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Что показывает кровь на биохимию

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17 августа 2019

Одним из самых информативных и доступных лабораторных анализов является биохимия крови. Метод помогает определить состояние внутренних органов человека и выявить развитие патологических отклонений на ранних стадиях. Оценка обменных процессов и потребность организма в конкретных микроэлементах также определяется с помощью биохимического анализа.

Биохимический анализ крови отличается высокой информативностью

Содержание

Показания к сдаче биохимического анализа крови

Любое обследование (специальное или с целью профилактики) начинается со сдачи биохимического анализа крови (БАК).

Частыми показаниями для проведения исследования выступают:

  • печёночные и почечные патологии;
  • отклонения в нормальном функционировании сердца (ишемия, недостаточность, инфаркт, инсульт);
  • болезни мочеполовой системы (воспалительные процессы различной этимологии);
  • эндокринные патологии (сахарный диабет, нарушение работы щитовидки);
  • сбои в нормальной деятельности пищеварительного тракта (язвенные или воспалительные процессы в желудке, кишечнике, двенадцатиперстной кишке, поджелудочной железе);
  • патологические изменения в позвоночнике, суставах и мягких тканях (остеохондроз, артроз, артрит, бурсит, остеопороз).

В обязательном порядке БАК назначают во время беременности, перед любой предстоящей операцией, при ежегодных профосмотрах.

Сдавать кровь на биохимию нужно при ишемической болезни сердца

Что входит в биохимию?

В зависимости от индивидуальной ситуации анализ включает определённое количество компонентов. Такое бывает, когда нужно устанавить причину нарушения работы конкретного органа. В случае расплывчатой клинической картины состояния больного или для более детального изучения проблемы нужно проводить развёрнутый БАК.

Таблица «Основные показатели полного биохимического анализа крови»

Составляющие Описание
Гемоглобин Выполняет транспортную функцию (доставляет кислород во все клетки организма) и способствует нормальному кроветворному процессу
Билирубин прямой, конъюгированный (IDBIL) Прямой (указывает уровень оттока желчи). Повышается при воспалении печени, застойных процессах в желчном, нарушении транспортировки прямого билирубина из желчи в кровь
Непрямой билирубин (DBIL) Свидетельствует о серьёзных нарушениях в печени
Глюкоза (GLU) Контроль сахара в крови, оценка метаболизма углеводов
Креатинин Отображает функционирование почек и способствует нормальному энергетическому обмену в тканях
Мочевина (urea) Утилизируется почками, показывает уровень их работоспособности. Именно при заболеваниях почек мочевина сильно отклоняется от нормы
Мочевая кислота (uric acid) Концентрат солей натрия. Выводится с мочой и калом. Если большое количество сосредоточено в крови, речь идёт о нарушении пуринового обмена (закупорка солями сосудов, косной и мышечной ткани)
АСТ (аспартатаминотрансфераза) и АЛТ (аланинаминотрансфераза) Преимущественно синтезируется в печени, в кровь попадает при разрушении тканей органа
Холестерин (chol) Показатель жирового обмена. Повышенное количество отображает нарушения в сердце или сосудах, а также может свидетельствовать о развитии онкологических опухолей
Общий реактивный белок (tprot) Строительный компонент, отвечает за нормальные обменные процессы в крови и тканях организма
Альбумин Основные белки крови. Позволяют конкретнее определить заболевание, чем значения общего протеина. Повышение показателей может указывать на потерю жидкости организмов, нарушения работы сердца, проблемы с почками
Глобулин
Фибриноген
Триглицериды (trig) Основной источник энергии для клеток внутренних органов. Увеличение показателя может указывать на проблемы с сердцем или сосудами, гепатитом или циррозом печени, избыточной массой тела, подагрой
Электролиты

Хлор

Участвуют в водно-электролитном обмене. Ревматоидный фактор Фермент свидетельствует о развитии в организме артрита, ревматизма, артроза Амилаза (альфа-амилаза и панкреатическая амилаза) Отображает работу желудочно-кишечного тракта. При увеличении значений говорят о панкреатите, холецистите, перитоните. Уменьшение количества амилазы может наблюдать во время вынашивания ребёнка

Целью развёрнутой биохимии является определение конкретного заболевания и оценка масштаба поражения соседних органов патологическими процессами.

Как подготовиться к исследованию крови

Результаты биохимического анализа крови во многом зависят от подготовки к процедуре.

