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Цитофлавин (Cytoflavin): 9 отзывов врачей, 5 отзывов пациентов, инструкция по применению, аналоги, инфографика, 2 формы выпуска, цены от 112 до 1450 руб.
Цены на цитофлавин в аптеках Москвы
| раствор для внутривенного введения | 10 мл | 10 шт. | ≈ 1098,7 руб. |
| 10 мл | 5 шт. | ≈ 605 руб. | |
| таблетки, покрытые кишечнорастворимой оболочкой | 100 шт. | ≈ 789 руб. | |
| 50 шт. | ≈ 455 руб. |
Отзывы врачей о цитофлавине
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Спорное впечатление, с одной стороны хорош при астенических состояниях, в том числе при церебрастении, с другой стороны ужасен на вкус, раздражает слизистые вплоть до кишечника, обостряет обменные солевые процессы при подагре, уролитиазе.
Даже на парентеральное введение побочные со стороны желудочно-кишечного тракта.
Необходимо подбирать дозу, но если все сошлось, то работает при ВСД , интоксикациях, астеническом синдроме.
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Несколько раз помогал при снятии астенической симптоматики при неврозе.
Опыт применения "Цитофлавина" у меня в целом сложился негативный. Моё субъективное мнение — не применять препарат при сосудистых заболеваниях, так как почти всегда проявляются какие-либо побочные эффекты, а помощи в лечении не заметно.
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Часто использую в парентеральной форме при интоксикациях различного генеза. Эффект наступает уже в процессе введения препарата. Может заменять введение реамберина (при его отсутствии), т.к. имеет сходный состав.
У чувствительных пациентов возникает першение во рту. При этом необходимо уменьшать скорость введения препарата.
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Препарат прекрасно работает в парентеральной форме введения у пациентов в послеоперационном периоде, так как позволяет быстро восстановиться после наркоза, хорошо работает при алкогольных интоксикациях, да и в принципе в токсикологии, замечательно сочетаясь с препаратами калия и рибоксином.
При быстром внутривенном введении вызывает першение в горле, чувство жара, затруднение дыхания, но при медленном введении побочные эффекты янтарной кислоты нивелируются.
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Великолепный препарат против астенического синдрома, в том числе при ОРВИ и психических расстройствах.
Стоимость неоправданно высока, дискомфорт при введении, не очень хорошо переносится астматиками.
Копеечные компоненты в общем растворе превращаются в весьма недешевое средство с низким комплаенсом. Но эффективность берёт своё, пользуемся.
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Доступность, эффективность, цена.
Пока нечего сказать.
Часто использую данный препарат в своей практике, как при профилактике сосудистых заболеваний у пожилых людей, так и при лечении. Хорошо себя показал у больных, перенесших ОНМК в комплексной терапии, считаю незаменимым в реабилитационный период. При приёме препарата хотелось бы отметить, что лучше принимать во время или после еды, а не как указано в инструкции "до", т.к. янтарная кислота всё-таки оказывает влияние на слизистую желудка, на что иногда жалуются мои пациенты.
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"Цитофлавин" при парентеральном использовании эффективнее назначать в разведении с 5% раствором глюкозы (при отсутствии у пациента диабета). Хорошо переносится возрастной группой пациентов при соблюдении особых указаний препарата. В качестве метаболического средства подходит для применения в комплексном лечении цереброваскулярных заболеваний.
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Один из основных препаратов, применяемых при вегетативной нестабильности различной этиологии, при нарушениях мозгового кровообращения. Может применяться как монопрепарат, так и в комбинации.
Достаточно часто побочные эффекты, проявляющиеся в первую очередь в виде диспепсических явлений. Назначение препарата после еды несколько нивелирует этот побочный эффект. На голодный желудок принимать с осторожностью. В практике встречались случаи гастрита, язвообразования. Для парентеральной формы препарата: при инфузии — неприятный привкус во рту, чувство дурноты, учащенное сердцебиение, повышение артериального давления (последние три в основном при быстром введении препарата).
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Один из немногих качественных российских препаратов. Большая ниша для применения: от врача общей практики до реанимации. При правильном применении в адекватной дозе хорошо переносится, в том числе у детей и стариков. Может применяться в сочетании с различными препаратами без особого риска.
В сравнении со многими лекарствами выигрывает по соотношению цена/качество.
Отзывы пациентов о цитофлавине
Хороший препарат, знаю, что многим при нарушениях кровоснабжения помогает, но у меня после него пропало обоняние. Пришлось отменить, в качестве замены колола "Мексидол", а потом принимала в таблетках, хорошо зашел и постепенно улучшил кровоснабжение.
Прокапали "Цитофлавин" два дня. С вечера первого дня пошла побочка: повысилось давление, появилась тревога, удушье, заболел живот. Возможно, переборщили с дозой или слишком быстро капали. В понедельник снова пойду на дневной стационар. Буду жаловаться врачу на побочки. Кстати, прямое действие препарата отличное.
