Гепарин-Акрихин 1000: инструкция по применению и отзывы
Латинское название: Heparin-Akrihin 1000
Код ATX: C05BA03
Действующее вещество: гепарин натрия (Heparin sodium)
Производитель: Химико-фармацевтический комбинат АКРИХИН, АО (Россия)
Актуализация описания и фото: 10.07.2019
Цены в аптеках: от 208 руб.
Гепарин-Акрихин 1000 – антикоагулянтное средство прямого действия для местного применения.
Форма выпуска и состав
Лекарственная форма – гель для наружного применения: почти прозрачный или прозрачный, бесцветный или со слегка желтоватым оттенком, со специфическим запахом (в алюминиевых тубах по 20, 30, 40 и 50 г, в картонной пачке 1 туба и инструкция по применению Гепарина-Акрихин 1000).
Состав 1 г геля:
- активное вещество: гепарин натрия (в пересчете на сухое вещество) – 8,3 мг (1000 Международных единиц);
- вспомогательные компоненты: вода очищенная, карбомер 940, метилпарагидроксибензоат, этанол 96% (спирт этиловый ректификованный), трометамол, апельсина цветков масло (неролиевое масло), лаванды масло.
Фармакологические свойства
Фармакодинамика
Гепарин натрия оказывает противоотечное и умеренное противовоспалительное действие.
При наружном применении препятствует образованию тромбов.
Фармакокинетика
Информация не предоставлена производителем.
Показания к применению
- ушибы мягких тканей и суставов;
- локализованные инфильтраты и отеки мягких тканей;
- тромбофлебит поверхностных вен;
- травмы сухожилий и суставов.
Противопоказания
- язвенно-некротические изменения кожи в местах предполагаемого нанесения препарата;
- травматическое нарушение целостности кожных покровов;
- тромбоцитопения;
- пониженная свертываемость крови;
- известная гиперчувствительность к любому компоненту препарата.
Гепарин-Акрихин 1000, инструкция по применению: способ и дозировка
Гель Гепарин-Акрихин 1000 предназначен для наружного применения. Препарат следует наносить на область поражения и осторожно втирать в кожу. Необходимую дозу определяют таким образом, чтобы на участок кожи 3–5 см в диаметре приходилось 3–5 см геля.
Кратность аппликаций – от 1 до 3 раз в сутки.
Лечение нужно продолжать до исчезновения воспалительных явлений, средняя длительность терапии – 3–7 дней.
Побочные действия
На фоне применения препарата возможно появление гиперемии кожи в месте нанесения геля, развитие кожных аллергических реакций.
Передозировка
Компоненты препарата характеризуются низкой всасываемостью, поэтому передозировка маловероятна.
Особые указания
Гель Гепарин-Акрихин 1000 не рекомендуется применять при глубоком венозном тромбозе, кровотечениях и местных гнойных процессах, а также на открытых ранах и слизистых оболочках.
С особой осторожностью нужно использовать при повышенной проницаемости сосудов.
Влияние на способность к управлению автотранспортом и сложными механизмами
Отрицательного влияния на скорость реакций и способность к концентрации внимания препарат не оказывает.
Лекарственное взаимодействие
Гепарин-Акрихин 1000 не рекомендуется смешивать с другими препаратами для наружного применения.
Противопоказано применять средство с тетрациклинами, нестероидными противовоспалительными и антигистаминными препаратами.
Аналоги
Сроки и условия хранения
Хранить в недоступном для детей месте при температуре 15–25 °С.
Срок годности – 2 года.
Условия отпуска из аптек
Отпускается без рецепта.
Отзывы о Гепарине-Акрихин 1000
Отзывы о Гепарине-Акрихин 1000 положительные. Многие называют его «домашним доктором» от ушибов, синяков и отеков, венозной сеточки. К дополнительным преимуществам относят быструю впитываемость геля и доступную стоимость. Сообщений о развитии нежелательных реакций во время терапии нет.