Чтобы избежать искажённых данных, важно соблюдать несколько основных правил:

  1. Сдача биологического материала происходит натощак. Не употреблять пищу или напитки за 8–10 часов до манипуляции. Если нужно определить точный уровень сахара, не нужно чистить зубы и пить обычную воду без газа.
  2. Накануне анализа отказаться от вредной пищи – жирного, солёного, копчёного, острого, а также исключить прием крепкого кофе или чая.
  3. За 2–3 дня до исследования не употреблять спиртные напитки. А за час до процедуры – отказаться от курения.
  4. Не менее чем за сутки до анализа избегать тяжёлого умственного и физического труда, стрессов и эмоциональных перенапряжений.
  5. Забор биологического материала должен происходит в утреннее время перед всеми медицинскими процедурами (уколы, прием таблеток, капельницы, аппаратные действия).
  6. Употребление лекарственных средств нужно прекратить за 10–14 дней до сдачи крови. Если такой возможности нет, важно предупредить об этом врача.

Перед сдачей анализов нельзя пить чай или кофе

Как сдать кровь на биохимию

Особенность биохимического анализа в том, что для его проведения нужна кровь из вены.

Берут биологический материал следующим образом:

  • пациент усаживается за столик, располагая правую (левую) руку перед собой на специальный валик;
  • на расстоянии 4-6 см выше локтя медсестра фиксирует хомут или резиновый шланг;
  • пациент начинает работать кулаком (сжимает, разжимает), а медсестра в это время определяет наиболее наполненную вену посредством пальпации;
  • место прокола обрабатывается ваткой со спиртом и вводится игла;
  • протягивая на себя поршень шприца, специалист набирает нужное количество биологического материала, в конце процедуры на место укола накладывается проспиртованная вата;
  • локоть нужно согнуть, и плотно держать ватный диск в течение 3–5 минут.

Процедура забора крови для БАК практически безболезненна и занимает не более 5 минут. В зависимости от загруженности специалистов, расшифровку анализа делают в течение 2–3 дней.

Расшифровка результатов и нормы

Интерпретация полученных значений биохимического анализа крови выдаётся пациенту на специальном бланке. Он представляет собой таблицу, в которой отмечены исследуемые показатели и их соотношение к нормальным значениям.

Таблица «Нормы биохимического анализа крови с учётом пола и возраста пациента»

Показатели Норма
У взрослых У детей
У мужчин У женщин
Общий белок, г/л 63–85 До года – 46–73

От 1 до 5 лет – 60–77

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От 6 до 8 лет – 53–79

От 9 до 15 лет – 57–78

Альбумин, г/л 35–45 40–50 Глобулин, г/л

2–2,4

Альфа1 Альфа2 1,55–3,52 1,77–4,20 4,5 Бета-глобулин 2,2–4 От рождения до 12 лет – 1,35–2,75 Гамма-глобулин До 10,5 Гемоглобин 130–160 118–145 Билирубин прямой, конъюгированный (IDBIL), мкмоль/л 0-7,9 Непрямой билирубин (DBIL), мкмоль/л До 19 Глюкоза (GLU), ммоль/л С 14 до 59 лет – 3,87–5,88

С 60 до 70 лет – 4,4–6,4

Больше 70 лет – 4,1–6,1

3,34–5,55 Креатинин, мкмоль/г 63-117 52-97 До года жизни – 17–36

От года до 14 лет – 26–63

Мочевина (urea), ммоль/г 0,22–0,55 0,14–0,46 От 0 до 14 лет -0,18–0,64 Мочевая кислота (uric acid), ммоль/г 0,16–0,56 0,13–0,47 От 0 до 14 лет – 0,15–0,32 Ферменты АСТ (аспартатаминотрансфераза), Ед/л До 40 До 35 От 0 до 12 месяцев – до 58

14–18 лет – до 40

АЛТ (аланинаминотрансфераза), Ед/л До 46 До 33 До 48 Холестерин (chol), ммоль/л До 5,2 Триглицериды (trig), ммоль/л С 15 до 45 лет – 0,45–3,62

С 45 до 60 лет – 0,65–3,23

С 60 до 70 лет – 0,66–2,94

С 15 до 45 лет – 0,40–2,16

С 45 до 60 лет – 0,52–2,96

С 60 до 70 лет – 0,63–2,71

До 10 лет – 0,33–1,22

С 10 до 15 лет – 0,37–1,49

Электролиты, ммоль/л

Витамин В12, по/мл

206–964

Ревматоидный фактор Отсутствует

Вопрос-ответ

Как улучшить биохимический анализ крови?

