерматит, экзему и крапивницу. Если лекарство вызывает другие, не описанные выше побочные действия, необходимо срочно обратиться к врачу.
Условия хранения
В соответствии с инструкцией Троксевазин в капсулах отпускается только по назначению врача, в форме геля без рецепта. Лекарство необходимо хранить в сухом, проветриваемом и защищенном от попадания света помещении, при температуре от 15 до 25°C.
Каждый из нас может столкнуться с заболеваниями вен. Все чаще и чаще к флебологам обращаются пациенты, страдающие расширением венозных сосудов, а также различными формами тромбозов. Существует большое количество препаратов, предназначенных для решения таких проблем. Наиболее эффективным медики считают гель Троксевазин.
Описание и состав
Данный медикамент выпускается в виде геля, предназначен для наружного применения. Такая форма выпуска позволяет применять лекарство в домашних условиях. Мазь помещена в алюминиевый тюбик, содержащий 40 граммов лекарства.
В состав препарата входит активное вещество троксерутин, оказывающее отличный лечебный эффект на человеческий организм. Также в составе имеются вспомогательные ингредиенты: очищенная вода, карбомер, троламин и бензалкония хлорид.
Мазь имеет немного вязкую консистенцию и коричневатый оттенок. Для максимально эффекта врачи советуют использовать препарат «Троксевазин» в таблетированной форме.
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В каких случаях применяется
Чаще всего гель «Троксевазин» специалисты назначают против варикозного расширения вен. Однако данный медикамент имеет очень широкий спектр применения, и может быть назначен для устранения других недугов. Рассмотрим, когда же еще можно применять этот препарат:
- при наличии гематом, ушибов, а также вывихов;
- средство отлично справляется с различными патологиями сосудов, которые возникли после применения лучевой терапии;
- лекарство очень хорошо себя показало при лечении хронической венозной недостаточности и варикозных язв;
- также препарат очень хорошо себя зарекомендовал при лечении геморроя.
Перед применением тщательно изучите состав «Троксевазина» и посоветуйтесь с доктором. Самолечение может привести к крайне плачевным последствиям.
Как молодой организм реагирует на Троксевазин, можно ли детям его использовать. Согласно инструкции по применению, применять данное средство можно только лицам, достигшим четырнадцатилетнего возраста. Бывают случаи, когда врач назначает этот препарат детям. В этом случае нужно внимательно смотреть на реакцию малыша, и при возникновении первых отрицательных явления сразу же прекращать использование. Если вас интересует, можно ли детям Троксевазин, обязательно спросите об этом у доктора. Только он сможет вам дать однозначный ответ, ведь каждый случай уникальный.
Если вы страдаете такой патологией, как повышенная проницаемость сосудов, то в этом случае использовать препарат лучше всего с аскорбиновой кислотой. Так эффект от лечения наступит гораздо быстрее, и его результативность увеличится в несколько раз.
Средство можно использовать водителям автомобилей, а также тем людям, которые работают с серьезными механизмами. Вещества, входящие в состав мази, не влияют на психомоторные реакции.
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Несколько слов о фармакодинамике
Многие пациенты интересуются, Троксевазин — гормональный гель или нет. На этот вопрос вы сможете найти ответ ниже. Активные вещества, входящие в состав данного лекарства, оказывают на человеческий организм неплохое лечебное воздействие. А именно:
- улучшает тонус сосудов, и защищает их от неблагоприятного воздействия окружающей среды;
- активные вещества, входящие в состав, неплохо снимают воспаления, а также оказывают на организм антиоксидантное воздействие;
- прекрасно убирает отечности, что очень важно при запущенных формах варикозного расширения вен;
- предотвращает возникновение тромбов;
- нормализует обменные процессы в организме;
- снижает болевые ощущения.
Действенные вещества начинают свое активное воздействие на тело человека уже через полчаса после нанесения геля на поверхность кожи. Средство очень быстро впитывается, поэтому лечебный эффект будет заметен уже после первого применения.
Наличие противопоказаний
И так, будьте готовы к тому, что далеко не во всех случаях можно использовать препарат «Троксевазин». При этом форма выпуска не имеет значения. Неважно, что вы собираетесь использовать, капсулы, или гель, обязательно проконсультируйтесь с опытным специалистом перед тем, как начать лечение.
Рассмотрим, в каких же случаях использовать гель Троксевазин. Инструкция по применению запрещает использовать препарат:
- при наличии таких заболеваний желудочно-кишечного тракта, как гастрит или язва;
- людям, имеющим повышенную чувствительность к составляющим препарата, перед началом использования геля рекомендуется провести тест на чувствительность;
- пациентам, страдающим почечной или печеночной недостаточностью, а если решили применять, то делать это надо под постоянным контролем лечащего врача.
Многие женщины задают вопрос, можно ли использовать мазь «Троксевазин» во время беременности. По словам специалистов, беременная женщина может использовать лечебное средство только в первом триместре. Затем применение данного лекарства придется прекратить.
Как видите, противопоказания к применению не так многочисленны.
Способы нанесения
После приобретения Троксевазин способ применения препарата должен быть изучен в первую очередь, чтобы лечение было максимально результативным и не причинило существенного вреда здоровью.
Перед тем, как наносить данный препарат, очень важно хорошенько очистить кожу, вытереть ее насухо махровым полотенцем. Наносить гель нужно массажными движениями тонким слоем на пораженные участки кожи. Врачи рекомендуют пользоваться мазью два-три раза в день.
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Если лекарство будет использоваться при геморрое, то наносить его можно только после очищения кишечника и проведения гигиенических процедур. Специалисты рекомендуют наносить средство на марлевые тампоны и прикладывать их на область ануса. По словам пациентов, такая процедура очень быстро приводит к возникновению положительного результата.
Существует ли побочный эффект
При наличии повышенной чувствительности к отдельным компонентам, входящим в состав данного лекарства, могут возникнуть аллергические реакции в виде сыпи, кожного зуда, крапивницы и отечности.
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