Цена на Гепарин-Акрихин 1000 в аптеках
В зависимости от региона продажи и аптечной сети цена на Гепарин-Акрихин 1000 составляет примерно 226–340 руб. за тубу объемом 30 г, 299–420 руб. за тубу объемом 50 г.
Гепарин-Акрихин 1000: цены в интернет-аптеках
ГЕПАРИН-АКРИХИН 1000 30г гель для наружного применения
Гепарин-Акрихин 1000 1000 МЕ/г гель для наружного применения 30 г 1 шт.
Гепарин-акрихин 1000 гель 30 г
Гепарин-Акрихин 1000 1000 МЕ/г гель для наружного применения 50 г 1 шт.
ГЕПАРИН-АКРИХИН 1000 1000МЕ/г 50г гель для наружного применения
Гепарин-Акрихин 1000 МЕ гель 30г
Гепарин-Акрихин 1000 МЕ гель 50г
Образование: Первый Московский государственный медицинский университет имени И.М. Сеченова, специальность "Лечебное дело".
Информация о препарате является обобщенной, предоставляется в ознакомительных целях и не заменяет официальную инструкцию. Самолечение опасно для здоровья!
В течение жизни среднестатистический человек вырабатывает ни много ни мало два больших бассейна слюны.
При регулярном посещении солярия шанс заболеть раком кожи увеличивается на 60%.
Препарат от кашля «Терпинкод» является одним из лидеров продаж, совсем не из-за своих лечебных свойств.
Для того чтобы сказать даже самые короткие и простые слова, мы задействуем 72 мышцы.
В четырех дольках темного шоколада содержится порядка двухсот калорий. Так что если не хотите поправиться, лучше не есть больше двух долек в сутки.
Многие наркотики изначально продвигались на рынке, как лекарства. Героин, например, изначально был выведен на рынок как лекарство от детского кашля. А кокаин рекомендовался врачами в качестве анестезии и как средство повышающее выносливость.
Люди, которые привыкли регулярно завтракать, гораздо реже страдают ожирением.
Большинство женщин способно получать больше удовольствия от созерцания своего красивого тела в зеркале, чем от секса. Так что, женщины, стремитесь к стройности.
Наши почки способны очистить за одну минуту три литра крови.
В нашем кишечнике рождаются, живут и умирают миллионы бактерий. Их можно увидеть только при сильном увеличении, но, если бы они собрались вместе, то поместились бы в обычной кофейной чашке.
Если улыбаться всего два раза в день – можно понизить кровяное давление и снизить риск возникновения инфарктов и инсультов.
Существуют очень любопытные медицинские синдромы, например, навязчивое заглатывание предметов. В желудке одной пациентки, страдающей от этой мании, было обнаружено 2500 инородных предметов.
Печень – это самый тяжелый орган в нашем теле. Ее средний вес составляет 1,5 кг.
Если бы ваша печень перестала работать, смерть наступила бы в течение суток.
Во время чихания наш организм полностью прекращает работать. Даже сердце останавливается.
Если вам срочно нужна помощь стоматолога, или вы занимаетесь подбором постоянного специалиста для себя и семьи, пройдите по ссылке, и вы обязательно найдете под.
Для лечения геморроя используют множество лекарственных средств. Среди широкого ассортимента, который представлен на фармацевтическом рынке, можно выделить препараты на основе гепарина, поскольку они эффективны, имеют привлекательную цену и безопасны. Одним из таких препаратов является Гепарин-Акрихин, который эффективен при геморрое.
Состав и действие препарата
100 г мази содержат следующие вещества: основное — гепарин натрия — в количестве 0,83 г (эквивалентно 100000 МЕ); другие компоненты — метилпарагидроксибензоат в дозе 0,15 г, трометамол — 0,85 г.
Форма выпуска
Гель для использования на неповрежденной коже и слизистых.
Фармакологическое действие
Гепарин — антикоагулянт прямого действия, является естественным для организма веществом, которое способно замедлить свертывание крови, в том числе препятствует тромбообразованию. Метилпарагидроксибензоат имеет свойство подавлять рост дрожжей и грибов, трометамол -противоотечный компонент, уменьшение отеков достигается усиленным мочеиспусканием.