Улучшению состава крови способствуют специальные процедуры и мероприятия:

  • массаж (восстанавливает кровообращение, налаживает обменные процессы, стимулирует транспортировку кислорода по всем клеткам);
  • физические упражнения (регулярная утренняя зарядка, пешие прогулки на свежем воздухе, плаванье);
  • тёплые ванны (не только производят общерасслабляющее действие, но и способствуют очищению крови от токсинов и ядов;
  • правильное питание (больше употреблять овощей и фруктов в сыром, варённом и тушёном виде, исключить всё жирное, жареное, солёное и острое);
  • забыть об алкоголе и курении.

Соблюдая конкретные правила, в короткие сроки можно очистить кровь от вредных веществ, улучшить в ней водно-электролитный баланс и наладить метаболизм.

Чтобы оздоровить свою кровь употребляйте больше овощей

Чем отличается общий анализ крови от биохимического?

Биохимия крови представляет собой лабораторный метод диагностики, который позволяет оценить работу внутренних органов (почек, поджелудочной железы, желудка, кишечника, печени) и определить, каких микроэлементов не хватает для нормально функционирования той или иной системы. Такой вид исследования крови широко применяется в эндокринологии, терапии, гастроэнтерологии, кардиологии, урологии, гинекологии, так как реагирует на гормоны (нарушение гормонального фона), определяет количество сахара в плазме, выявляет печёночные ферменты.

Клинический анализ показывает только форменные элементы крови

Развёрнутый биохимический анализ крови достаточно информативен. Он широко применяется в медицинской практике, как для профилактики, так и в лечебных целях. Лабораторный метод показывает состояние внутренних органов, помогает выявить причину патологических нарушений на начальном этапе развития и определить нехватку полезных веществ в организме. Процедура забора крови занимает не больше 5 минут, а результаты можно получить уже на 2–3 день после процедуры.

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Все процессы в организме человека происходят в результате биохимических реакций. Переваривание пищи, работа эндокринных органов, обмен веществ и много другое регулируется специальными веществами и ферментами. Их количественный и качественный состав служит для врачей диагностическим признаком. Норма и расшифровка биохимического анализа крови указывается сразу в результатах анализа, когда пациент забирает их из лаборатории.

Как расшифровать у взрослых

Взрослый пациент получает результаты в течение нескольких дней после сдачи крови. Длительность ожидания зависит от количества показателей, которые проверяются, а также от сложности их выявления. Лаборатория выдает на руки распечатанную таблицу, в которой указаны нормы концентраций по каждому пункту, а рядом – выявленное количество у конкретного пациента. Выводы делаются путем сравнения нормы с фактическим результатом. Ненормальными являются как завышенные, так и заниженные показатели.

Следует знать, что норма многих исследуемых позиций зависит от пола и возраста пациента, поэтому важно сообщать правильные данные о себе перед прохождением исследования. Значение фактических показателей может меняться в какую-либо сторону при несоблюдении правил подготовки к исследованию – интенсивных занятиях спортом накануне, курении или употреблении алкоголя перед забором крови. При необходимости повторного анализа, проводить исследование нужно в той же лаборатории, чтобы сравнение было верным. Различные клиники могут получать результаты разными методами, из-за чего даже показатели нормы будут отличаться.

Расшифровка у детей

Результаты по каждому нужно смотреть с учетом возраста ребенка. Расшифровывать данные должен только специалист, обращая внимание на комплексную картину, а не на отдельный показатель. Поставить правильный диагноз помогут дополнительные обследования – УЗИ, анализ мочи, томография и другие.

Отклонение результатов от нормы может свидетельствовать о наличии врожденных патологий, развитии инфекционно-воспалительных процессов, а также о нарушении процедуры проведения анализа. Увеличение или уменьшение какого-либо показателя может быть временным или вызвано реальным заболеванием, поэтому повторный анализ рекомендуется поводить всегда.

Подготовка к анализу

Чтобы уменьшить вероятность искажения результатов анализа, пациенту необходимо соблюдать некоторые правила по подготовке к нему. Для исследования берется венозная кровь. Как правило, достаточно около 5 мл биоматериала, которые распределяют по нескольким пробиркам.

