Трофические язвы являют собой дефект кожи или слизистой оболочки тканей в виде открытой раны, не заживающей более месяца. Такое заболевание характеризуется главным образом несклонностью к самозаживлению тканей, частым обострениям и прогрессирующему некрозу. Однако основной негативной особенностью трофической язвы является ее склонность к возвращению симптомов в случае, если не локализована и не устранена изначальная причина вызвавшая заболевание.
Данное повреждение является симптомом множества заболеваний, таких как хроническая венозная недостаточность, появляется на последних стадиях варикозного расширения вен, а также при долгом и неконтролируемом развитии различных кожных заболеваний. Развитию трофической язвы сопутствуют, как правило, нарушения в циркуляции крови и лимфы, разрушение нервных клеток, мягких тканей и кожи, а также повреждения спинного мозга и центральной нервной системы. Чаще всего трофические язвы образуются в виде одиночных или множественных повреждений в нижней трети голени и самой стопе. Язва имеет неправильную округлую форму, реже встречается в форме кольца, охватывающего голень. Края поражения плотные, имеют синеватую или коричневую окраску, дно язвы неглубокое и плоское с выделениями мутной жидкости.
Язвы, как симптом, классифицируют в зависимости от причины возникновения. Трофические язвы бывают: венозными, артериальными, гипертоническими, диабетическими, нейротрофическими, инфекционными, озлокачественными, так же могут являться на фоне кожных заболеваний и лимфостаза.
Виды трофических язв
Наиболее распространенной формой трофической язвы является венозная. Проявляется на последней стадии варикозного расширения вен и после перенесенных тромбофлебитов глубоких вен. Затруднение венозного оттока крови нарушает питание тканей и вызывает некроз. Венозные язвы появляются на внутренней поверхности голени, сопровождаются отеком нижней конечности, а также, тяжестью и болью в нижней трети конечности.
Артериальные трофические язвы развиваются на фоне атеросклероза. Артериальные сосуды при данном заболевании меняют форму, как следствие затрудняется поступление кислорода и питательных веществ в мягкие ткани, что вызывает возникновение язвы. Некроз возникает на различных участках стопы, в основном в области пятки и на фаланге большого пальца. Проявляются поражениями небольшого размера с характерно выраженными болевыми спазмами при физических нагрузках и придании возвышенного положения ноге.
Диабетическая язва наблюдается у пациентов, страдающих сахарным диабетом. Такая патология развивается из-за нарушения циркуляции крови в мелких сосудах. Возникает на фалангах пальцев стопы. Для данного вида язвы характерно отсутствие боли в местах поражений.
Нейотрофические язвы развиваются при повреждениях спинного мозга или нервных стволов. Повреждения большеберцового и седалищного нервов при данных заболеваниях может сопровождается некрозом, возникающим по причине иннервации тканей нижних конечностей. Язвы возникают в зонах нарушения иннервации: на пяточном бугре, наружной половине стопы, подошвенной поверхности большого пальца нижней конечности и т.д. Основными характерными особенностями данной патологии являются долгое заживление и отсутствие боли в пораженных участках.
На фоне гипертонической болезни возможны возникновения гипертонической трофической язвы. Причиной патологии является сужение мелких артерий. Локализация некроза – передняя поверхность голени, поражения сопровождаются ярко выраженными болевыми ощущениями. Чаще всего встречается у пациентов старше 40 лет.
Инфекционные язвы возникают во время снижения иммунитета, при попадании болезнетворных микроорганизмов через мельчайшие повреждения кожного покрова. Сопровождается болью в суставах, увеличением лимфоузлов, ознобом и повышенной температурой тела.
На фоне заболеваний кожи с длительным периодом эпителизации, таких, как экзема и дерматит, так же возможно возникновение трофических язв.
Нередко причиной является лимфостаз, возникающий при нарушениях в образовании и оттоке лимфы. При лимфостазе трофические язвы располагаются в нижней трети голени.
Злокачественные язвы являются ухудшенным состоянием трофической язвы, возникшей в следствие неконтролируемого развития болезни. Малигнизация язвы происходит в результате ряда негативных факторов, таких как: частое травмирование пораженной области, рецидивов, использования раздражающих кожу средств. Патологии свойствен гнилостный запах, сильное припухание пораженного участка и значительное увеличение лимфоузлов в паховой области.