Фармакодинамика и фармакокинетика
По строению гепарин является гликозаминогликаном. Его молекула имеет особые свойства, улучшающие взаимосвязь с белками и свертываемость крови.
Гепарин контактирует с антитромбином III (является кофактором гепарина) и подавляет процесс тромбообразования путем деактивации V, VII, IХ, X факторов свертываемости. При этом разрушается цепочка факторов, ответственных за образование сгустка, нарушается превращение протромбина в тромбин.
Большие дозы гепарина могут угнетать процесс коагуляции через преобразование тромбина в неактивную форму (белок крови необходим для образования тромбового сгустка), что в свою очередь препятствует синтезу конечного продукта коагуляции — фибрина.
При местном использовании гепарин не влияет на функционирование органов и систем организма и не накапливается в них, хотя в общий кровоток незначительное количество действующих компонентов препарата попадает.
После всасывания в кровь вещества проходят биотрансформацию (частичное обезвреживание) в печени (это происходит в ретикулоэндотелиальной системе). Связывание с белками плазмы составляет 95%. Период полувыведения организмом колеблется от 60 до 90 минут. Выведение осуществляется почками, что нужно учитывать пациентам с наличием заболеваний почек с высокими показателями креатинина.
Для чего применяют Гепарин Акрихин
Для местного использования данный препарат применяется в терапии воспаления подкожных вен нижних конечностей, мигрирующих флебитов, а также при варикозе и его осложнениях в виде язв варикозно расширенных вен; при ухудшении состояния сосудов после проведения операций по поводу заболеваний вен; для лечения небактериальных уплотнений, локальных отеков, травм сухожилий и суставов, различных заболеваний суставов.
Гепарин применяют в комплексной терапии тромбоза геморроидальных вен и профилактики данного состояния и в терапии острых воспалительных патологий вен.
Применение при геморрое
При хронической форме
При хроническом геморрое, тромбозе геморроидальных вен способ применения мази гепарина такой: мазь наносят либо на узлы и прикрывают повязкой, если у пациента есть выпадающие узлы наружного геморроя. Пропитывают ватно-марлевый тампон мазью, после чего тампон нужно поместить в прямую кишку на глубину расположения узлов.
Курс терапии составляет от 1 до 3 недель, но может быть продлен с учетом степени тяжести болезни.
При обострении
В случае появления трофических язв на гемороидальных узлах Гепариновую мазь следует наносить только на околоязвенные участки. При недостаточном эффекте от местного нанесения мази следует парентерально вводить раствор гепарина для достаточного терапевтического эффекта.
Противопоказания
Если у пациента имеются язвенные дефекты в местах, пораженных тромбофлебитом, включая геморроидальные узлы, то данную мазь не применяют.
При наличии заболеваний печени препарат используется только по показаниям (особенно при циррозе печени).
При сниженной свертываемости крови гепарин может вызвать внутренние кровотечения, поэтому в таких случаях средство на его основе не применяют.
При повышенной чувствительности к гепарину или другим составляющим использование данного препарата противопоказано.
Применять при кровотечениях гепарин небезопасно. При кровоточащем геморрое лекарственный препарат нужно отменить.
Побочные действия препарата Гепарин Акрихин
Побочные действия представлены кожными аллергическими реакциями в виде высыпаний. В редких случаях возможно возникновение ангионевротического отека.
При индивидуальной непереносимости и появлении аллергических реакций при первом применении препарат отменяют и назначают противоаллергические средства.
Передозировка
Если гель был нанесен на обширные участки кожи, возможно появление системные осложнения, в основе которых лежат кровоизлияния (появление множественных кровоизлияний на коже, повышенный риск возникновения внутренних кровотечений). При возникновения таких ситуаций использование мази прекращают и вводят специфический антидот — протамина сульфат.
Применение и дозировка лекарства Гепарин Акрихин
На необходимый участок кожи мазь наносят легкими движениями. Достаточно 3 см мази применять до 3 раз в сутки.