Вещества, которые определяют в биохимическом анализе, могут изменять свои свойства или количество под действием психоэмоционального состояния, из-за приема некоторых медикаментов, особенностей режима питания, физической активности и некоторых других факторов. Задача подготовки к исследованию состоит в исключении любых факторов, которые могут повлиять на реальный результат. Рекомендации для пациента будут следующими:

  • Сдавать кровь нужно натощак. Время воздержания от пищи должно быть 10-12 часов
  • Накануне исключается прием кофе и крепкого чая
  • За пару дней до сдачи биоматериала рекомендуется придерживаться щадящей диеты с исключением жирной, жареной, острой пищи и алкоголя
  • В предыдущий день рекомендуется вести умеренный и спокойный образ жизни, не прибегать к интенсивным физическим нагрузкам и не находиться в стрессовых ситуациях. Исключаются также тепловые процедуры — баня, горячая ванна
  • В день сдачи анализа необходимо сначала сдать кровь, а потом принимать привычные ежедневные лекарства
  • Если одним из исследуемых показателей является глюкоза, в день процедуры пациенту запрещается не только кушать, но также чистить зубы и жевать жвачку
  • Некоторые лекарственные препараты необходимо отменить заблаговременно (за одну-две недели) до сдачи анализов, например, статины при диагностике холестерина. Такие решения принимаются на усмотрение врача

Норма показателей

Все процессы в организме человека представляют собой биохимические реакции. На скорость их протекания и полученный результат влияет множество факторов — внешняя среда, функционирование других систем органов. Нормы, которые приводятся как не патологические результаты, представляют собой усредненные значения, которые были получены при изучении влияния наиболее стандартных факторов. К ним относятся забор крови на голодный желудок, пациент в состоянии покоя, отсутствие активности пищеварительной системы и некоторые другие. Хорошим показателем считается не конкретная цифра, а результат, попадающий в определенный диапазон.

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Количество веществ в крови у взрослых было выявлено опытным путем с широкой выборкой статистических данных при исследовании здоровых людей и лиц с патологиями. Перед интерпретацией результатов необходимо учитывать индивидуальные особенности каждого конкретного пациента, где важное значение имеет возраст, пол, сопутствующие заболевания, генетическая предрасположенность, профессиональная деятельность, наличие беременности и другие состояния. Окончательный диагноз ставится не только по набору цифр в полученной таблице из лаборатории, а после оценки общего анамнеза, картины крови и результатов дополнительных исследований.

Таблица расшифровки у взрослых и детей

В таблицах ниже приведены средние нормы показателей биохимического анализа крови у взрослых.

Показатель Ед. измерения Нормы для взрослого
Общий белок г/л 64-86
Альбумин г/л 35-50
Трансферрин г/л 2-4
Ферритин Мкг/л 20-250 (мужч.), 10-120 (женщ).
Билирубин общий/непрямой/прямой Мкмоль/л 8,6-20,5/0-4,5/0-15,6
Общий глобулин % 40-60
Ревматоидный фактор Ед/мл 0-10
Глюкоза Ммоль/л 3,3-5,5
Креатинин Мкмоль/л 62-100 (мужч.), 50-100 (женщ.)
Мочевина Ммоль/л 2,2-6,7 (женщ.), 3,8-7,3 (мужч.).

Средние нормы показателей биохимического анализа крови у детей.

Показатель Ед. измерения Нормы для детей до года Нормы для детей от года
Общий белок г/л 45-73 56-82
Альбумин г/л 30-50 37-55
Трансферрин г/л 2,03-3,6 2,03-3,6
Ферритин Мкг/л 25-600 30-140
Билирубин общий/непрямой/прямой Мкмоль/л 8,5-21,4/2,5-17,3/0,83-3,4/ 8,5-21,4/2,5/17,3/0,83-3,4/
Общий глобулин % 25-35 25-35
Ревматоидный фактор Ед/мл
Глюкоза Ммоль/л 1,7-6,1 3,3-6,1
Креатинин Мкмоль/л 35-110 35-110
Мочевина Ммоль/л 2,5-5,8 4,3-7,3

Общий белок сыворотки крови, фракции общего белка

Синтез белков и его фракций происходит у человека в печени. По количеству протеинов и общего белка можно судить о работоспособности этого органа. Пониженный показатель свидетельствует о заболеваниях печени, наличии воспалительных процессов, интоксикации, кровопотерях. Подобное состояние может наблюдаться при глистных инвазиях, низкопротеиновой диете, длительном лечении глюкокортикоидами.

