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Инструкция по применению Хилак форте
Состав и форма выпуска
Хилак форте регулирует равновесие кишечной микрофлоры и нормализует ее состав. Благодаря содержанию в составе Хилака форте продуктов обмена нормальной микрофлоры, препарат способствует восстановлению нормальной микрофлоры кишечника биологическим путем и позволяет сохранить физиологические и биологические функции слизистой оболочки кишечника.
Входящие в состав Хилака форте биосинтетическая молочная кислота и ее буферные соли восстанавливают нормальное значение кислотности в ЖКТ независимо от того, страдает ли пациент от повышенной или пониженной кислотности.
На фоне ускорения развития нормальных симбионтов кишечника под действием Хилака форте нормализуется естественный синтез витаминов группы В и К.
Содержащиеся в препарате Хилак форте короткоцепочечные летучие жирные кислоты обеспечивают восстановление поврежденной микрофлоры кишечника при инфекционных заболеваниях ЖКТ, стимулируют регенерацию эпителиальных клеток кишечной стенки, восстанавливают нарушенный водно-электролитный баланс в просвете кишки.
Имеются данные о том, что Хилак форте усиливает защитные функции организма благодаря стимуляции иммунного ответа.
При применении Хилака форте отмечается ускорение выведения сальмонелл у грудных детей после сальмонеллезного энтерита, что обусловлено стимуляцией роста ацидофильной анаэробной кишечной флоры и ее последующим антагонистическим воздействием на сальмонеллы.
Показания к применению Хилак форте
Нарушение физиологической флоры тонкого и толстого кишечника (во время и после лечения антибиотиками или сульфаниламидами, лучевой терапии);
синдром недостаточности пищеварения, диспепсия;
диарея, метеоризм, запор;
гастроэнтерит, колит, синдром старческого кишечника (хронический атрофический гастроэнтерит);
расстройства со стороны ЖКТ, вызванные сменой климата;
гипо- и анацидные состояния;
энтерогенные заболевания желчного пузыря и печени;
аллергические кожные заболевания (крапивница, эндогенно обусловленная хроническая экзема);
сальмонеллез в стадии реконвалесценции (в т.ч. детей грудного возраста).
Противопоказания к применению Хилак форте
Хилак форте Применение при беременности и детям
Хилак форте Побочные действия
Хилак форте хорошо переносится больными любого возраста.
Побочные действия до настоящего времени не наблюдались.
Возможны аллергические реакции (кожная сыпь, зуд, крапивница); запор, диарея.
Хилак форте представляет собой препарат, который помогает восстановлению нормальной микрофлоры кишечника. Она может быть нарушена вследствие естественных причин или при лечении антибиотиками, при облучении, оперативном вмешательстве на ЖКТ и других факторах. Перед приемом лекарства изучите инструкцию по применению.
Хилак форте представляет собой препарат, который помогает восстановлению нормальной микрофлоры кишечника.
Состав
Препарат выпускается в форме прозрачного раствора. Он имеет желтоватый или янтарный цвет и кисловатый карамельный запах. В составе 100 мл раствора содержатся активные метаболиты следующих бактерий:
- Escherichia coli DSM 4087 в количестве 24,9481 г;
- Enterococcus faecalis DSM 4086 в количестве 12,4741 г;
- Lactobacillus acidophilus DSM 4149 в количестве 12,4741 г;
- Lactobacillus helveticus DSM 4183 в количестве 49,896 г.
Чтобы избежать аллергии, стоит учитывать, что в составе каждого из этих субстратов содержится лактоза.
Помимо основных действующих веществ, 100 мл препарата содержит:
- натрия фосфат гептагидрат — 1,159 г;
- дикалия фосфат — 1,265 г;
- молочную кислоту — 2,5 г;
- концентрированную фосфорную кислоту — 0,352 г;
- сорбат калия — 0,1114 г;
- лимонной кислоты моногидрат — 0,0322 г;
- воду в количестве, необходимом для получения 100 мл раствора.
Форма выпуска
Препарат выпускается только в жидкой форме, но поставляется на рынок в 2 вариантах фасовки.
