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Мази улучшающие кровообращение в тканях

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17 августа 2019

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Периферическое кровообращение — кровоток в мелких артериях, артериолах, капиллярах, посткапиллярных венулах, артериовенулярных анастамозах, венулах и мелких венах. В результате структурных или функциональных нарушений в них могут возникнуть следующие расстройства кровообращения:

1) Артериальная гиперемия — увеличение наполнения тканей артериальной кровью. Проявляется покраснением, потеплением кожи над местом поражения. Развивается при действии химических веществ, токсинов, продуктов воспаления, при лихорадке, при аллергиях.
2) Венозная гиперемия — увеличение кровенаполнения органа или ткани в результате затрудненного оттока крови по венам. Проявляется синюшностью тканей. Причины: сдавление вен или их закупорка, ослабление сердечной мышцы, затруднение кровотока в легочном круге кровообращения.
3) Ишемия — ограниченное или полное нарушение снабжения артериальной кровью. Причины: сдавление, закупорка или спазм артерий. Проявляется болями из-за накопления в условиях сниженного поступления кислорода к тканям недоокисленных продуктов обмена — медиаторов воспаления.
4) Стаз — замедление и остановка крови тока в капиллярах, мелких артериях и венах. Причины: высокие или низкие температуры, отравления ядами, высокие концентрации поваренной соли, скипидар, горчичное масло, токсины микроорганизмов.
5) Тромбоз — образование сгустков крови, состоящих из ее элементов и препятствующих нормальному кровотоку. Проявляется отечностью и синюшностью тканей.
6) Эмболия — закупорка сосудов инородными телами (микроорганизмами, каплями жира) или газами.

К клиническим формам нарушения периферического кровообращения можно отнести облитерирующий эндартериит, тромбофлебиты и флеботромбозы, тромбэмболию легочной артерии, хронические нарушения мозгового кровообращения, варикозную болезнь нижних конечностей, глазные болезни ишемического происхождения, болезнь Рейно.
Жалобы, которые предъявляют пациенты разнообразны. Обратиться к специалисту стоит, если:

— беспокоят боли в ногах в конце дня, при ходьбе или долгом стоянии; отеки и синюшность нижних конечностей;
— есть головные боли, шум в ушах, снижение слуха, нарушения сна, расстройства памяти, неустойчивость при ходьбе, онемение в руке или ноге, расстройства речи, нарушения глотания;
— имеется зябкость рук, боли в пальцах рук при нагрузке, побеление кистей при охлаждении;
— наблюдается снижение остроты зрения или выпадение полей зрения.