Снижение уровня альбумина как белковой фракции часто является признаком почечной или печеночной недостаточности, активного тканевого распада, истощения. Недостаток белков особенно опасен в детском возрасте, так как приводит к нарушению роста организма и работы иммунной системы. Повышение показателей является одним из симптомов аутоиммунных заболеваний, обезвоживания, обширных ожогов, инфекционных процессов.

Уровень азотистого обмена

Многие биохимические реакции заканчиваются образованием азотистых продуктов. Их концентрация в организме также повышается при распаде тканей. Такие соединения являются токсичными для организма и в норме выводятся почками. Повышение концентрации азотистых продуктов свидетельствует о нарушении работы печени или ухудшении функции выделительной системы. Снижение их количества наблюдается при полиурии, нарушении процессов метаболизма, голодании, гипотиреозе.

Мочевина

Образуется в процессе метаболизма белков, выводится почками. Повышение концентрации этого соединения в крови свидетельствует о нарушении выделительной функции. Временное увеличение концентрации может наблюдаться при чрезмерном содержании белка в пище, а незначительное снижение – во время беременности.

Креатинин

Определение концентрации креатинина является одним из основных критериев для оценки работы почек. Вещество образуется в мышцах, выделяется в кровь, а затем выводится почками. Нормальная концентрация для конкретного человека зависит от его мышечной массы. Показатель является достаточно постоянным и его колебания в норме незначительны. Высокие значения наблюдаются при патологиях почек, заболеваниях щитовидной железы.

Мочевая кислота

Представляет собой один из конечных продуктов распада белков. Повышение концентрации этого продукта в крови является признаком нарушения выделительной функции и может наблюдаться при мочекаменной болезни, почечной недостаточности. Высокий уровень мочевой кислоты – один из основных симптомов подагры. Временное повышение возникает у спортсменов после интенсивных тренировок, а также при употреблении продуктов, богатых пуриновыми соединениями.

Глюкоза

Глюкоза – один из важнейших углеводов для организма человека. Она необходима для получения энергии, которую используют все клетки и ткани. Поступает глюкоза из пищи, а затем попадает в печень и утилизируется. Там же происходит ее накопление в виде гликогена. Процесс контролируется инсулином и глюкагоном – гомонами, благодаря которым концентрация глюкозы в крови поддерживается стабильной. Определение этого показателя является основным в диагностике сахарного диабета и оценки эффективности его лечения.

Гипогликемия

Патологическое состояние, при котором уровень глюкозы становится ниже нормы. Характеризуется набором определенных симптомов:

  • головокружение
  • нарушение координации
  • расстройство дыхания и кровообращения
  • повышенная тревожность и агрессивность
  • гипертонус мышц, тремор рук
  • чувство голода
  • слабость, тошнота, рвота

Гипогликемия может быть вызвана причинами двух типов:

  1. Физиологические – диета, голодание, интенсивные физические нагрузки, стресс, обезвоживание.
  2. Патологические – чрезмерная выработка инсулина, передозировка сахароснижающими препаратами, заболевания печени, эндокринные заболевания, нарушение всасывания углеводов.

Гипогликемия является очень опасной и при отсутствии своевременной помощи может привести к летальному исходу. В большинстве случаев, состояние легко корректируется приемом глюкозы в таблетках, сладкого чая, банана или конфеты. У детей гипогликемия может быть вызвана стрессами, несбалансированным питанием, физическими нагрузками. Ее появление объясняется несовершенством механизма накопления гликогена в печени. Последствиями гипогликемии может быть нарушение умственного и физического развития, ангиопатии, гипогликемическая кома, отмирание клеток головного мозга.

Гипергликемия

Так называется состояние, при котором концентрация глюкозы превышает верхний предел нормы. Основной причиной выступает сахарный диабет, при котором нарушена выработка инсулина – гормона, утилизирующего глюкозу в организме человека.