Мне "Цитофлавин" не подошел, головные боли усилились, поэтому я его бросила принимать. Стало значительно легче только после курса другого препарата.
Не удалось оценить препарат, т.к. успел вызвать сильнейшее обострение подагры. После отмены симптомы исчезли за пару дней.
"Цитофлавином" пользуемся всей семьей. Наша мама (ей 57 лет) перенесла ишемический инсульт и старается курсами 2 раза в год получать этот препарат в системе. В дневном стационаре поликлиники. После его применения у нее уменьшаются головные боли, головокружение, улучшается двигательная активность, улучшается память, появляется прилив сил. У меня самой вегето- сосудистая дистония. Страдаю от слабости, переутомления, частых стрессовых ситуаций. Пью "Цитофлавин" в таблетках в течении 1 мес. Работоспособность после него лучше улучшается, как умственная так и физическая, появляется бодрость. Мы довольны препаратом, побочных действий от него от него особых не было, если не принимать его натощак. А лучше после еды.
Формы выпуска
| Дозировка | Фасовка | Хранение | Продажа | Срок годности | |||
|---|---|---|---|---|---|---|---|
| 5; 10 |  |
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50; 100 | |
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Инструкция по применению цитофлавинаФармакологияМетаболический препарат. Фармакологические эффекты обусловлены комплексным действием компонентов, входящих в состав препарата Цитофлавин ® . Янтарная кислота — эндогенный внутриклеточный метаболит цикла Кребса, выполняющий в клетках организма универсальную энергосинтезирующую функцию. При участии кофермента флавинадениндинуклеотида (ФАД) янтарная кислота митохондриальным ферментом сукцинатдегидрогеназой быстро трансформируется в фумаровую кислоту и далее в другие метаболиты цикла трикарбоновых кислот. Стимулирует аэробный гликолиз и синтез АТФ в клетках. Конечным продуктом метаболизма янтарной кислоты в цикле Кребса является двуокись углерода и вода. Янтарная кислота улучшает тканевое дыхание за счет активации транспорта электронов в митохондриях. Инозин является производным пурина, предшественником АТФ. Обладает способностью активировать ряд ферментов цикла Кребса, стимулируя синтез ключевых ферментов-нуклеотидов — ФАД и НАД. Никотинамид (витамин РР), амид никотиновой кислоты. Никотинамид в клетках, путем каскада биохимических реакций, трансформируется в форму никотинамидадениннуклеотида (НАД) и его фосфата (НАДФ), активируя никотинамид-зависимые ферменты цикла Кребса, необходимых для клеточного дыхания и стимуляции синтеза АТФ. Рибофлавин (витамин В2) является флавиновым коферментом (ФАД), активирующим сукцинатдегидрогеназу и другие окислительно-восстановительные реакции цикла Кребса. Таким образом, все компоненты препарата Цитофлавин ® являются естественными метаболитами организма и стимулируют тканевое дыхание. Метаболическая энергокоррекция, антигипоксическая и антиоксидантная активность препарата, определяющие фармакологические свойства и лечебную эффективность составляющих, обусловлена взаимодополняющим действием янтарной кислоты, инозина, никотинамида и рибофлавина. ФармакокинетикаЦитофлавин ® обладает высокой биодоступностью. Янтарная кислота при приеме внутрь абсорбируется из ЖКТ, поступает в кровь и ткани, участвуя в реакциях энергетического обмена, и полностью распадается до конечных продуктов обмена (двуокись углерода и воду) через 30 мин. Инозин хорошо абсорбируется из ЖКТ. Tmax в крови составляет 5 ч, среднее время удержания в крови — 5.5 ч, Vd в равновесном состоянии — около 20 л. Инозин метаболизируется в печени с образованием инозинмонофосфата с последующим его окислением до мочевой кислоты. В незначительном количестве выводится почками. Никотинамид быстро распределяется во всех тканях (Vd в равновесном состоянии — около 500 л). Tmax в крови составляет 2 ч, среднее время удержания в крови — 4.5 ч. Метаболизируется в печени с образованием N-метилникотинамида. Выводится почками. Никотинамид проникает через плацентарный барьер. Проникает в грудное молоко. Рибофлавин быстро абсорбируется из ЖКТ, распределяется неравномерно (наибольшее количество в миокарде, печени, почках), трансформируется во флавинаденинмононуклеотид (ФМН) и ФАД в митохондриях. Проникает через плацентарный барьер. Выделяется с грудным молоком. Выводится почками, преимущественно в виде метаболитов. Форма выпускаТаблетки, покрытые кишечнорастворимой оболочкой красного цвета, круглые, двояковыпуклые; на поперечном срезе видны два слоя; ядро таблеток от желтого до желто-оранжевого цвета. |
| 1 таб. | |
| янтарная кислота | 300 мг |
| инозин (рибоксин) | 50 мг |
| никотинамид | 25 мг |
| рибофлавина фосфат натрия (рибофлавин) | 5 мг |
Вспомогательные вещества: повидон — 8.1 мг, кальция стеарат — 3.9 мг, гипромеллоза — 3.6 мг, полисорбат 80 — 0.4 мг.