Средства для улучшения периферического кровообращения

К препаратам, улучшающим периферическое кровообращение относятся:
1) Препараты, улучшающие микроциркуляцию. Ангиопротекторы. Нормализуют проницаемость капилляров, улучшают обменные процессы в стенках сосудов. Курантил (дипиридомол), персантин, трентал, флекситал, вазонит, радомин, пентоксифиллин, докси-хем.
2) Препараты низкомолекулярного декстрана. Препараты привлекают в кровяное русло дополнительные объемы крови из межклеточного пространства. Улучшают текучесть крови. Реомакродекс, реополиглюкин.
3) Препараты простогландина Е1. Улучшают кровоток, микроциркуляцию, эластичность эритроцитов. Повышают противосвертывающую активность крови. Расширяет сосуды, обеспечивая снижение периферического сопротивления сосудов и артериальное давление. Вазапростан.
4) Блокаторы кальциевых каналов. Улучшают микроциркуляцию сосудов головного мозга, обладают церебропротекторным эффектом. Используются преимущественно при нарушениях мозгового кровообращения. Кордафен, кордафлекс, нимотоп, стугерон, циннаризин, адалат, арифон, гриндеке, брейнал, диакордин, кордипин, кортиазем, логимакс, лаципил, нафадил, немотан, нифекард, стамло, форидон, цинедил, циннасан, плендил, норвакс.
5) Миотропные спазмолитики. Препараты этой группы способны расширять сосуды, увеличивая мозговой кровоток. Проявляют высокую эффктивность при спазмах сосудов головного мозга. При порпжении сосудов атеросклерозом менее эффективны. К недостаткам препаратов(кроме кавинтона) можно отнести феномен обкрадывания — расширение преимущественно неповрежденных сосудов с уменьшением кровотока по голодающим участкам мозга.
Препараты этой группы обладают способностью расширять сосуды, усиливая мозговой кровоток. Как правило, они высокоэффективны при спазмах мозговых сосудов, но при развитии склеротических процессов способность мозговых сосудов к расслаблению снижается и, следовательно, снижается и эффективность действия сосудорасширяющих
средств. Кроме того, эти препараты могут вызывать феномен внутримозгового «обкрадывания» (отсутствует у Кавинтона), когда под влиянием сосудорасширяющих происходит преимущественное расширение неповрежденных сосудов и перераспределение кровотока в пользу здоровых областей мозга.
Но-шпа, но-шпа форте, дротаверин, галидор, кавинтон, мидокалм, никошпан, спазмол, эуфиллин.
6) Фитопрепараты. Препараты из натурального сырья. В отличие от синтетических препаратов эффект от этой группы развивается более медленно, лечебное действие оказывает комбинация соединений. Эффективны при заболеваниях мозговых сосудов и облитерирующих заболеваниях нижних конечностей. Билобил, танакан
7) Биофлавоноиды. Обладают способностью улучшать текучесть крови за счет повышения эластичности эритроцитов. Нормализуют капиллярный кровоток. Венорутон, троксевазин, антоксид.
8) Ганглиоблокаторы. Расширяют артериолы, венулы, мелкие вены, за счет чего достигается снижение артериального давления. Способствуют перераспределению крови в сосуды нижних конечностей. Димеколин, камфоний, пахикарпин, пентамин, пирилен, темехин,
9) Альфа-адреноблокаторы. Вызывают расширение сосудов кожи, почек, кишечника, особенно артериол и прекапилляров, снижая их общее сопротивление, улучшая кровоснабжение периферических тканей. Сермион, нилогрин, празозин, пирроксан, фентоламин.
10) Стимуляторы допаминовых рецепторов. Сосудорасширяющее действие осуществляется за счет стимуляции допаминовых рецепторов, которые имеются в том числе в сосудах нижних конечностей. Увеличивает кровоток в сосудах нижних конечностей. Проноран.

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Так как заболевания, в основе которых лежит нарушение периферического кровотока, приводят без своевременного лечения к инвалидизации, самолечение противопоказано.

ИНСТРУКЦИЯ по медицинскому применению препарата ДИПИРИДАМОЛ DIPYRIDAMOL

Внимательно прочитайте эту инструкцию перед тем, как начать прием этого лекарства. Сохраните инструкцию, она может потребоваться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Это лекарство назначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас.

ИНСТРУКЦИЯ ПО МЕДИЦИНСКОМУ ПРИМЕНЕНИЮ ЛЕКАРСТВЕННОГО ПРЕПАРАТА Диосмин

Регистрационный номер: ЛП-005213-031218
Торговое наименование: Диосмин
Международное непатентованное наименование: диосмин
Лекарственная форма: таблетки, покрытые пленочной оболочкой

Обеспечение тканей кровью и поддержание в них здоровой микроциркуляции – одна из важнейших задач организма, от которой зависит нормальное функционирование ее органов и систем. Учитывая тот факт, что сердечно-сосудистая патология занимает лидирующее положение в структуре заболеваемости и смертности, сосудистые препараты для улучшения кровообращения сегодня нашли широкое применение у врачей совершенно разных специальностей. Это семейство лекарственных средств включает множество групп и продолжает пополняться новыми современными лекарственными формами.

Механизм действия

Препараты, улучшающие кровообращение, оказывают свое действие следующими способами:

  • Воздействие на вегетативную нервную систему (адреноблокаторы);
  • Прямое действие вещества на гладкую мускулатуру сосудов (спазмолитики);
  • Снижение концентрации ионов Кальция (антагонисты кальциевых каналов);
  • Угнетение биологических факторов (например ангиотензинпревращающего фермента), повышающих тонус сосудов и артериальное давление (ингибиторы АПФ) и др.