Лечение трофических язв довольно длительный процесс. Язва является лишь симптомом основного заболевания. Важно помнить о том, что к лечению следует подойти комплексно. Необходимо сочетание не только патогенетического и этиологического методов лечения, то есть устранения основной причины патологии и применение антибактериальных препаратов, но и применение местных методов лечения.
Местное лечение направлено на скорейшее заживление раны. Метод такого лечения определяется стадией течения раневого процесса трофической язвы, независимо от ее вида и происхождения.
Протекание раневого процесса трофической язвы делят на четыре стадии.
Первая стадия проходит, как возникновение и прогрессирование некроза тканей.
На второй стадии пациенты чаще всего обращаются к врачу. Трофической язве на этой стадии характерен неприятный гнилостный запах, появление больших некротических масс, ткани вокруг очага поражения имеют признаки сильно выраженного воспалительного процесса. На этом этапе рекомендовано очищение раны, включающее в себя механический и дезинфицирующий методы. Место поражения промывают, хирургическим путем удаляют некротическую ткань, затем накладывается ранозаживляющая повязка повязка.
После полного очищения начинается этап заживления, язва напоминает открытую рану, кровоточащую при любом, даже легком травмировании ткани. На этом этапе используют различные мази и повязки для скорейшего заживления раны.
Последней стадией заживления трофической язвы является полная эпителизация тканей.
Существует множество повязок, используемых на разных стадиях лечения трофических язв, так, например, на этапе заживления трофической язвы используют Протеокс-ТМ, повязку, не только стимулирующую заживление раны, но и очищающую ее от оставшихся некротических тканей. Также используют антимикробные и обезболивающие повязки ПараПран, противовоспалительные повязки ВоскоПран и сорбирующие повязки ВоскоСорб от компании Биотекфарм, использующиеся на этапе очищения раны от некроза. Существуют и готовые наборы со всеми видами повязок для разных стадий трофической язвы, например, набор перевязочных средств для местной терапии трофических язв «Все заживет».
Трофическая язва, несомненно, тяжкий симптом. Однако не следует забывать, что это именно симптом заболевания – то, на что стоит обратить первостепенное внимание. Появления трофической язвы можно избежать, заметив первые минимальные симптомы заболевания, которые впоследствии могут стать причиной данного типа язвы. В этом случае своевременное оказание помощи исключит возможность встречи с этим опасным недугом.
Трофические язвы — глубокие гнойно-некротические кожные повреждения конечностей, незаживающие более 1,5 месяца. Чаще поражаются стопы и голени. Размеры язвы колеблются в широких пределах: от 1 см в диаметре до раневой поверхности, занимающей всю поверхность икры.
Эта патология не является самостоятельной нозологической формой. Она развивается как осложнение некоторых заболеваний, отличается упорным течением и часто излечивается только хирургическим путем.
Причины
Язвы формируются на фоне тканевой гипоксии, обусловленной нарушениями микроциркуляции, обмена веществ и иннервации тканей. Кожные покровы становятся очень уязвимыми, и даже поверхностные микроповреждения приводят к образованию плохо заживающего глубокого дефекта.
Попадание вторичной инфекции и застой крови способствуют накоплению токсинов в пораженной области, что ускоряет развитие некроза и прогрессирование патологии.
От чего появляются трофические язвы на ногах? Эти нарушения могут развиться на фоне неблагоприятного воздействия различных причин.
Существуют внешние факторы, способные спровоцировать формирование язвенного дефекта. К ним относятся следующие повреждения кожных покровов:
- рана (расчесы, порезы, ушибы);
- обморожение;
- термические или химические ожоги;
- хронические воспалительные и аллергические кожные заболевания (фурункулез, экзема, дерматит);
- радиоактивное поражение кожи;
- пролежни при продолжительной неподвижности пациента.
Причинами трофической язвы на ноге могут быть осложнения следующих заболеваний:
- хроническая сосудистая недостаточность — варикозное расширение вен, тромбофлебит, нарушения артериального кровообращения вследствие стенозирующих процессов;
- эндокринологическая патология — сахарный диабет, ожирение;
- артериальная гипертензия;
- лимфостаз любой этиологии;
- аутоиммунные болезни;
- иммунодефицитные состояния, в том числе ВИЧ-инфекция;
- поражения ЦНС — травмы головного или спинного мозга, инсульты, дегенеративные заболевания нервной системы;
- инфекционная патология (туберкулез, сифилис);
- болезни крови;
- отравления мышьяком, хромом и тяжелыми металлами.