Состав кишечнорастворимой оболочки: сополимер метакриловой кислоты и этилакрилата [1:1] — 29.02 мг, пропиленгликоль — 2.91 мг, краситель азорубин (кармуазин) (E122) — 0.07 мг.
10 шт. — упаковки ячейковые контурные (5) — пачки картонные.
10 шт. — упаковки ячейковые контурные (10) — пачки картонные.
Дозировка
Цитофлавин ® назначают по 2 таб. 2 раза/сут с интервалом 8-10 ч. Рекомендуется принимать препарат утром и днем, не позднее 18 ч.
Таблетки следует принимать не менее чем за 30 мин до еды, не разжевывая, запивая водой (100 мл).
Продолжительность курса лечения составляет — 25 дней. Назначение повторного курса возможно с интервалом не менее 1 месяца.
Передозировка
Взаимодействие
Янтарная кислота, инозин и никотинамид, входящие в состав препарата Цитофлавин ® , совместимы с другими лекарственными средствами.
Рибофлавин, входящий в состав препарата Цитофлавин ® , уменьшает активность некоторых антибиотиков (тетрациклинов, эритромицина, линкомицина), несовместим со стрептомицином. Этанол, трициклические антидепрессанты, блокаторы канальцевой секреции снижают абсорбцию рибофлавина, а тиреоидные гормоны ускоряют его метаболизм.
Побочные действия
Со стороны ЦНС: возможно — головная боль.
Со стороны пищеварительной системы: возможно — боли или дискомфорт в эпигастральной области.
Аллергические реакции: возможно — гиперемия кожи, зуд.
Со стороны обмена веществ: возможно — транзиторная гипогликемия, гиперурикемия, обострение сопутствующей подагры.
Пациент должен обратиться к врачу при усугублении любых из указанных или появлении новых побочных эффектов.
Показания
В составе комплексной терапии у взрослых:
- последствия инфаркта мозга;
- цереброваскулярные заболевания (церебральный атеросклероз, гипертензивная энцефалопатия);
- неврастения (повышенная раздражительность, утомляемость, утрата способности к длительному умственному и физическому напряжению).
Противопоказания
- детский и подростковый возраст до 18 лет (в связи с недостаточностью данных об эффективности и безопасности);
- повышенная чувствительность к компонентам препарата.
С осторожностью следует назначать препарат пациентам с заболеваниями органов пищеварения (эрозии, язвы желудка и/или двенадцатиперстной кишки, гастриты, дуодениты) в фазе обострения, с артериальной гипотензией, при нерфролитиазе, сопутствующей подагре, гиперурикемии.
Особенности применения
Применение при беременности и кормлении грудью
Не рекомендуется применять Цитофлавин ® при беременности и в период лактации, в связи с отсутствием клинических данных по эффективности и безопасности препарата у этой категории пациентов.
Применение при нарушениях функции почек
Применение у детей
Противопоказан в детском и подростковом возрасте до 18 лет.
Особые указания
При артериальной гипертензии может потребоваться коррекция доз гипотензивных препаратов.
У больных сахарным диабетом лечение следует проводить под контролем концентрации глюкозы в крови.
В период лечения возможно интенсивное окрашивание мочи в желтый цвет.
Влияние на способность к вождению автотранспорта и управлению механизмами
Цитофлавин ® не оказывает влияния на способность к управлению транспортными средствами, к работе с движущимися механизмами; на работу диспетчеров и операторов.
Отрицательные отзывы
Поставила одну капельницу — думала что помру, так было плохо — вначале то место где стояла капельница затвердело, покраснело и онемело потом появилась слабость, заболела голова, всю ночь не спала и было очень жарко, утром давление поднялось 150/100 (я гипотоник мое рабочее давление 100/60)появилас ь сухость во рту и такое чувство как будто мозги отделились от черепа стала чувствовать всю поверхность мозга от бровей до макушки. Больше ни когда не буду принимать этот препарат.
Принимала препарат "Цитофлавин"нед елю и чувствовала себя очень плохо: сердце болело постоянно, слабость ,болела голова, и всю трясло. Когда перестала принимать-все прошло.