Снижение вязкости крови, которое осуществляется посредством:

  • Уменьшения тромбообразования за счет угнетения свертывающей и потенцирования противосвертывающей системы крови (антикоагулянты);
  • Снижения способности клеток крови к склеиванию (антиагреганты);
  • Увеличение жидкой части крови (декстраны).
  1. Укрепление сосудистой стенки (витамины, рутин, венотоники);
  2. Антиоксидантное, антигипоксическое действие (ноотропы, никотиновая кислота);
  3. Снижение уровня липидов крови, профилактика атеросклероза (статины).
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Надо учитывать, что каждое семейство лекарств может оказывать свое действие как на кровообращение в целом, так и изолированно (артериальное или венозное русло), быть тропным к различным по калибру сосудам (артерии, вены, венулы, капилляры) или оказывать лечебный эффект применительно к определенным органам и системам (сердце, головной мозг, сосуды конечностей).

Показания

В целом, основными состояниями, при которых обосновано применение сосудистых медикаментов являются:

  1. Ишемия сердечной мышцы;
  2. Нарушения мозгового кровообращения любого генеза;
  3. Облитерирующие (спастические) заболевания артерий конечностей;
  4. Варикозные изменения вен;
  5. Нарушения трофики органов и тканей при сахарном диабете и других заболеваниях.

Далее будет рассмотрены сферы применения конкретных групп препаратов:

Сосудорасширяющие препараты (вазодилататоры)

Анна Поняева. Закончила нижегородскую медицинскую академию (2007-2014) и Ординатуру по клинико-лабораторной диагностике (2014-2016).Задать вопрос>>

  • Ишемическая болезнь сердца;
  • Острая и хроническая сердечная недостаточность;
  • Артериальная гипертензия.

Антагонисты кальция (блокаторы кальциевых каналов):

  • Стенокардия и ишемия сердца;
  • Гипертоническая болезнь;
  • Болезнь Рейно (спастическая недостаточность артерий верхних конечностей);
  • Сердечные аритмии;
  • Головные боли;
  • Легочная гипертензия – высокое давление в малом круге кровообращения, отек легких.
  • Артериальная гипертензия, гипертонический криз;
  • Сердечная недостаточность;
  • Мигрень;
  • Аденома простаты.
  • Острые и хронические нарушения кровообращения;
  • Спастические головные боли, мигрени;
  • Нарушения мозгового кровообращения;
  • Спазм мускулатуры органов желудочно-кишечных и выделительной систем.

Препараты, направленные на снижение вязкости крови

  • Восполнение объема циркулирующей крови и нормализация капиллярного тока после травм, ранений, ожогов, операций;
  • Предотвращение развития шока;
  • Дезинтоксикация
  • Болезни, связанные с нарушением микроциркуляции органов зрения и слуха (потеря слуха, дистрофия и атрофия сетчатки, воспаление роговицы).
  • Тромбоз артерий при инфаркте миокарда, ишемическом инсульте, тромбоэмболии легочной артерии;
  • Тромбообразование в венах при варикозных изменениях, геморрое;
  • Синдром диссеминированного внутрисосудистого свертывания (ДВС-синдром);
  • Профилактика развития послеоперационных тромбозов.
  • Профилактика инфаркта при ишемической болезни миокарда;
  • лечение ишемического инсульта;
  • Гипертоническое заболевание;
  • Облитерирующие болезни артерий конечностей.

Ноотропные средства

  • Нарушения мозгового кровообращения;
  • Неврологические и психические расстройства (ЧМТ, снижение памяти, мигрени и др.)

Препараты никотиновой кислоты

  • Атеросклеротические изменения;
  • Облитерирующие заболевания;
  • Ишемия мозговой ткани;
  • Патология микроциркуляторного русла.

Лекарственные средства растительного происхождения

  • Нарушения мозгового кровообращения различной этиологии;
  • Органические заболевания нервной системы;
  • Головные боли.