Капли
Капли для приема внутрь расфасованы во флаконы из темного стекла объемом 30 или 100 мл. Каждый флакон имеет пробку-капельницу и упакован в картонную коробку. Такой вариант фасовки удобен для хранения в домашней аптечке.
Саше представляет собой пакетик из ламинированной фольги с готовой разовой дозировкой. В пакетиках содержится 1,1 или 2,2 мл препарата. В картонной пачке находится 30 упаковок-саше, которые удобно брать с собой в дорогу, на работу или на дачу.
Чем хорош Хилак форте
Данное средство способствует нормализации микрофлоры кишечника и восстановлению ее функций естественным путем. За счет использования в составе активных метаболитов полезных бактерий в жидкой форме терапевтический эффект достигается быстрее, чем при приеме сухих порошков и капсул, которым необходимо 8-10 часов на растворение и поступление действующих веществ в кишечник.
Данное средство способствует нормализации микрофлоры кишечника и восстановлению ее функций естественным путем.
Кроме того, содержащиеся в препарате компоненты оказывают благоприятное воздействие на слизистую, нормализуют ее кислотность, вследствие чего происходит подавление патогенных бактерий собственными силами организма. Поэтому данное средство назначают при следующих состояниях:
- нарушениях функций толстого и тонкого кишечника, возникающих при лечении антибиотиками, после радиотерапии;
- нарушениях пищеварения, в т. ч. при диспепсии;
- дисбактериозе кишечника (поносе или запоре);
- избыточном образовании газов (метеоризме);
- вздутии, чувстве дискомфорта в подвздошной области;
- гастрите и гастроэнтерите в разных формах;
- акклиматизации, которая сопровождается расстройством ЖКТ;
- заболеваниях желчного пузыря и печени;
- проявлениях аллергии на коже (крапивница, экзема и др.)
- сальмонеллезе, в т. ч. у грудничков.
Препарат безопасен, удобен в применении и используется для широкого спектра заболеваний. После консультации со специалистом он может применяться для лечения функциональных расстройств ЖКТ у новорожденных, детей и взрослых.
Как действует
Основным компонентом препарата являются продукты обмена веществ бактерий, которые обитают в кишечной микрофлоре в естественных условиях. Попадая в толстый кишечник, метаболиты становятся питательной средой для необходимых микроорганизмов. Благодаря этому нормализация состояния слизистой происходит быстро и физиологическим путем. За счет ускоренного размножения биологических симбионтов стабилизируются функции кишечника, в т. ч. выработка витаминов K и группы B, иммунный ответ организма, улучшается перистальтика.
Соли молочной кислоты стабилизируют уровень кислотности независимо от его первоначальных значений у пациента. А за счет содержания короткоцепочечных жирных кислот происходит ускоренная регенерация эпителиальных клеток стенок кишечника, которые могут быть повреждены из-за перенесенных инфекционных заболеваний или воздействия лекарственных препаратов.
Как принимать
Дозировка и режим приема препарата зависят от назначений врача и диагностируемого заболевания.
При запорах
При поносах или запорах необходимо бороться с дисбактериозом кишечника. Для этой цели взрослым назначают по 60 капель или 2,2 мл по 3 раза в сутки. После улучшения рекомендуется снизить дозу в 2 раза. Детям рекомендуется применять по 30 капель или саше объемом 1,1 мл по 3 раза в сутки. Младенцам до года дают по 15 капель. В последнем случае лучше использовать препарат во флаконе.
При поносах или запорах необходимо бороться с дисбактериозом кишечника. Для этой цели взрослым назначают по 60 капель или 2,2 мл по 3 раза в сутки.
При геморрое
Запоры становятся частой причиной развития геморроя. Кроме того, задержки в дефекации могут спровоцировать рецидив патологии и появление болезненных анальных трещин. При геморроидальных узлах необходимо поддерживать стабильный стул нормальной консистенции, чему способствуют активные метаболиты в составе средства. Курс препарата в данном случае составляет 1 месяц, после чего требуется сделать перерыв. Повторяйте курс в течение года при необходимости.
Способ применения Хилак форте
Капли или раствор из саше принимают одним и тем же способом.
