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Свечи с индометацином и алкоголь

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17 августа 2019

Краткое описание

Индометацин относится к негормональным препаратам, действие которых направлено против воспаления. Обладает способностью уменьшать воспаление, снимать боль, жар.

Эффективность препарата обеспечивается блокированием цепочки биохимических реакций, приводящих к воспалению. При суставных болях Индометацин снимает боль, уменьшает отечность суставов, облегчает их подвижность, увеличивает амплитуду движений.

Состав и форма выпуска

Свечи индометацин

Активное действующее вещество: Индометацин производится в виде свечей белого либо желтовато-белого цвета. 1 свеча содержит 50 мг либо 100 мг индометацина.

Дополнительные вещества: жир твердый, кукурузный крахмал.

Упаковка: в одном блистере находится 5 свечей.

Таблетки индометацин

Активное действующее вещество: Индометацин выпускается в виде таблеток с защитной кишечнорастворимой оболочкой оранжево-желтого или оранжевого цвета, форма двояковыпуклая. Возможна мраморная поверхность, имеющая вкрапления.

На поперечном срезе различаются 2 слоя. 1 таблетка индометацина содержит 25 мг препарата.

Дополнительные вещества: картофельный крахмал, целактоза, стеарат кальция, коповидон, диоксид титана, присыпка, макроголь 6000, желтый краситель Е 110.

Упаковка: в одном блистере находится 30 таблеток.

Мазь индометацин

Активное действующее вещество: Индометацин производится в виде однородной мази 10% для наружного применения желто-коричневого цвета. В 1г мази содержится 100 мг индометацина.

Дополнительные вещества: холестерин, спирт стеариловый, димексид, белый воск, животный воск, парафин.

Упаковка: туба алюминиевая 40 гр.

Фармакодинамика

Индометацин в виде свечей обеспечивает снижение или прекращения боли при ревматизме (суставные боли без движения либо в движении, снятие оцепенения и неподвижности суставов поутру, уменьшение отечности суставов, увеличение амплитуды движений. При послеоперационных и посттравматических воспалениях, способствует снятию боли, уменьшению отека).

Индометацин в виде таблеток является негормональным средством, предупреждающее воспаление. Оказывает также анальгезирующее действие, снимает боль. Способ воздействия объясняется блокирование действия фермента, который участвует в синтезе вызывающих воспаление веществ. Лекарство обеспечивает уменьшение боли, особенно суставной в покое и динамики, способствует увеличению амплитуды движений.

Замедляет склеивание тромбоцитов, что препятствует образовании сосудистых тромбов. объединение клеточных фрагментов кровотока.

Результат уменьшения воспаления проявляется через 7 дней с начала приема препарата.

Индометацин в виде мази представляет негормональное лекарство, направленное на предупреждение боли. Обладает способностью притуплять боль, снимать воспаление, жар. Индометацин относится к группе алкалоидов. Воздействие препарата объясняется замедлением объединения ферментов и иных воспалительных факторов. При суставных болезнях препарат уменьшает и локализует боль, снимает отечность, увеличивает амплитуду движений.

Фармакокинетика

Усвояемость индометоцина в свечах ускоренная. При введении в толстый кишечник его эффективное использование достигает 90%. Синтез с белками плазмы крови доходит до 90%. Период полувыведения от 4ч до 9ч. Превращение в основном происходит в печени. Треть лекарства выводится нерастворенным. 70% выводятся почками, оставшаяся треть- через кишечник. При диализе удалить не представляется возможным. Распространяется в грудное молоко.
Индометацин в виде таблеток ускоренно используется из ЖКТ.

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Наибольшее содержание препарата в плазме крови замечено в течение двух часов с момента приема лекарства. Усвояемость практически полностью. Активно взаимодействует с белками плазмы крови. Время полураспада от двух до одиннадцати часов. Перерабатывается в основном в печени. Подвержен повторному всасыванию вещества в ЖКТ. Удаляется 20% в неизменной форме. Треть удаляется через кишечник, оставшаяся часть-почками.

Возможно проникновение в кровоток плаценты и плода. В суставы замечено замедленное попадание.
У пациентов с болезнями печени и почек наблюдается накапливание препарата.