Часто специалисты констатируют сочетание внешних и внутренних факторов, которые привели к образованию трофической язвы.
Симптомы
Как начинается трофическая язва? У человека появляются жалобы на быструю утомляемость при ходьбе, ощущение тяжести в ногах при незначительных нагрузках, сохраняющееся в покое. Возникает зуд кожи, чувство жжения, ползания мурашек в области стопы или голени, судороги в икроножных мышцах, особенно по ночам.
При осмотре доктор обнаруживает следующие начальные признаки трофической язвы:
- пастозность мягких тканей нижних конечностей;
- уплотнение, огрубление кожи пораженного участка;
- изменение цвета кожных покровов в области поражения — растущее пятно сероватого или сине-фиолетового цвета, напоминающее гематому с глянцевым оттенком;
- повышение чувствительности на участке формирования язвы, острая боль при легком прикосновении к нему;
- могут быть серозно-слизистые выделения на коже в области пятна.
При незначительной травме, перегрузках, нервном переутомлении заболевание быстро прогрессирует. В центре пятна формируется участок атрофии эпидермиса белесоватого цвета, появляется кровянистое отделяемое.
Симптомы трофической язвы в разгар болезни следующие:
- выраженный отек голени или стопы; подробнее про отек ног→
- наличие язвенного поражения, склонного при отсутствии лечения быстро увеличиваться и углубляться;
- кровянисто-гнойные выделения с неприятным запахом;
- мучительные боли в ногах, усиливающиеся при нагрузках и по ночам, ограничивающие двигательную активность;
- нарушения общего состояния (лихорадка, озноб, утомляемость, плохой аппетит).
Язвы классифицируются в зависимости от причины, вызвавшей их образование.
Венозная трофическая язва встречается у 8 пациентов из 10. Причиной служит застой из-за нарушений венозного кровообращения. Трофическая язва голени чаще всего формируется в нижней трети на внутренней поверхности ноги.
Артериальные
Фоном развития патологии у 20% пациентов являются облитерирующие заболевания артерий нижних конечностей. Стеноз артерий приводит к ишемии и некрозу мягких тканей ног. Провоцирующими моментами чаще всего являются травмы или переохлаждение конечностей, использование неудобной обуви.
Особенности такого вида трофических язв: чаще всего встречается в пожилом возрасте, человек испытывает затруднения при ходьбе по лестницам и ощущение холода в ноге.
При осмотре — нога холодная. Чаще всего обнаруживаются маленькие язвочки с явлениями нагноения в области пятки, большого пальца и по наружной поверхности стопы. Они имеют овальную форму, плотные края, кожа вокруг них приобретает желтый оттенок.
Диабетические
Трофическая язва стопы — частое осложнение сахарного диабета. Характерная локализация — большой палец или травмированные натоптыши в области подошвы. Развивается при диабетической ангиопатии на фоне резких колебаний уровня глюкозы в крови.
Характерные признаки: снижение чувствительности в ногах, угасание сухожильных рефлексов, быстрое увеличение дефекта в размерах, склонность к развитию некроза, резистентность к терапии.
Нейротрофические
При поражении центральной нервной системы язвы расположены в области пяток, на подошвах.
Особенности нейротрофических язв: небольшой размер и значительная глубина ранок (вплоть до кости), обильные гнойные выделения с неприятным запахом при отсутствии болей.
Гипертонические
Встречаются редко, обычно у пожилых женщин на фоне длительно протекающей артериальной гипертензии.
Отличаются замедленным формированием, причем сразу на двух ногах, выраженным болевым синдромом, высокой частотой гнойных осложнений.
Инфекционные
Формируются на голенях при запущенных кожных болезнях на фоне антисанитарии и наслоении вторичной гнойной инфекции. Особенности: полукруглая форма, незначительные размеры и глубина.
Какой врач занимается лечением трофических язв?
Трофические язвы при варикозе лечат флебологи и сосудистые хирурги. Пациенты с наличием язвенных кожных дефектов любой этиологии подлежат обязательной госпитализации, так как эффективное лечение трофической язвы возможно только в стационарных условиях. Необходима комплексная терапия и динамическое наблюдение.
Лечить трофическую язву в домашних условиях допустимо только на самой ранней стадии.