Сколько принимать
Стандартная дозировка для взрослых при дисбактериозе составляет от 40 до 60 капель, для детей — 20-30 капель. Что касается дозировки для новорожденных, то она должна назначаться лечащим врачом или составлять не больше 15 капель. После наступления улучшения дозировку можно снизить.
Сколько дней
Рекомендованная продолжительность курса при функциональных расстройствах кишечника составляет 1 неделю, после чего наступает улучшение. Для стабилизации состояния при инфекционном поражении ЖКТ рекомендуется принимать препарат в течение 1 месяца. Потом следует сделать перерыв.
Рекомендованная продолжительность курса при функциональных расстройствах кишечника составляет 1 неделю, после чего наступает улучшение. Для стабилизации состояния при инфекционном поражении ЖКТ рекомендуется принимать препарат в течение 1 месяца.
До или после еды
Препарат применяют до или во время приема пищи, запивая небольшим количеством любой жидкости, за исключением молока.
Применение при беременности и лактации
Данных о противопоказаниях при беременности или при грудном вскармливании не существует. Препарат считается безопасным как для матери, так и для плода, но окончательное решение о целесообразности приема принимается специалистом.
Как давать ребенку
Дети часто отказываются принимать препарат, поскольку он имеет кислый привкус. Но благодаря небольшой дозировке его легко замаскировать другими продуктами. Например, необходимую дозу можно добавить в суп, кашу на воде или в напитки (соки, морсы, компоты, чай). Обратите внимание, что нельзя сочетать средство с молочными продуктами любой консистенции (молоко, кефир, творог, йогурт и др.).
Описание актуально на 29.02.2016
- Латинское название: Hylak forte
- Код АТХ: A07FA
- Действующее вещество: Водные субстраты продуктов обмена веществ
- Производитель: Merckle (Германия)
Состав
В состав Хилак Форте в качестве активно действующего компонента входит субстрат продуктов метаболизма (водный, беззародышевый):
- Escherichia coli (кишечной палочки), штамм DSM 4087 (0,249481 г/мл);
- Lactobacillus acidophilus (штамм DSM 4149) и helveticus (штамм DSM 4183) (0,124741 и 0,49896 г/мл, соответственно);
- Enterococcus faecalis (фекальных энтерококков), штамм DSM 4086 (0,124741 г/мл).
В качестве вспомогательных компонентов в состав препарата входят: фосфат гептагидрат натрия, фосфат калия, фосфорная (концентрированная) и молочная кислоты, лимонная кислота в форме моногидрата, калия сорбат.
Лактоза в состав капель входит как продукт жизнедеятельности микроорганизмов.
Форма выпуска
Оральные капли Хилак Форте представляют собой прозрачную жидкость со специфическим кисловатым запахом. Цвет раствора может варьироваться от желтоватого до желтовато-коричневого. Раствор выпускается в флаконах с пробкой-капельницах по 30 и 100 мл.
Фармакологическое действие
Согласно аннотации, препарат способствует нормализации кишечной микрофлоры.
Фармакодинамика и фармакокинетика
Действие препарата направлено на восстановление нарушенного баланса нормофлоры кишечника, нормализацию рН в просвете кишечника, баланса воды и электролитов, стимуляцию синтеза клеток эпителия кишечной стенки.
Нарушению естественной кишечной микрофлоры и чрезмерному размножению патогенной микрофлоры способствуют такие внешние воздействия, как прием антибиотиков, хирургическая операция на желудке (операция Бильрот II), облучение, нарушения питания. Как результат возникают запор/диарея и ощущение тяжести.
Введенные в состав препарата многочисленные продукты метаболизма физиологических кишечных микроорганизмов (Грам (+) и Грам (-) симбионтов тонкого и толстого кишечника, а также микробов, продуцирующих молочную кислоту, способствуют сохранению нормальной функции слизистой кишечника и восстановлению его естественной микрофлоры.
Содержащиеся в каплях биосинтетическая молочная кислота и ее буферные соли способствуют нормализации pH среды кишечника, а летучие кислоты жирного ряда делают возможным не только профилактику повреждений кишечной среды, но и восстанавливают ее в случае повреждения при инфекционных заболеваниях желудка и кишечника, а также способствуют всасыванию электролитов и воды (хлор, натрий).