Временное повышение уровня глюкозы может наблюдаться при:

  • чрезмерном употреблении углеводов с пищей
  • приеме лекарственных препаратов, способствующих развитию гипергликемии – бета-блокаторы, диуретики, антидепрессанты и другие
  • острой стрессовой ситуации
  • инфекционно-воспалительном процессе

Гипергликемия не менее опасна для человека, чем гипогликемия. У здоровых людей уровень глюкозы незначительно колеблется в течение дня, но регулируется гормонами. При патологическом состоянии возникает стабильное повышение уровня глюкозы, что приводит к следующим симптомам:

  • неутолимая жажда
  • головные боли
  • сильная слабость, нарушение общего состояния и жизнедеятельности
  • тошнота
  • учащенное сердцебиение
  • холодная и сухая кожа, зуд
  • частое мочеиспускание
  • запах ацетона
  • снижение АД

При отсутствии своевременной помощи гипергликемия может закончиться комой.

Нарушение пигментного обмена в организме

Некоторые белки в организме человека соединены с атомом металла, что придает им особое окрашивание. При распаде таких соединений конечным продуктом является билирубин, концентрация которого является важным диагностическим показателем. Свободный билирубин является токсичным для организма, поэтому он быстро нейтрализуется белками и превращается в связанную форму. Нарушение этого процесса наблюдается при заболеваниях гепатобилиарного аппарата и выявляется в анализе крови как повышенное содержание свободного билирубина. Основное проявление патологии – желтушность и зуд кожи тела.

Липидный обмен или показатели холестерина

Липиды являются основным структурным компонентом клеточных мембран, а также источниками синтеза гормонов, витаминов и желчи. В крови находится несколько видов липидов, которые принимают участие в транспорте холестерина по крови и тканям организма. Холестерин вырабатывается в организме человека, а также поступает извне с пищей. При нарушении липидного обмена уровень этого соединения в крови увеличивается, из-за чего холестерин выпадает в осадок и накапливается в просвете сосудов. Такое состояние опасно ухудшением кровообращения в проблемной области, а также полной закупоркой сосуда в будущем.

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Ферменты крови

В биохимическом анализе также определяются особые белки, которые способствуют ускорению реакций в организме. Они находятся в клетках внутренних органов, поэтому повышение концентрации этих соединений в крови свидетельствует о разрушении клеток и структурном поражении.

Аспартатаминотрансфераза (АСАТ) и аланинаминотрансфераза

Эти соединения находятся в клетках печени, мышцах и миокарде. В зависимости от тяжести поражения этих органов, концентрация ферментов может повышаться в 1,5-10 раз. Такое состояние наблюдается при интоксикациях, опухолях, вирусных гепатитах, инфаркте.

Щелочная фосфатаза

Повышение концентрации этого фермента возникает при разрушении костной ткани (заживлении переломов, остеопорозе), гепатитах, миеломной болезни, токсических поражениях печени.

Гаммаглутамилтрансфераза

Этот фермент участвует в жировом обмене. Содержится в клетках печени, предстательной и поджелудочной железы, почек. Концентрация фермента увеличивается при сахарном диабете, разрушении тканей органов, где он ГГТ расположена, алкогольной интоксикации.

Креатинкиназа

Фермент катализирует превращение креатина и образование энергии в клетке. В больших концентрациях она находится в мышцах, миокарде и головном мозге. Повышение концентрации наблюдается при деструктивных процессах этих локализаций. Проблемы с мышечной тканью могут быть спровоцированы длительным сдавливанием, гангреной, миастенией. Разрушение миокарда происходит при миокардите, длительном лечении стероидными гормонами, остом инфаркте. Высвобождение креатинкиназы головного мозга наблюдается при шизофрении, энцефалите.

Альфа-амилаза

Этот фермент один из первых принимает участие в цепочке реакций пищеварения. Он помогает расщеплять сложные углеводы на более простые и начинает работать сразу после попадания пищи в ротовую полость. Альфа-амилазу вырабатывают слюнные железы и поджелудочная железа. Диагностическое значение имеет изменение значения как в сторону увеличения, так и снижения. Повышение уровня фермента возникает при панкреатите, раке поджелудочной, почечной недостаточности, вирусном гепатите. Снижение провоцируют такие заболевания, как тиреотоксикоз, инфаркт миокарда, некроз поджелудочной.

Электролиты крови – что это?

Кроме форменных элементов в крови содержатся электролиты – ионы, которые поддерживают гомеостаз и обеспечивают протекание всех химических реакций. Наиболее важное значение имеют концентрации калия и натрия.