Диагностика
Трофическая язва на ноге сопровождается специфическими жалобами и имеет характерный вид при осмотре. Основная задача специалистов — выяснить причину заболевания. Только установив этиологию язвенного поражения, можно назначить адекватную терапию.
Проводятся следующие диагностические мероприятия:
- Тщательный сбор анамнеза и осмотр терапевта, флеболога, ангиохирурга.
- Лабораторные методы: общие анализы крови и мочи, в том числе с определением уровня глюкозы, биохимический анализ крови, иммунограмма, бактериологический анализ язвенных выделений и биопсия взятых биоматериалов.
- Инструментальные методы: реовазография, ангиография с введением контрастных веществ, УЗИ сосудов нижних конечностей (доплерография, дуплекс-исследование).
Лечение
Главные направления терапии — воздействие на основное заболевание, борьба со вторичной инфекцией, стимуляция заживления язвенной поверхности.
Лечение трофической язвы зависит от следующих факторов:
- причина появления и длительность существования кожного поражения;
- возраст пациента и наличие сопутствующих заболеваний;
- размер и глубина кожного дефекта, темпы роста;
- состояние кожи вокруг язвы.
Как вылечить трофическую язву? Терапия чрезвычайно сложная, комплексная и длительная. Она чаще расценивается как подготовка к операции, так как консервативные методы не слишком действенны.
Если операция пациенту противопоказана по каким-то причинам, цель терапии — не допустить увеличения и углубления дефекта кожи.
В стационаре пациенту с трофической язвой обеспечивается постельный режим, пораженная конечность должна находиться в приподнятом положении для улучшения крово- и лимфообращения.
Консервативное
Универсальное лекарство от трофических язв, одинаково эффективное при всех видах болезни, не разработано. Лечение трофической язвы на ноге включает прием препаратов различных фармакологических групп.
Чем лечить трофические язвы при варикозе? Специалисты назначают комплексную терапию, цель которой остановить воспаление и некротизацию тканей, стимулировать процессы заживления.
Применяются медикаменты из следующих групп:
- Вазоактивные препараты, в том числе флеботоники (Троксевазин, Детралекс) и антиагреганты (Тромбо-асс). Способствуют расширению сосудов, улучшению микроциркуляции, укреплению стенок вен и уменьшению венозного застоя. Подробнее про Тромбо асс и его аналоги→
- Инфузионная терапия — растворы гемодеза, реополиглюкина при явлениях интоксикации.
- Противоотечные средства. Применяются по строгим показаниям, периодически, под наблюдением врача. При их приеме проводится мониторинг содержания электролитов в крови.
- Антибиотики — при инфекционной этиологии язвы или наслоении вторичной инфекции. Назначают после выделения патогенного агента из язвенного секрета и выяснения его чувствительности к антибиотикам различных групп.
- Противовоспалительные средства — при наличии гнойного отделяемого, воспалительной реакции окружающих тканей и выраженного болевого синдрома.
- Гипосенсибилизирующие препаратыуменьшают выделение секрета язвенной поверхностью.
Эти же лекарственные средства в разных комбинациях используются при лечении трофических язв любой этиологии.
В период регенерации назначается антиоксидантная, метаболическая и иммуностимулирующая терапия — инъекции мексидола, актовегина, аскорбиновой кислоты, витаминов группы B.
Для заживления трофических язв применяется физиотерапия. Используется УВЧ для усиления противовоспалительного воздействия лекарств, электрофорез с растворами ранозаживляющих, противовоспалительных и сосудистых препаратов. Практикуется лечение лазером, уменьшающее боль и воспаление.
В период регенерации и в послеоперационный период рекомендуют ультрафиолетовое облучение, озонотерапию, грязелечение, гипербарическую оксигенацию, плазмафарез.
Лечение трофической язвы нижних конечностей дополняет правильное питание. Чтобы избежать нарастания отечности в ногах, человек должен есть больше овощей и фруктов, контролировать количество потребляемой жидкости, исключить соленую, острую, маринованную пищу. При сахарном диабете пациенты питаются в соответствии с рекомендациями эндокринолога и регулярно контролируют уровень глюкозы в крови.
Местная терапия
Для очищения раны от гноя и омертвевших тканей ее обрабатывают дезинфицирующими средствами.
Используются следующие антисептики:
- водный раствор хлоргексидина;
- 3% раствор борной кислоты;
- раствор марганцовки определенной концентрации;
- Риванол;
- ферменты.