Через кровь Хилак Форте не всасывается. Выводится препарат через ЖКТ.
Показания к применению: от чего помогают капли Хилак Форте?
Показания к применению Хилак Форте:
- расстройства пищеварения (препарат эффективен при запорах, диарее, метеоризме);
- прием сульфаниламидных препаратов и антибиотиков, радиотерапия (капли целесообразно принимать как во время терапии, так и по ее завершении);
- метаболические заболевания печени;
- гастроинтестинальные расстройства, которые обусловлены пониженной кислотностью;
- сенильный кишечник (хронический атрофический гастроэнтерит);
- обусловленные изменением климата расстройства желудка и кишечника;
- симптомы, ассоциированные с хронической кишечной интоксикацией(нарушение кровообращения, тошнота, склонность к быстрой усталости и т.д.);
- кожные аллергические заболевания;
- сальмонеллез(в период выздоровления, в том числе у грудных детей);
- энтерогенные заболевания желчного пузыря.
Хилак Форте является средством поддерживающей терапии. Препарат должен применяться только в сочетании с другими эффективными лечебными мероприятиями.
Так, например, при диарее капли не могут заменить терапию, направленную на восполнение потери жидкости, диету, подразумевающую отказ от употребления твердой пищи и прочие меры.
Противопоказания
Прием капель противопоказан при:
- повышенной чувствительности к их компонентам;
- острых проявлениях диареи, сопровождающейся наличием крови в кале и гипертермией.
Побочные действия
Побочные действия препарата проявляются очень редко. Как правило, это реакции слизистой оболочки и кожные проявления аллергии, обусловленные гиперчувствительностью к компонентам капель.
Кроме того, фиксировались отдельные жалобы на ощущение дискомфорта в брюшной полости.
Капли Хилак Форте, инструкция по применению
В инструкции по применению Хилак Форте указывается, что капли следует принимать внутрь, с едой или непосредственно перед приемом пищи. Перед тем, как выпить лекарство, его растворяют в небольшом количестве жидкости (но не в молоке).
Как принимать взрослым Хилак Форте?
Рекомендации, как пить взрослым препарат, следующие: капли принимают в дозе, составляющей от 40-60 капель на прием до 3 раз в течение дня. В первые дни болезни кратность применений — 3 р./день, в дальнейшем количество приемов сокращают.
Длительность курса лечения взрослым подбирается индивидуально.
При наличии хеликобактер пилори в желудке лечение Хилак-бактериями назначают как дополнение к курсу лечения препаратами типа Галстены и в сочетании, например, со Смектой.
Хилак Форте для новорожденных и для детей старшего возраста
Препарат не предназначен для грудничков. В педиатрии применяется с двухлетнего возраста. Разовая доза для ребенка 2-12 лет — от 20 до 40, для ребенка старше 12 лет — от 40 до 60 капель.
Передозировка
У взрослых случаи передозировки не фиксировались.
При случайном проглатывании ребенком препарата возможно рефлекторное срыгивание, которое может стать причиной развития аспирационной пневмонии. В ряде случаев это требует госпитализации пострадавшего. Терапия симптоматическая.
Взаимодействие
Антацидные средства могут нейтрализовать входящую в состав капель молочную кислоту.
Условия продажи
Условия хранения
Хранить в светозащищенном месте при температуре ниже 25°C.
Срок годности
Четыре года. После вскрытия флакона раствор считается годным к применению в течение шести недель.
Особые указания
Не следует принимать Хилак Форте в неразбавленном виде и разведенным молоком. Препарат должен с осторожностью назначаться пациентам с повышенной кислотообразующей функцией желудка.
Аналоги Хилак форте
Аналогами препарата являются: Ацилакт, Аципол, Биоспорин, Бифиформ, Линекс, Бифидумбактерин, Споробактерин, Бификол, Флонивин БС, Энтерол, Бифинорм, Лактобактерин, Нормофлорин.
Цена аналогов — от 168 руб. Наиболее дешевые аналоги Хилак Форте — это препараты Наринэ, Нормофлорин, Лактобактерин.
Чем отличаются Хилак и Хилак Форте?