Мне ставили капельницы Цитофлавина, сделали 6 капельниц, эффекта никакого я не почувствовала. Поставили еще 4 капельницы, так началась такая головная боль, что ели вытерпела, поднялась давление, во рту сухость, думала помру. Перестали делать капельницы, врач сказал пить в таблетках, стала пить в таблетках, эффекта 0. Так к тому же сдала анализ крови и норма щелочной фосфатазы была преувеличена в 4 раза, пострадала печень. Так я потом еще и лечила печень. Цитофлавин стоит немалых денег, а смотрю отзывы о нем либо нет положительного результата, вообще не помогает, либо ухудшает состояние. Какой смысл?
Принимала В/капельно Цитофлавин. Побочное действие — при анализе крови показатель щелочной фосфатазы превысил норму в 6 раз, т. е. в результате действия лекарства сильно пострадала печень. Сейчас лечу печень. А от Цитофлавина результата никого не почувствовала. Советую отказываться от этого препарата, который врачи очень сильно рекомендуют. Он вредит здоровью
ужасный препарат! Сильно понижает уровень глюкозы-аппетит зверский ,очень сильно стали болеть коленные суставы(не зря же противопоказания-подагра) и аллергия на 5-й день сильнейшая! А положительного эффекта абсолютно никакого! Категорически не рекомендую.
Достоинства:
Недостатки:
Цена, отсутствие эффекта, побочные эффекты.
Два раза пообщался с этим препаратом и оба общения положительных впечатлений не добавили. Узнав, что и голова иногда побаливает, ухудшение слуха ЛОР свалил на кровообращение в голове и на невролога, а тот прописал цитофлавин с актовегином. Цитофлавин в виде капельниц — 10 штук, а по окончании капельниц, вводил внутривенно актовегин. Правда после первой же процедуры пришлось прекратить, словил побочные. И рука начала то чесаться то болеть и головокружение на утро и локоть ныл 4 дня и общее самочуствие только ухудшилось. Но врач настаивал на приеме и решил перейти на таблетки. Пропил целый курс. В отличии от капельницы, никаких побочных действий. Правда и эффекта тоже нет. Причем не только слух не улучшился, но и голова меньше болеть не стала. Копеечный цитромон и то от головной боли помогает лучше. Не знаю почему врачи любят назначать цитофлавин, я ни кому не рекомендую. Дорогой и бесполезный.
Достоинства:
Недостатки:
Всем здравствуйте!
Начну с предыстории: после родов мой организм сдал, внезапно начались сильнейшие головные боли, депрессия. Невролог изначально предположил что у меня нарушение кровообращение в мозге, поэтому назначил таблетки Цитофлавин. Пропила их курсом 25 дней. Параллельно сделала дуплексное сканирование и МРТ. Нарушение кровообращения не подтвердилось.
По поводу их приема хочу сказать: они мне ничем не помогли. Головная боль не прошла и настроение не улучшилось.
Никаких побочных эффектов не было. Можете спокойно принимать, если вам их назначили.
Считаю, что для препарата в стоимостью 700 рублей, он оказался слишком неэффективным 🙁
Нейтральные отзывы
Преимущества: Качество, цена.
Недостатки: Инъекции, капельницы.
После перенесённого инфаркта мозга, врач назначил моей матери применять капельницы из Цитофлавина и уколы его же в комплексе с виноградным соком, чтобы как-то возвратить нормальную циркуляцию крови в мозгу. В нём много витаминов и полезных ингредиентов, схож чем-то с эффектом плацебо. Можно применять комплексно, например с янтарной кислотой и фолиевой. Помогает снять чувство тревоги и головные проблемы, тонизирует и закаляет иммунитет организма, убирает головные боли, приводит в норму циркуляцию крови. Немного меняет состав крови — это его побочное действие. В целом, препарат стоящий и по цене, и по качеству. Главное, что принимать нужно полный курс, не прерывая.
Цитофлавин (Cytoflavin) — препарат имеющий противоречивую историю и отзывы. Широко используется в медицине для улучшения кровообращения. Могу сказать, что показал свою эффективность при приеме после инсульта. Если успеть ввести его в течении 12 часов после приступа, то ишемические и некротические процессы в поражённой зоне пройдут значительно мягче. Это ускорит выздоровление.
Принимала препарат в таблетках для улучшения мозгового кровообращения (без назначения врача). Результат: мигренеподобные боли стали реже, настроение улучшилось, нервное напряжение спало, на работе стала меньше уставать. Прошла мышечная астения и с нею прошли боли в мышцах спины. Первые дни наблюдалась реакция в виде лёгкого покалывания в руках и ногах. После покалывания по телу разливалось тепло и неприятные ощущения проходили. НИКАКИХ ПОБОЧЕК У МЕНЯ НЕ БЫЛО. Плохо одно- после завершения курса приёма, вновь почувствовала, как наваливается напряжение и возвращается усталость. Не подсела ли я на них?!