Индометацин в виде мази обеспечивает локализацию очага боли и снижение боли. Способ действия препарат основан на замедлении деятельности ферментов, участвующих в объединении простаноидов. Ослабление деятельности фермента циклооксигеназы способствует уменьшению боли. В случаях заболевания суставов снимает воспаление и боль. Снижает отечность. Работоспособность суставов благодаря мази индометациновой значительно активизируется. Превосходит аспирин по эффекту противовоспалительного действия. Обезболивание наступает через 9 часос с момента применения.

Меры предосторожности

При использовании свечей индометацина необходимо проводить анализ крови, а также следить за состоянием печени и почек. В период лечении не рекомендуется вождение автотранспорта и выполнение работ, требующих исключительно повышенной концентрации внимания.

При приеме индометацина в таблетках не рекомендуется водить автотранспорт и не заниматься опасной деятельностью, требующей концентрации внимания по причине проявления нежелательных побочных эффектов в виде головокружения, слабости.

Научно не доказано влияние препарата на управление транспортным средством.

Показания к применению

Индометацин в виде свечей назначается как противовоспалительное средство при заболевании суставов – артритов, ревматизме. В качестве дополнительного лекарства при лечении инфекций и воспалений уха, горла, носа, воспалении придатков матки, воспалении предстательной железы, воспалении мочевого пузыря, менструальных болях, болезнях периферических нервов, мигрени, зубной боли.

Индометацин в таблетках применяют при различных артритах,особенно связанных с ревматизмом, болезни Бехтерева, артрозах, при бурсите, миозите, послеоперационных и посттравматических, стоматологических отеках и воспалениях. А также в комплексе при лечении лор-органов, воспалении предстательной железы и мочевого пузыря.

Мазь индометациновая используется при воспалении сухожилий после травм, растяжении связок, мышц, при бурсите, воспалении сухожильного влагалища, при мышечной боли, радикулите, прострелах в пояснице, остеоартрозе, артрите, остеохандрозе.

Как лечиться индометацином?

Свечи с содержанием индометацина применяют ректально. Рекомендуется заблаговременно очистить кишечник. Дозировка для взрослых составляет 1 свеча (50мг) до трех раз в сутки, в моменты обострения подагры- до 200 мг в сутки.

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Индометацин в таблетках рекомендуется принимать во время приема пищи либо после, лучше запивая молоком. Для взрослых суточная доза составляет 1 таб/ 2-3 раза. Иногда суточную дозу увеличивают до 2 таб/ 3 раза. Увеличение дозы постепенное, с оценкой результата в течение двух недель. При эффективности нужной терапию продлевают до месяца в необходимой дозе. Наибольшее количество препарат в сутки составляет 200 мг ( 8 таблеток), в случае длительного применения суточная доза 75 мг ( 3таблетки).

Для детей в возрасте от 14 лет доза составляет 2мг на 1кг массы тела. Суточный прием с интервалом 6-8 часов.
Стандартное назначение препарата на длительный срок. Если лекарство перестать принимать раньше, возможен рецидив заболевания. Длительность лечения определяется лечащим врачом.

Индометациновую мазь применяют наружно. Ее втирают на участки кожи 3-4 раза в сутки. Для лучшего облегания используют специальные повязки .Доза препарата для взрослых составляет не более 15см, получаемых из тубы , детская доза – 7,5см. Длительность лечения 1 месяц. Продолжение терапии устанавливается врачом.

Побочные действия

  • рвота
  • вспучивание
  • жжение в пищеводе
  • похудание
  • понос
  • боли в животе
  • печеночная недостаточность
  • дисбактериоз кишечника
  • слабость
  • потеря сознания
  • нарушение сна
  • чрезмерная активность
  • депрессия
  • гипертония
  • нарушение сердечной деятельности
  • почечная недостаточность
  • нефрит
  • ослабление слуха
  • ослабление зрения
  • болезни глаз
  • сыпь
  • чесотка
  • отечность
  • спазм бронхов
  • шок

Индометацин и алкоголь

Индометацин и алкоголь не совместимы.

При использовании лекарства употребление алкоголя строго противопоказано.

Противопоказания

  • индивидуальная непереносимость препарата,
  • воспаление глаз и терапия негормональными препаратами,
  • язвы желудка и двенадцатиперстная кишка,
  • уменьшение количества тромбоцитов,
  • появление венозных тромбозов,
  • воспаление толстой и тонкой кишок,
  • болезни печени и почек,
  • болезни сердца,
  • болезни глаз,
  • органов слуха,
  • болезни вестибулярного аппарата,
  • болезни поджелудочной железы,
  • эпилептические припадки,
  • болезнь Паркинсона,
  • беременность,
  • период лактации,
  • возраст до 14 лет.