Чем обрабатывать трофические язвы на ногах после очищения их от гноя? Для заживления и ускоренного рубцевания кожных дефектов применяют лечебные мази: Солкосерил, Эбермин, Актовегин. Эффективно использование специальных повязок и губок с антибактериальным, антисекреторным и ранозаживляющим действием (Аллевин, Альгипор, Гешиспон).
Обязательным является применение эластичного бинта, который заменяют по мере необходимости несколько раз в день. Он не только защищает пораженный участок от проникновения вторичной инфекции и травмирования, но и способствует уменьшению отечности.
Хирургическое вмешательство
Окончательно вылечить трофическую язву на ноге можно с помощью хирургии. Для того чтобы операция прошла успешно, необходимо провести грамотную подготовку пациента к предстоящему вмешательству, добиться улучшения самочувствия, стабилизации общего состояния и начала заживления раневой поверхности.
В ангиохирургии разработаны следующие методы:
- шунтирование при сосудистых заболеваниях;
- удаление участка вены с варикозными узлами (флебэктомия).
При наличии большой по размеру и глубокой язвы производится трансплантация кожного лоскута.
Народные методы
Вопрос о возможности амбулаторного лечения трофических язв решается только лечащим специалистом. При небольшой длительности болезни, маленьких единичных язвочках, находящихся на этапе регенерации, пациент может использовать народные рецепты в качестве дополнения к основной терапии.
Как лечить трофическую язву в домашних условиях? Очищают раневую поверхность от остатков гноя, так как он замедляет заживление. Для этого используются отвары аптечной ромашки, чистотела, череды, календулы.
После промывания язвы с разрешения врача накладывают аптечные мази, способствующие снятию воспаления и заживлению, в том числе мазь Вишневского, ихтиоловую мазь.
Можно обработать язвенный дефект соком золотого уса, сделать повязку с мазью, приготовленной на основе прополиса, окопника, арники. Применяют компрессы с порошком листьев татарника, золотого уса, коры ивы или дуба, которые можно оставлять на ночь.
Надеяться только на народную медицину нельзя, отказ от комплексного стационарного лечения может привести к опасным для жизни последствиям.
Осложнения
В запущенных случаях и при отсутствии активного лечения появляется целый ряд опасных осложнений:
- наслоение вторичной инфекции, возможно рожистое воспаление;
- кожные заболевания (экзема);
- поражение костно-суставной системы (артриты, периоститы, контрактуры);
- сосудистые нарушения (тромбоз);
- кожные новообразования (в крайне запущенных случаях).
Чем опасно заболевание?
Язвы опасны быстрым прогрессированием при тяжелом течении основной болезни. При этом они не только увеличиваются в размерах, но и становятся многочисленными, могут сливаться в обширную раневую поверхность.
Также эту патологию отличают следующие особенности:
- склонность к рецидивирующему течению;
- устойчивость ко всем методам терапии, кроме хирургического лечения, которое может иметь противопоказания;
- возможность развития сепсиса — при язвах венозного происхождения, гангрены — при диабетических язвах, остеомиелита.
Профилактика
Главное правило — своевременно обращаться к врачам при появлении проблем со здоровьем. После операции для исключения рецидивов важно придерживаться следующих рекомендаций:
- ежегодное санаторно-курортное лечение в санаториях соответствующего профиля;
- здоровый образ жизни, сбалансированное питание и контроль массы тела;
- исключение длительных статических нагрузок, переохлаждения ног;
- регулярное использование лечебного трикотажа и эластичного бинта, особенно при ходьбе;
- постоянный контроль уровня глюкозы в крови при сахарном диабете;
- использование удобной обуви, костылей и палочки для уменьшения нагрузки на стопы;
- курсовой прием рекомендованных врачом витаминно-минеральных комплексов для укрепления иммунной системы, антитромботических средств.
Язвы формируются как тяжелые осложнения запущенных болезней. Они неуклонно прогрессируют, устойчивы к терапии и часто рецидивируют. Только некоторые разновидности на начальных этапах развития можно лечить терапевтическими методами. Вылечить дома, не прибегая к врачебной помощи, невозможно.
Прогноз зависит от своевременного обращения, тщательного выполнения врачебных рекомендаций и лечения основного заболевания, на фоне которого появилась язва.