данный препарат я как врач рекомендую людям после 50 когда есть признаки атеросклероза мозговых сосудов. это снижение памяти,шум в ушах.он бесполезен когда человек находится в маразме и махровом атеросклерозе-когда все "кружится",а у молодых головокружение и пошатывание связано чаще с шейным остеохондрозом и вегето сосудистой дистонией,поэтому их и надо лечить!!препарат пьют курсами 2-3 раза в год по 1-2 месяца,он реально отодвигает маразм и атеросклероз при курсовом регулярном приеме
Достоинства:
Недостатки:
помогает, но не всем
Добрый день, а возможно и вечер дорогие читатели моего отзыва!
Сегодня я хочу немножко написать о новом препарате, который появился в аптечке моего мужа это — Цитофлавин. Наблюдая за мужем во время применения этого препарата могу сказать только одно, что пока я улучшения его самочувствия не вижу никакого, как он себя не хорошо чувствовал так и сейчас продолжает болеть, несмотря на назначения врача. Муж принимает эти таблетки уже третью неделю, голова по-прежнему болит, к тому же давление скачет. Говорю мужу не принимать это лекарство больше, а он придерживается рекомендации врача курс лечения ведь таблетками длится месяц, вот и терпит. А если терпит значит чувствует себя лучше.
Таблетки выпускаются в удобном блистере по 10 штук, купить можно в любой аптеке, известный препарат искать долго не нужно.
Так что, настаивать применять во время болезни этот препарат или нет решать только Вам, ведь я не доктор, но лучше всего постараться не болеть вообще.
Будьте здоровы!
Положительные отзывы
Здравствуйте! Моя работа связана с мозговой активностью. За мой многолетний опыт работы, частые недосыпания и прочие причины, активность мышления упала. В буквальном смысле я плохо стал соображать и частенько болела голова. Параллельно с этим появлялись мелкие проблемы во всем организме, но до того, как я попробовал препарат Цитофлавин. В описании пишется, что препарат улучшает мозговой метаболизм. По своему личному опыту я особых ощущений во время приёма не испытал, но умственные проблемы больше не беспокоят. Соответственно, готов поставить хорошую оценку данному препарату, он с задачей справился и улучшил мое состояние.
Принимала Цитофлавин в таблетках в комплексной терапии. Очень понравилось. Положительное действие оказал не только по прямому назначению, но и на суставы, желудок, общее самочувствие. Вчера сходила попросила врача опять назначить.
На 5 ампул хватило! Пенсия маленькая! При необратимой дегенерации (разрушение) тканей мозга, которая была вызвана травматическим воздействием. И месяц голова не так болела и скорую не вызывали.Приступы меньше стали давить.
Достоинства:
хоть и небольшой, но эффект есть
Недостатки:
Назначили данный препарат при грыже диска шейного отдела позвоночника, с5-с6 6.5 мм. Ставили в виде капельниц — 10 штук, а по окончании капельниц, вводил внутривенно актовегин. Состояние начало улучшаться буквально после первой капельницы. Мушек в глазах стало меньше, ясная голова, уменьшилось головокружение. Никаких побочных действий данный препарат на меня не оказал, ни во время приема, ни после. Абсолютно безопасный препарат, правда и эффект не значительный. Не знаю почему наши неврологи так любят назначать цитофлавин и актовегин — в развитых странах это или не применяется или считается научно не доказанными препаратами . Главное, что вреда не нанесло — так что можно применять по назначению врача.
Достоинства:
Высокий уровень эффективности при перегрузках, отсутствие побочных эффектов
Недостатки:
Это лекарство фактически является витаминным комплексом, но только витамины здесь подобраны так, чтобы наилучшим образом воздействовать на работу головного мозга.
Случилось так, что мне пришлось очень много и напряжённо работать. И работа эта была отнюдь не физической. После защиты диссертации я почувствовала себя очень слабой, стала страдать память, трудно было сосредоточиться. Поскольку невропатолог не нашёл в моей голове никакой патологии, он прописал лекарства, способные восстановить мою работоспособность.
После первых десяти дней приёма цитофлавина мне стало значительно легче. Я постепенно возвращалась к нормальной жизни.
Через две недели я почувствовала себя вполне здоровым человеком, снова готовым к трудовым интеллектуальным подвигам. Так что спасибо цитофлавину. Приятно ещё и то, что у него практически нет побочных эффектов, кроме, конечно, гипотетической аллергии.
Достоинства:
Есть результат, думала уже ни чего не поможет, рекомендую!
Недостатки:
Очень хороший препарат. Назначила невролог, головные боли были каждый день, замучилась. Обезболивающие не помогали, пропила курс цитофлавина 25 дней, результат уже дней через пять. Головные боли прошли, состояние улучшилось. Сама гипертоник, жировик в головном мозге, пропила в декабре, сейчас бывают головные боли, но редко. думаю еще курс пропью.