Отличием препаратов Хилак и Хилак Форте является их состав. В Хилак Форте содержатся продукты обмена веществ кишечной палочки, фекальных энтерококков и лактобацилл. В каплях Хилак содержатся только водный концентрат продуктов метаболизма лактобацилл L. helveticus, штамм DSM 4183.
Хилак Форте или Линекс — что лучше?
Линекс — это комбинированное лекарственное средство, в котором в качестве действующей субстанции содержится лиофилизат трех видов жизнеспособных молочнокислых бактерий, являющихся частью нормальной флоры кишечного тракта.
Терапевтическое и профилактическое действие микроорганизмов обеспечивается за счет:
- сдвига рН в кислую среду, в которой подавляется рост условно-патогенных и патогенных бактерий, а также поддерживается оптимальное действие пищеварительных ферментов;
- синтеза бактериями витаминовВ1, В2, В6,В12 и К;
- участия бактерий в метаболизме желчных пигментов и желчных кислот;
- предотвращения молочнокислыми бактериями адгезии представителей патогенной кишечной флоры к стенкам кишечника;
- синтеза микроорганизмамибактериоцинов (веществ с антибактериальной активностью);
- стимуляции местного иммунитета в кишечнике и гуморального иммунитета.
Препарат назначают при дисбактериозе, который проявляется срыгиваниями, диспепсией, диареей/запором, метеоризмом, вздутием живота, тошнотой, болью в животе, рвотой.
Лактофильтрум или Хилак Форте — что лучше?
Лактофильтрум — это сорбент растительного происхождения с иммуномодулирующими свойствами. Применение препарата показано при состояниях, которые сопровождаются нарушением баланса микрофлоры кишечника, а также когда необходима дезинтоксикация организма (например, при отравлении продуктами метаболизма, лекарствами или токсинами).
Активными веществами Лактофильтрума являются природный энтеросорбент лигнин и синтетический пребиотик лактулоза.
Если единственным противопоказанием к применению Хилак Форте является непереносимость его компонентов, Лактофильтрум не назначают при:
- желудочно-кишечных кровотечениях;
- непроходимости кишечника;
- галактоземии.
Относительными противопоказаниями к его применению являются язва желудка или 12-типерстной кишки (в стадии обострения) и атония кишечника. Хилак Форте безопасен для беременных и кормящих женщин, тогда как безопасность Лактофильтрума для указанных категорий пациентов не доказана.
Что лучше: Хилак Форте или Аципол?
Аципол — это препарат на основе кефирных грибков (инактивированных прогреванием) и ацидофильных лактобактерий (живых, антагонистически активных).
По механизму действия препарат представляет собой многофакторное средство: Аципол проявляет антагонистическую активность в отношении условно-патогенных и патогенных бактерий, восстанавливает баланс микрофлоры кишечника, способствует повышению иммунологической реактивности организма.
Препарат не имеет других противопоказаний кроме непереносимости его компонентов. Побочные эффекты в период его применения не фиксировались. В педиатрии Аципол может применяться с трехмесячного возраста.
Что лучше: Бифиформ или Хилак Форте?
Основой Бифиформа являются бифидобактерии и энтерококки, основой препарата Хилак Форте — лактобактерии двух видов, кишечные палочки и фекальные энтерококки.
Разные виды микроорганизмов, несмотря на то, что являются компонентам естественной микрофлоры кишечника, обладают несколько отличными свойствами.
Оба препарата предназначены для лечение дисбактериоза, поддержания необходимого уровня кислотности, восстановления нормофлоры, однако в состав Бифиформа входят не только анаэробы, но и аэробные бактерии, которые надежно защищены кислоторастворимой оболочкой. Благодаря этому препарат может действовать в том числе в толстом кишечнике. То есть Хилак Форте “работает” только на двух участках пищеварительного канала, а Бифиформ — сразу на трех.
Отличием средств является также и то, что Хилак Форте имеет только одну форму выпуска — капли, а препарат Бифиформ выпускается производителем в виде капель, порошка, капсул, жевательных таблеток, в которые включены различные биологически активные добавки. Последние расширяют выбор потребителя и позволяют решать дополнительные проблемы с ЖКТ.