Препараты, укрепляющие сосудистую стенку (ангиопротекторы)

  • Варикозные изменения вен;
  • Поражения мелких сосудов глаз;
  • Диабетические поражения;
  • Ревматизм;
  • Геморроидальные кровотечения;
  • Риск развития геморрагического инсульта при артериальной гипертонии.
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Противопоказания

Различаются в зависимости от группы, но к наиболее общим относят:

  • Низкое АД (гипотензия, гипотония) для средств с выраженным сосудорасширяющим действием;
  • Кровоточивость, кровотечения, нарушения свертывания крови, язвы ЖКТ — касается средств, снижающих вязкость крови.
  • Почечная и печеночная недостаточность;
  • Детский возраст, беременность, период лакткации.

Периферическое кровообращение – это беспрерывный процесс циркуляции крови в мелких венах и артериях, капиллярах, а также артериолах и венулах. К нарушению циркуляции крови приводят самые различные факторы, среди них: опухоли, травмы, болезни сердца и сосудов, болезни почек, нарушение обмена веществ и т.д.

Признаками нарушенного кровообращения могут быть: боль в ногах, отечность, изменение цвета конечностей, головные боли, проблемы со слухом, нарушение равновесия, онемение конечностей и т.д.

Лечение нарушенного кровообращения

При нарушенном кровообращении возникают следующие заболевания:

  • артериальная и венозная гиперемия
  • тромбоз
  • ишемия
  • стаз
  • эмболия
  • варикоз
  • болезнь Рейно

Для лечения нужно точно определить причину и в зависимости от нее назначать медикаментозное лечение. При острых нарушениях может потребоваться хирургическое вмешательство. Кроме того, лечение необходимо сочетать с правильным питанием (употреблять еду с низким содержанием жира и соли), отказаться от вредных привычек (курение и алкоголь) и проходить специальные процедуры для улучшения кровотока (вибротерапия, электромагнитная терапия и т.д.).

Препараты для улучшения кровообращения

Для улучшения кровообращения используются следующие группы препаратов:

1) Препараты, улучшающие микроциркуляцию – данная группа препаратов действует на сосуды микроциркулярного русла. В результате сосуды расширяются, а кровь становится менее вязкой. Как правило, препараты данной группы используют при нарушении кровообращения на фоне различных болезней (сахарный диабет, атеросклероз):

2) Препараты простагландина E1 – лекарства данной группы оказывают положительное действие на микроциркуляцию и кровоток, а также обладают гипотензивным эффектом:
вазапростан

3) Блокаторы кальциевых каналов, в основном, применяются для улучшения кровообращения головного мозга. Способствуют улучшению микроциркуляции сосудов и ограничивают повреждение мозговой ткани. К ним относятся:

  • циннаризин
  • логимакс
  • нафадил
  • нимотоп
  • циннасан
  • брейнал
  • норвакс
  • арифон
  • кордипин
  • форидон
  • нифекард
  • кордафен

4) Препараты низкомолекулярного декстрана – лекарства данной группы положительно влияют на текучесть крови, за счет привлечения дополнительных объемов крови из межклеточного пространства. К ним относятся:

  • реомакродекс
  • гемостабил
  • реополиглюкин

5) Миотропные спазмолитики – данная группа лекарств расширяет сосуды и расслабляет гладкую мускулатуру. Миотропные спазмолитики показывают высокую эффективность при спазмах сосудов головного мозга:

6) Фитопрепараты – препараты, которые создаются на основе растительного сырья. Фитопрепараты показывают высокую эффективность при болезнях сосудов головного мозга, а также при облитерирующем атеросклерозе и эндартериите. К ним относятся:

7) Альфа-адреноблокаторы – препараты данной группы способствуют лучшему кровоснабжению периферических тканей. К ним относятся:

8) Ганглиоблокаторы – данные препараты улучшают кровообращение в нижних конечностях, а также обладают выраженным гипотензивным эффектом (понижают давление):

9) Биофлавоноиды – вещества растительного происхождения, которые усиливают ток крови и улучшают состояние сосудов:

10) Стимуляторы допаминовых рецепторов – данная группа лекарств оказывает действие на допаминовые рецепторы, что, в свою очередь, приводит к расширению сосудов. Улучшают кровообращение в нижних конечностях — проноран.

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