Данный препарат мне выписал невролог после длительной болезни, повлиявшей на общее состояние организма и нервной системы. Описывая вкратце, скажу, что испытывала постоянную усталость, слабость, иногда головокружения. Организм уже пошел на поправку, но было ощущение, что дополнительная помощь ему все таки нужна, плюс я склонна к понижению давления, что и так часто делает меня не очень бодрой (кофе могу пить ведрами .
Итак, после двух дней приема препарата по 2 таблетки 2 раза в день за 30 минут до еды, в общем как в инструкции, что-то не очень комфортно стал себя чувствовать мой желудок. Далее на 3й день я допустила ошибку, забыв выпить вторую дозу таблеток в необходимое время и приняв в 8 часов вечера. Плюс в тот день выпила пару чашек кофе. Как же плохо мне было ночью. Болело то в области сердца, то в какой-то одной точке головы, спала плохо и беспокойно, утром встала какая-то перевозбужденная, но, конечно же, ко второй половине дня стала разваливаться от усталости. Прием препарата прекратила и возобновила спустя несколько дней. Только теперь я пью 2 таблетки 1 раз в день утром натощак. Конечно, чтобы избежать побочек на желудок можно принимать во время еды (говорил мне доктор), но эффективность может снизится, или же строго по времени и до 6 вечера, но я решила не рисковать и сама себе снизила дозу Сейчас мое состояние почти в норме, и нет критичной потребности в этом препарате, однако пачка уже куплена (не дешевая нужно признать), и я решила ее разделить на два курса, таки по 2 таблетки 1 раз в день. Мои ощущения, что препарат слишком сильный для меня, хоть и по большей части это витамины.
Соответственно, мои субъективные минусы:
2) Побочные эффекты в виде дискомфорта в желудке, перевозбуждения и головной боли
3) Не удобный график приема (легко забыть)
Из плюсов:
1) Ощутимый эффект
Спешу поделиться своим открытием. Уже много лет страдаю от ВСД, чего только не принимала, и от большинства препаратов болит голова (мелоксикам, фенибут и др.). Тут весной заболела, непонятно чем. Температура 37, СОЭ высокое. Врач прописала таблетки Найз. и вдруг перестала болеть шея, хотя я даже не подозревала что она и болит.
Сделали рентген — оказался шейный остеохандроз. Врач говорит, что ВСД+остеохандроз дает целый букет болячек вплоть до острого инсульта, так как сосуды и без того хилые, да еще позвонками пережимаются.
Прописала попробовать "Цитофлавин". Стоимость около 300 рублей. Принимать нужно по 2 таблетки два раза в день, с интервалом 8 часов. При этом вторую таблетку нужно выпить не позднее 6 часов вечера, иначе спать не будешь.
Мне препарат подошел идеально. Принимала по такой схеме. За месяц приема голова болела всего два раза, а для меня это огромное достижение, потому что обычно в месяц от головной боли упаковку анальгина съедаю. А тут два раза. Один раз перед ветром, второй раз во время ПМС. Была отличная устойчивость к стрессам, глаза смотрели на мир трезво и оптимистично.
И такой "побочный эффект" — кожа на лице буквально разгладилась, морщинки ушли и кожа очень хорошо выглядела. Хотя про это нигде ничего не сказано, но я так понимаю, что из-за гипоксии страдает же не только мозг, но и все остальные органы тоже.
Мой "синдром раздраженного кишечника" тоже не беспокоил.
Обязательно после консультации с врачом повторю курс.
По фармакологическому действию цитофлавин это метаболическое средство. Стимулирует все внутренние процессы, улучшает мозговой кровоток.
Это лекарство мне выписал врач невролог от неврастении
(повышенная раздражительность, утомляемость, утрата способности к длительному умственному и физическому напряжению).
До такого состояния я себя довела стрессами, переработками и прочими неприятностями.
Врач прописала капельницу или уколы с этим лекарством в виду эффективности, но с уколами я не дружу с детства. Сошлись на таблетках.
За 50 таблеток я заплатила около 400-500 рублей.
Способ применения и дозы
Внутрь по 2 таблетки 2 раза в сутки с интервалом между приёмами 8–10 часов. Таблетки следует принимать не менее чем за 30 минут до еды, не разжёвывая, запивая водой (100 мл).
Рекомендован приём препарата в утреннее и дневное время суток (не позднее 18 часов).
Продолжительность курса лечения 25 дней. Назначение повторного курса возможно с интервалом не менее 1 месяца.
Таблетки красного цвета, небольшие. Проблем с проглатыванием не возникало. Разве что сложно было с принятием таблеток с утра за полчаса до завтрака. Но вроде выработала алгоритм))
Через несколько дней заметила результат, у меня повысилось настроение, жизненный тонус, появились силы и желание что-то делать.
Конечно после прекращения приема все это постепенно стало сходить на нет, но с этими таблетками я дотянула до отпуска и мне стало намного легче)))
Планирую в ближайшем времени повторить курс.