При тромбофлебите на воспаленные участки и прилегающие места гель наносят так, чтобы образовался слой толщиной 1 мм. Если есть трофическая язва, то саму язву не трогают, наносят только на окружающие ее ткани.
Дозировка и продолжительность терапии определяются лечащим врачом. При регулярном использовании геля позитивные результаты становятся явными через 2 недели.
Взаимодействие
Гепариновая мазь может вызвать удлинение протромбинового времени у тех больных, которые принимают любые другие антикоагулянты. При их одновременном приеме необходимо регулярно проводить коагулограмму. Совместно эти средства необходимо использовать с особой осторожностью.
Эффект действующих веществ мази увеличивается при совместном использовании с НПВС, а также при употреблении венотоников.
Особые указания
В течение курса использования мази необходимо контролировать показатели свертываемости крови.
Нельзя использовать гель на участках с поврежденной кожей и при трофических язвах, чтобы избежать массированного попадания действующих веществ в системный кровоток.
Применение в детском возрасте
Детям противовоспалительное лекарство наносят тонким слоем. Однократная доза зависит от размера поврежденного участка кожи, длина полоски мази может составлять 0,5-3 см. Препарат используют от 1 до 3 раз в день, а длительность лечения обуславливается скоростью улучшения состояния ребенка.
При беременности и лактации
Из-за наличия вспомогательных компонентов в этом наружном средстве Гепарин не рекомендуется использовать в первом триместре беременности. Во втором и третьем триместрах возможно его применение, но только под контролем и по назначению врача.
На время лактации следует прекратить лечение, поскольку компоненты лекарства будут накапливаться в материнском молоке и передаваться ребенку.
Аналоги
На фармацевтическом рынке сегодня представлены некоторые аналоги: Тромбогель 1000, Лавенум, Тромблесс, Лиотон 1000. Данные препараты не отличаются по эффективности.
Условия продажи
Данное средство продается в аптеках без рецепта. 1 туба содержит 25 г геля.
Средняя стоимость на фармацевтическом рынке составляет 250 рублей за упаковку.
Условия хранения и срок годности
Мазь нужно хранить в сухом, скрытом от прямого пропадания солнечных лучей месте. Беречь от детей.
При соблюдения температурного режима срок годности составляет 3 года от даты изготовления, указанной на упаковке.
Отзывы врачей и пациентов
Дмитрий, 43 года: "Использую данную мазь для лечения хронического геморроя. Раньше не лечил ничем, все время была боль, когда ходил в туалет. После двух недель использования чувствую себя намного лучше".
Алексей, врач-проктолог: "Назначаю данный препарат пациентам на протяжении своей 15-летней врачебной практики. Осложнений, кроме индивидуальной непереносимости, не встречал. Незаменимый препарат в терапии хронического геморроя, пациенты выздоравливают намного быстрее, сроки лечения гораздо меньше, чем при применении стандартной схемы терапии".
Владимир, 52 года: "Страдаю геморроем уже 10 лет, иногда выпадают узлы. Врач назначил мазь с гепарином. Облегчение настало где-то через месяц, регулярно смазываю узлы. Жалко что не обращался к врачу раньше".
Антикоагулянт прямого действия для местного использования. Применение: тромбофленбит, геморрой, варикоз. Цена от 243 руб.
Аналоги: Лавенум, Тромбогель, Гепатромбин С.
Что за препарат
Гепарин акрихин 1000 – это гель для наружного применения. Относится к антикоагулянтам прямого действия. Применяют при симптомах варикоза, тромбофлебита.
Данный препарат используют при разных травмах, ушибах, тромбофлебите и признаках варикоза. Имеет прозрачный или полупрозрачный цвет, специфический запах. Предназначен исключительно для местного применения.
Действующее вещество и состав
Активным веществом является гепарин натрия. Также в состав входят дополнительные компоненты: карбомер, трометамол, этанол, масло лаванды и цветков апельсин, очищенная вода, метилпаргид-роксибензонат. Перед использованием следует изучить состав, чтобы исключить наличие лекарственной аллергии.