При беременности

Индометацин не рекомендуется в период беременности. В период лечения нужно приостановить вскармливание грудным молоком.

Особые указания

В период лечения индометацином не рекомендуется вождение транспортных средств и занятия работой, требующих исключительной концентрации внимания.

Индометацин способен уменьшать функции препаратов на внутренние органы при одновременном использовании, увеличивать риск токсичности на органы, увеличивать возможность болезней и последствий, вот почему это важно учитывать при использовании препарата.

Взаимодействие

Признаки передозировки- тошнота, рвота, мигрень, потеря сознания, памяти, ориентации, судороги.
Терапия- прекращение приема препарата, промывание желудка, прием активированного угля 30 мг.

При диализе удалить невозможно.

Не существует противоядия.

Аналоги

  • Индометацин-Акри
  • Метиндол
  • Метиндол Ретард
  • Индоцид
  • Индотард
  • Индометацин-Биосинтез
  • Индометацин-Альтфарм
  • Индометацин-Софарма
  • Индометацин 50 Берлин-Хеми
  • Мовимед
  • Индоколлир
  • Индовис
  • Индобене
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Отзывы

Юля
Попробовала по рекомендации гинеколога лечение свечами индометацин дважды в день. На другой день появилась сильная мигрень, во сне- кошмары. В ушах- шум. Затем началась рвота. Прием препарата прекратила.

Любовь
Принимала свечи индометацин. Помогли снять боль. Но взамен- я стала нервной, появилось головокружение. Эти признаки я заметила через две недели после приема препарата.

Галина
Моя попытка лечения артрита индометацином свелась к блокированию боли.

В таблице указана возможность совместного употребления спиртных напитков и препарата Индометацин — через сколько времени и когда, принимать препарат

ФОРМЫ ПРИЕМ ЛЕКАРСТВА
МОЖНО НЕЛЬЗЯ

• за 24 часа до употребления алкоголя мужчинам.

• за 32 часа до употребления алкоголя женщинам.

• через 14 часов после употребления алкоголя мужчинам.

• через 20 часов после употребления алкоголя женщинам.

• через 15 дней если был курс лечения, мужчинам и женщинам.

[!] чтобы избежать возможных рисков угрозы здоровью, откажитесь от спиртного на весь период лечения.

• опасно вместе с алкоголем, мужчинам и женщинам.

• ни при каких условиях на любых сроках беременности.

• ни при каких условиях во время курса лечения, мужчинам и женщинам.

При возможной не совместимости индометацин повлияет на нарушения сердечного ритма — брадикардия или тахикардия, проявления острой сердечной недостаточности, иногда — ортостатическая гипотензия.

• Перестать дальше употреблять спиртное.

• Последующие 4 часа пить больше воды.

• В аннотации к лекарству прочтите пункт — противопоказания, и следуйте им.

• Если лекарство принималось курсом лечения, алкоголь противопоказан к применению от 3 дней до 1 месяца (в зависимости от указаний лечащего врача).

• Не имеет значение какая форма индометацина принимается с алкоголем, влияние окажет как таблетка так и мазь.

• Если подобное происходит в первый раз, риск навредить здоровью — минимален.

• Обратитесь к врачу за дополнительной помощью и консультацией.

— В расчетах таблицы принят усредненный показатель выпитого (средняя степень опьянения), рассчитанный пропорционально массе тела в 60 кг.

— К спиртному, способному подействовать на препарат, отнесено: пиво, вино, шампанское, водка и др. крепкий напиток.

— Даже 1 доза спиртного, может повлиять на лекарство в организме.

За 1 дозу выпитого для разных напитков , принято считать:

Срочно. Лучшие врачи.
Специальные
предложения.

  • Проверьте свои симптомы;
  • Узнайте о возможных заболеваниях;
  • Предупредите болезнь.

Проверить симптомы

  • Что означают эти цифры?
  • А странные слова и буквы?
  • Не выходя из дома.

Расшифровать анализы

Срочно. Лучшие врачи.
Специальные
предложения.

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