Лекарственным препаратом, который восполняет дефицит биологически активных веществ и витаминов в организме, способствует улучшению функционирования нервной системы, является Цитофлавин. Перед началом приема важно изучить все рекомендации производителя, которые содержит инструкция по применению. Данная статья дополнена отзывами врачей и больных, а также актуальными ценами и существующими аналогами Цитофлавина в России.
Состав
Медицинский препарат Цитофлавин (на латыни международное название — Citoflavini) содержит комплекс активных действующих веществ:
- Янтарная кислота — 300 мг в таблетках и 100 мг в 1 мл раствора;
- Рибоксин — 50 мг в таблетках и 20 мг в 1 мл раствора;
- Никотинамид — 25 мг в таблетках и 10 мг в растворе;
- Рибофлавин — 5 мг в таблетках и 2 мг в растворе.
Дополнительные ингредиенты в составе препарата следующие:
- повидоны;
- стеараты Ca;
- производные целлюлозы;
- полисорбаты;
- полимеры;
- ПЭГ;
- вода стерильная (ампулы);
- гидроксид Na;
- меглюмин.
Форма выпуска
Производитель Polisan (Россия) представляет на рынке лекарство Цитофлавин в двух формах выпуска:
- таблетки c оболочкой красного цвета с желтым ядром внутри. В каждой упаковке — по 50 таблеток;
- раствор (концентрат, ампула по 10 мл) для инфузий, который имеет желтое окрашивание. В упаковке по 5 или 10 ампул.
В каждую оригинальную упаковку вкладывается официальная инструкция по применению.
Фармакологическое действие
Цитофлавин относят к фармакологической группе препаратов, применяемых для терапии неврологических расстройств и заболеваний. Благодаря сбалансированному уникальному составу и механизмам действия отдельных ингредиентов достигаются разнообразные формы фармакологического и терапевтического действия:
- стимуляция клеточного дыхания;
- увеличение синтеза энергии внутри клеток;
- улучшение поглощения кислорода клетками;
- антиоксидантный эффект;
- активизация внутриклеточного метаболизма;
- улучшение циркуляции крови в миокарде и сосудах головного мозга;
- стимуляция мыслительных функций;
- устранение рефлекторных отклонений;
- возбуждающее влияние после наркоза;
- уменьшение площади некротических и ишемических очагов после инсульта;
- ускорение реабилитации после тяжелых неврологических болезней.
Показания к применению
Препарат применяется с новорожденности у детей с целью коррекции церебральной формы ишемий мозга и с целью ускорения процессов восстановления после преждевременных родов.
Показаниями к применению у взрослых пациентов являются следующие патологии:
- острые формы нарушений кровотока в мозге;
- энцефалопатия разной степени и формы;
- ишемические поражения мозга хронической формы;
- атеросклероз церебральных сосудов;
- астения;
- нарушения циркуляции крови при патологиях позвоночника и остеохондрозе.
Противопоказания
Цитофлавин не назначают при наличии таких нарушений, являющихся противопоказаниями к применению:
- аллергия;
- подагра;
- нефролитиаз;
- критическое состояние пациента, кроме новорожденных;
- гиперурикемия.
Важно! Перед тем, как делать назначение Цитофлавина, важно исключить указанные патологические состояния.
Инструкция по применению
Способы применения раствора:
Приготовление растворов и способы введения: содержимое ампулы следует растворить в 100-200 мл NaCl 0,9% или глюкозы 5-10%. Вводится только внутривенно при помощи капельниц.
Дозирование при энцефалопатиях: при всех формах, кроме токсических вводят 10 мл Цитофлавина в сутки 10 дней. При токсических формах — по 10 мл дважды в день 5 суток подряд.
При коме вводится по 20 мл Цитофлавина на одну инъекцию. Введение дважды в день 10 суток подряд.
При нарушениях кровотока доза составляет 10 мл Цитофлавина 1 раз в сутки 10 дней.
Применение у новорожденных и недоношенных детей: рекомендовано начинать терапию в первые 2 часа после рождения ребенка. Рекомендуют разводить препарат в растворах глюкозы 5-10%. Дозировка лекарства — 2 мл на 1 килограмм веса ребенка в сутки. Скорость введения — 1-4 мл в час. Продолжительность курса лечения — 5 суток.
Схема приема в форме таблеток:
Принимать следует только внутрь за 30 минут до еды. Запивают не менее 10 мл чистой воды.
Рекомендованная доза — по 2 таблетки дважды в сутки. Интервал между приемами — от 8 до 12 часов. Время приема следует подобрать так, чтобы первая доза была принята утром (до обеда), а вторая — вечером (после обеда), но не позднее 18-00. Длительность приема Цитофлавина в таблетках — не менее 25 суток. Повторный курс возможен спустя 30 суток после окончания предыдущего.