Фармакологические свойства
Гепарин является антикоагулянтом прямого действия. Оказывает умеренное противовоспалительное, противоотечное действие. Предотвращает образование тромбов.
Эффективность наблюдается практически сразу после нанесения на кожу. Снижается выраженность оттеков, нормализируется цвет кожи.
Фармакодинамика и фармакокинетика
Лекарство снижает развитие тромбов. Имеет свойство снижать активность тромбина и гилуронидазы. Способствует нормализации микроциркуляции крови, регенерации тканей. После использования ускоряется процесс рассасывания гематом, тромбов.
Наблюдается незначительная абсорбция активного компонента на поверхности кожи и в системном кровотоке. После нанесения максимальная концентрация возникает через 8 часов. Выводится в основном через почки.
Показания к применению
Гепарин акрихин 1000 гель инструкция по применению содержит информацию, в каких случаях назначают препарат. К ним относятся:
Важно учитывать, что лекарство можно использовать только наружно, в местах ушибов и воспаления. Иногда применяют от синяков, для быстрого рассасывания и регенерации мягких тканей.
Противопоказания к применению
Гепарин акрихин гель противопоказан при наличии таких факторов:
- язвы и открытые раны на коже;
- нарушение целостности кожного покрова, в связи с травмой;
- снижение свертываемости крови;
- тромбоцитопения;
- гиперчувствительность к компонентам в составе.
При наличии противопоказаний категорически запрещено пользоваться данным гелем. Если у пациента есть лекарственная аллергия, следует об этом сообщить лечащему врачу.
Способ применения и дозировка
Гепариновый гель наносят на место поражением тонким слоем примерно 3-5 см. Потом легкими движениями втирают в кожу. Можно использовать несколько раз в сутки до тех пор, пока не исчезнут симптомы воспаления.
Курс лечения в основном длится 5-7 дней. При необходимости врач может повышать дозировку и продлевать терапию.
Гепарин акрихин 1000 при геморрое принимают только в том случае если, отсутствует кровотечение, строго по назначению врача. Обычно применяют на начальной стадии развития.
В детском возрасте, при беременности и ГВ
Нет противопоказаний для применения в период беременности и лактации. Но лечение возможно только под строгим контролем врача.
Дозировка должна быть минимальной, чтобы не возник вред для здоровья.
Побочные эффекты
В большинстве случаев препарат переносится очень хорошо. Данный гель редко вызывает нежелательные реакции. К ним относятся:
- снижение аппетита;
- тошнота;
- нарушение пищеварения;
- покраснение кожи;
- сыпь;
- зуд;
- ощущение жара;
- бронхоспазмы.
При развитии побочных эффектов следует отказаться от приема лекарства и обратиться к врачу.
Особые указания
С осторожностью назначают пациентам, которые страдают от повышенной проницаемости сосудов. Не рекомендуют принимать при выраженном и тяжелом тромбозе.
Препарат не влияет на концентрацию внимания, возможность водить транспортными средствами. Не влияет на снижение умственной деятельности.
Передозировка
Случаи передозировки в клинической практике встречаются очень редко. Первым признаком является кровотечение. Обычно это возникает по вине самого пациента, который намеренно превышает дозировку для достижения быстрого лекарственного эффекта.
Если человек случайно повторно нанес гель на кожу – линимент следует устранить с помощью салфетки и пропустить один прием.
Лекарственное взаимодействие
Противосвертывающее действие препарата может усиливаться, если одновременно принимать с другими антикоагулянтами, антиагрегантами и нестероидными противовоспалительными средствами.
Основное действие лекарства снижается при взаимодействии с такими веществами: алкалоиды, тироксин, тетрациклин, никотин. Поэтому следует перед применением тщательно изучить инструкцию.
Аналоги
Известные заменители лекарства:
Выбирать заменитель должен только лечащий врач. Не рекомендуется самостоятельно принимать любые лекарственные препараты.
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