Калий

Выполняет множество важных функций в организме человека, которые нарушаются при изменении концентрации этого микроэлемента. Калий способствует проведению электрических импульсов в миокарде, мышцах и сосудах. Гиперкалиемия приводит к следующим симптомам:

  • падение АД
  • головокружение
  • аритмия, замедление пульса
  • нарушение чувствительности

При выраженном снижении количества калия в крови наблюдается сердечная и мышечная слабость, затруднение дыхания, тошнота и рвота.

Натрий

Натрий не участвует в обменен веществ, однако обеспечивает стабильность давления внутри клетки и вне ее. Поддержание осмотического давления – основная функция этого микроэлемента. Повышение концентрации натрия в крови может наблюдаться при ухудшении его выведения из организма или нарушении работы альдостероновой системы, которая контролирует этот процесс.

Ревмопробы

Проводятся с целью диагностировать воспалительные заболевания соединительной ткани. На них будет указывать повышение концентрации следующих показателей:

  • С-реактивный белок (повышается в острой фазе, а также при некротических процессах)
  • Антистрептолизин (свидетельствует о стрептококковой инфекции)
  • Ревматоидный фактор (аутоантитела, которые говорят о высокой вероятности ревматоидного артрита, дерматомиозита и других состояний)

Заключение

Биохимический анализ крови — быстрый и надежный способ оценить качество работы целого организма. В комплексный анализ входят основные показатели по функционированию каждого органа или важнейшие маркеры патологий. Биохимию часто назначают, когда предварительных диагнозов может быть несколько или врачу не ясна этиология появившихся симптомов. Уже через пару дней после взятия биоматериала пациент может получить развернутую картину, которая описывает, где в организме наблюдается сбой. Основные рекомендации при этом – соблюдать правила подготовки к анализу и не пытаться интерпретировать полученные результаты самостоятельно.

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Практически ни одно медицинское обследование организма не обходится без лабораторных анализов. При всей своей простоте они способны дать врачу общую картину состояния пациента и указать на возможные патологии органов. Мы рассмотрим процесс подготовки к биохимическим исследованиям мочи и крови, укажем, какие показатели исследуют, и расскажем, что означают отклонения от нормальных значений.

Особенности проведения биохимического анализа

Поскольку кровь циркулирует во всех органах человеческого тела, ее химический состав может меняться — в зависимости от наличия патологий в одном или нескольких из них. Поэтому биохимический анализ крови — наиболее распространенное исследование, которое назначают при жалобах пациента на самочувствие и подозрениях на нарушение функции почек, печени, щитовидной железы.

Забор биоматериала осуществляется утром, с 8 до 11 часов, обязательно — на голодный желудок, но при этом время голодания не должно превышать 14 часов. Для анализа у пациента берут венозную кровь в объеме около пяти–восьми миллилитров.

Биохимический анализ мочи также является одним из базовых вспомогательных исследований: он позволяет выявить не только наличие патологий мочеполовой системы, но и получить сведения о состоянии желчевыводящих путей и работе многих систем организма. Анализ назначают в период беременности, при сахарном диабете и подозрениях на заболевания почек.

Забор биоматериала проводят в домашних условиях, в течение суток, начиная с раннего утра, собирая мочу в емкость. Важные правила при сборе:

  • использовать только стерильную емкость;
  • первую утреннюю порцию собирать не нужно;
  • перед мочеиспусканием провести гигиенические процедуры;
  • между походами в туалет и до передачи в клинику мочу необходимо хранить в холодильнике (не более суток).

После сбора всего биоматериала за сутки, его перемешивают, измеряют объем, переливают немного (до 50 мл) в специальную маленькую баночку, на которой указывают общее количество мочи за сутки, рост и вес пациента. Затем емкость можно передать в лабораторию.

Расшифровка биохимического анализа крови

Результатом анализа является выданное заключение о содержании химических веществ и биологических агентов в крови. Как правило, документ представляет собой таблицу, в первой колонке которой указано название показателя, во второй — выявленное значение, в третьей — диапазон нормы. По этой таблице специалист оценивает отклонения от нормы и на основании этого может судить о нарушениях в работе органов.

Показатели биохимического анализа и их нормативные величины

Диапазон нормальных значений для того или иного показателя может меняться в зависимости от клиники и лаборатории, и это не является ошибкой. Окончательное решение, считать ли значение превышенным, нормальным или пониженным, принимает врач на основе анамнеза.

В нижеприведенной таблице можно ознакомиться с примерными показателями нормы содержания веществ при биохимическом анализе крови:

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измерения показателей

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