Передозировка
По описанию производителя не выявлено случаев передозировки. Предполагается, что последствиями передозировки могут быть усиление побочных эффектов. Способы оказания помощи пациенту — только симптоматические.
Побочные действия
Нежелательные реакции на прием препарата — крайне редкое явление. Возможными побочными действиями считаются следующие:
- перевозбуждение;
- нарушения сердечного ритма;
- учащенное сердцебиение;
- отеки на коже;
- бледность кожных покровов;
- одышка;
- рвота;
- отрыжка;
- кожные проявления аллергии;
- желтая окраска мочи;
- чувство жара.
В детском возрасте возможны нарушения равновесия электролитов в организме.
Взаимодействие с другими средствами
Возможно усиление эффективности при комбинации с такими средствами:
- сердечные гликозиды;
- гепарин.
Снижение эффективности препарата отмечается при совместимости с такими средствами:
- алкалоиды;
- танины;
- кислоты;
- спирты;
- Пиридоксин;
- антидепрессанты;
- Амитриптиллин;
- Хлорпромазин;
- Имизин;
- гормоны щитовидной железы.
При беременности и лактации
Цитофлавин при беременности применяют только в случае превышения пользы над рисками. Возможности назначения Цитофлавина при грудном вскармливании (ГВ) в период лактации определяет только лечащий врач. В аннотации производителя нет указаний о безопасности применения Цитофлавина при кормлении грудью.
С алкоголем
При взаимодействии с алкоголем происходит снижение эффективности препарата. Важно помнить, что Цитофлавин и алкоголь характеризуются очень низкой совместимостью. На период лечения обязательно исключить спиртные напитки.
Аналоги
Не существует прямых заменителей Цитофлавина (янтарной кислоты в ампулах) по действующим веществам. Препарат при острой необходимости можно заменить на препараты, оказывающие похожее действие на нервную системы. К таким синонимам можно отнести Нуклео-ЦМФ, Инстенон, Винпоцетин, Кавинтон, Глутаминовую кислоту, Мексидол (отечественный российский аналог Цитофлавина). Нередко назначают комбинацию Цитофлавина с указанными средствами. Вводить Цитофлавин и Мексидол одновременно (в одном шприце) не рекомендуется. При совместном назначении следует выдерживать интервал между инъекциями.
Важно! Замена проводится только врачом.
Цитофлавин отличается от указанных препаратов уникальным составом.
Срок годности
Независимо от форм выпуска Цитофлавин хранится 2 года, начиная с даты выпуска. После завершения указанного срока годности запрещено применение лекарства.
Условия продажи и хранения
С целью сохранения свойств и эффективности препарата важно соблюдать следующие условия хранения:
- температура — не более 25⁰С;
- вдали от доступа детей;
- без доступа света.
Цитофлавин отпускают из аптеки только по рецепту (на латинском) с указанием МНН активных ингредиентов или препарата.
Особые указания
Применение препарата у новорожденных важно совмещать с регулярным контролем кислотно-щелочного состава крови. При нарушениях дыхания введение Цитофлавина можно прекратить временно или снизить скорость инфузий.
При развитии головокружений следует избегать вождения автомобиля. Препарат вводится внутривенно только в условиях отделения.
Стоимость препарата зависит от формы выпуска:
- таблетки №50 стоят от 380 рублей;
- ампулы №5 — от 520 руб.;
- ампулы №10 — от 1040 руб.
Отзывы
Михаил И.: у меня доктор лечит последствия инсульта (восстановление, часто болит голова и т.д.). Назначил Цитофлавин в таблетках для ускорения реабилитации и профилактики осложнений и еще некоторые уколы внутримышечно. Препарат очень эффективный, в отличие от аналогов дешевых (российских). Цитофлавин имеет разницу в составе, там очень продумано соотношение компонентов, поэтому после инсульта средство намного эффективнее, чем другие похожие лекарства (которые могут стоить дешевле). Несмотря на то, что у меня гастрит, это средство мне разрешено принимать.
Сергей П.: принимаю Цитофлавин в таблетках 3 недели при энцефалопатии. Очень доволен эффектами. Симптомы мягко и постепенно уходят. Доктор назначил принимать месяц. Мне назначают это лекарство не впервые. Каждый курс лечения результат очень хороший.
Ольга Платонова, невролог: часто приходится назначать Цитофлавин, в том числе маленьким детям. Хочется отметить, что препарат действительно помогает устранить нарушения церебрального кровотока, функционирования нервной системы и улучшить состояние даже «тяжелых» больных. Побочные эффекты развиваются очень редко.
Кирилл Тимчуков, невролог: в списке одних из лучших препаратов для лечения неврологических патологий — Цитофлавин. Широкий спектр активности, высокая безопасность, возможность назначать детям и беременным — вот основные достоинства препарата. По результатам применения у пациентов могут сказать, что Цитофлавин «работает» при многих, даже очень серьезных заболеваниях.
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