Долго незаживающие раны, связанные с нарушением кровообращения, в медицине называются трофическими язвами. Наиболее часто трофические язвы поражают ноги, особенно от стоп до коленей.
Нарушение кровоснабжения нижней части туловища приводит к застою крови, от чего и бывают трофические язвы.
Причиной заболевания служат:
- застой венозной крови;
- венозная недостаточность;
- ухудшение артериального кровообращения вследствие гипертонии;
- сахарный диабет;
- пролежни;
- экзема;
- обморожения;
- ожоги;
- васкулиты;
- отравления химическими веществами, в частности, хромом и мышьяком.
Трофические язвы возникают как осложнение уже имеющихся проблем со здоровьем, это своеобразный сигнал о нарушении защитных свойств кожи и ослаблении иммунитета.
Если язва образуется не на раневой поверхности, а в результате нарушения кровообращения, можно наблюдать постепенное изменение кожных покровов. Они темнеют, приобретают темно-красный цвет с синим отливом, в этом месте появляется отек, кожа натягивается и блестит, как лакированная. Возможно появление лимфатической жидкости в виде капелек. Малейшая травма — ссадина, легкий ушиб, — и целостность покровов нарушается.
Рана сопровождается зудом, болью, жжением. Лечению трофические язвы поддаются с трудом. Прогноз зависит от общего состояния больного и течения основной болезни.
Виды трофических язв
Различают три вида:
- Венозные.
- Артериальные.
- Язвы при сахарном диабете.
Симптомы трофических язв отличаются при разных видах заболевания:
- Венозные. Место локализации — голень в самом низу с обеих сторон, немного выше косточек. Возникает при хронической венозной недостаточности, закупорке и воспалении вен. Ноги отекают, в больном месте ощущается жар. Кожа утолщается, становится блестящей, темнеет. На поверхности кожи образуются фиолетовые пятна, отчетливо проступают вены. Выделяется на поверхность кожи лимфа. Небольшой травмы достаточно, чтобы запустить патологический процесс. Рана обычно имеет форму круга с изъязвлениями неровными краями. Из раны сочится сукровица и гной, если присоединилась инфекция. Без надлежащего лечения рана становится глубже, поражаются икроножные мышцы, сухожилия и кости. Появляется опасность остеомиелита. Боли прогрессируют. Приподняв ногу выше уровня тела (в положении лежа), можно на начальной стадии болезни добиться стихания болевых ощущений.
- Артериальные. Поражают стопу, большой палец и пятку. Образуются при сужении артерий, из-за чего нарушается доставка питания и кислорода в прилегающие ткани. Хроническое голодание приводит к некротическим изменениям в тканях кожи и мышц. Образуются очень болезненные язвы небольшого размера. Провоцирует появление этого вида язв ношение тесной обуви, атеросклероз, эндартериит, гипертония. Появление трофических язв свидетельствуют о критической ишемии.
- Трофические язвы при сахарном диабете. Поражают чаще всего пальцы (большой палец) ноги и стопы. Язвы часто бывают несоразмерно участку поражения большими и глубокими. Сахарный диабет характеризуется усилением атеросклероза, повреждением сосудов, ослаблением иммунитета. Все это приводит к специфическим изменениям в тканях организма. Незначительный ушиб, потертость на ноге, вросший ноготь становятся началом заболевания.
Осложнения
Запущенные трофические язвы могут вызвать осложнения. Возможные осложнения:
- микробная экзема;
- рожа;
- пиодермия (гнойное воспаление кожи, вызванное гноеродными бактериями — стрептококками и пр.);
- вторичное инфицирование;
- лимфаденит (воспаление лимфоузлов);
- лимфангоит (воспаление сосудов лимфатических узлов);
- мацерация кожи в области язвы (нарушение целостности кожи, исчезновение);
- преобразование тканей в злокачественные;
- сепсис;
- остеомиелит;
- гангрена.
Заживление раны происходит медленно и делится на две стадии: очищения и заживления.
На стадии очищения язву очищают от гнойного и некротического содержимого, обрабатывают антисептиком. На кожу вокруг раны наносят антисептические и антибактериальные мази. На стадии заживления рана уменьшается с краев, постепенно затягиваясь из краев к центру.
Признаком заживления трофической язвы является начавшееся очищение,уменьшение в размерах, грануляция раны, покрытие ее тонкой красной кожей.
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