Хилак Форте для детей
Как детям принимать капли Хилак Форте?
Разовая доза препарата для ребенка моложе 12 лет — от 20 до 40 капель. В острой стадии болезни лекарство следует принимать трижды в день. В дальнейшем кратность применений снижают. Суточная доза по мере улучшения также может быть снижена вдвое.
При изжоге и повышенной кислотности желудочного сока суточную дозу необходимо делить как минимум на три приема.
Инструкция для детей старше 12-ти лет аналогична инструкции для взрослых: разовая доза для указанной группы пациентов варьируется от 40 до 60 капель. В первые дни лечения кратность применений — 3 р./день.
По мере улучшения состояния больного лечение продолжают в половинной дозе.
Отзывы о Хилак Форте для детей в основной массе положительные: по наблюдениям мам препарат действительно хорошо помогает при болях и дискомфорте в животе. Недостатками средства обычно называют только его специфический вкус и короткий срок хранения после вскрытия флакона.
Сколько времени принимать лекарство детям?
Точно сказать, сколько дней принимать препарат, нельзя, поскольку длительность курса врач определяет индивидуально в зависимости от особенностей клинической ситуации и ответа на лечение.
Хилак Форте для новорожденных
В инструкции указывается, что препарат не предназначен для лечения детей до двух лет.
Однако в некоторых случаях Хилак Форте для грудничков все же назначают. Обычно педиатры прописывают их для младенцев, получающих лечение антибиотиками, а также в ситуациях, когда у ребенка отмечаются:
- нестабильный стул;
- вздутие живота;
- частые срыгивания;
- ослабленная работа кишечника;
- запоры, понос и любые другие расстройства кишечника.
Разовая доза для младенца — от 15 до 30 капель. Кратность применений — 3 р./день. По мере улучшения состояния ребенка дозу и количество приемов сокращают.
Как давать грудничку капли Хилак Форте?
Для грудничков лекарство необходимо разводить небольшим количеством теплой воды (не молока!), в которую добавлена глюкоза. Кормление ребенка можно начинать через час после применения капель.
Отзывы для новорожденных свидетельствуют о том, что препарат весьма эффективен при сбоях работы желудка и кишечника у детей: у грудничков, принимавших Хилак Форте, довольно быстро начинает развиваться полезная микрофлора, восстанавливаются кислотность, слизистая стенок кишечного тракта и водно-электролитный баланс.
Хилак Форте при беременности
При беременности и лактации применение препарата считается безопасным. Решение о назначении капель может принимать только врач.
Отзывы о Хилак Форте
Отзывы врачей и пациентов о препарате Хилак Форте в подавляющем большинстве положительные. Препарат хорошо помогает от запоров, метеоризма, диареи и, кроме того, он эффективен от прыщей и кожных проявлений аллергии.
Больше всего на форумах встречается отзывов о Хилак Форте для детей и, в частности, для грудничков, у которых расстройства ЖКТ возникают особенно часто. Почти все родители уверяют, что средство очень удобно в применении и эффективно при большинстве возникающих у маленьких детей проблем.
В отзывах о Хилак Форте для новорожденных мамы иногда отмечают, что для них недостатком препарата стало то, что капли нельзя разводить в молоке. Мамы детей постарше иногда минусом лекарства называют его специфический кислый вкус.
Сколько стоит Хилак Форте?
На капли Хилак Форте цена в российских аптеках варьируется от 246 до 1455 руб. Стоимость этого средства для детей и взрослых зависит от объема флакона и количества флаконов в упаковке.
Так цена Хилак форте 30 мл — 246-285 руб, цена флакона 100 мл — 460-560 руб, а стоимость упаковки из 3-х флаконов по 100 мл — 1145-1453 руб.
Цена Хилак Форте в Украине — от 72 грн: флакон 30 мл с каплями для новорожденных можно приобрести за 72-90 грн, флакон 100 мл в Харькове, Киеве или, например, Одессе стоит, в среднем, 195 грн.
Купить в Минске препарат можно от 51 тыс. руб за флакон 30 мл и от 123,5 тыс. руб. за флакон 100 мл.
Производитель не выпускает таблетки Хилак Форте. Единственная лекарственная форма препарата — капли.
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