Лекарства Пентоксифиллин или Трентал являются аналогами друг друга. Они отличаются лишь стоимостью и компанией-производителем.
Сходства составов Пентоксифиллина и Трентала
Препараты содержат в себе одинаковый активный ингредиент — пентоксифиллин. Это вещество обладает следующими преимуществами:
- выраженное действие;
- безопасность;
- повышение пластичности эритроцитов;
- использование в лечении артрита, артроза, варикоза и иных патологий;
- высокие показатели биодоступности;
- спокойная переносимость.
Лекарства Пентоксифиллин или Трентал являются аналогами друг друга.
Медикаменты применяются для длительной терапии. Они обладают высоким уровнем эффективности в лечении сосудистых патологий и нарушения кровообращения. Кроме того, ими можно пользоваться для предупреждения развития инфаркта миокарда за счет улучшения состояния сосудистой оболочки. Трентал и Пентоксифиллин обладают одинаковыми противопоказаниями:
- вынашивание плода;
- кормление грудью;
- выраженная гипотония;
- нарушение частоты сердечных сокращений;
- заболевания печени;
- кровоизлияния в глазных яблоках;
- атеросклероз;
- кровотечение.
Лекарства способствуют ликвидации трофических состояний в сосудистом русле и улучшению процессов микроциркуляции крови. По сравнению с местными средствами таблетированные лекарственные формы можно использовать при поражении кожных покровов. Оба препарата ускоряют общее восстановление. Однако их нельзя давать пациентам, которые недавно перенесли инфаркт. В таком случае при болезнях сосудов назначаются другие медикаменты.
Пентоксифиллин применяют при лечении сосудистых патологий.
В чем разница между Пентоксифиллином и Тренталом
Препараты обладают множеством терапевтических свойств, однако у них есть ряд несущественных различий, которые связаны с производителем и ценой.
Кроме того, Пентоксифиллин также выпускается в виде раствора. У Трентала отсутствует подобная форма выпуска. Это дает возможность более удобно и точно подбирать рекомендованные врачом дозировки. По другим параметрам лекарства одинаковые. Несмотря на безрецептурный отпуск, пользоваться медикаментами рекомендуется по согласованию с лечащим врачом.
Упаковка чешского производства из 20 таблеток с дозировкой 400 мг стоит около 280 руб. Пентоксифиллин с обозначением «СЗ» обладает пролонгированным высвобождением активного вещества. Этот препарат производится российской компанией. Он продается по цене от 240 руб. за 20 таблеток с дозировкой 400 мг. Таблетки по 100 мг действующего вещества стоят от 235 руб. за 60 шт. Растворимая форма медикамента выпускается в ампулах объемом 5 мл. Стоимость пачки из 10 ампул — 50 руб.
Упаковка из 60 таблеток Трентала 400 мг французского производства стоит 1400 руб. Индийская версия медикамента продается по цене от 650 руб. за 20 таблеток.
Трентал применяют для предупреждения развития инфаркта миокарда.
Что лучше
Выбирая между Тренталом и Пентоксифиллином, необходимо посоветоваться с доктором, который подберет наиболее подходящую лекарственную форму и режим дозирования. Эксперты рекомендуют отдавать предпочтение оригинальному фармацевтическому продукту, т.к. безопасность и эффективность его применения подтверждается сертификатами и результатом клинических испытаний.
Особую осторожность при выборе препарата следует проявить пациентам с запущенными сосудистыми патологиями и гипоксическими нарушениями.
Отзывы врачей о Пентоксифиллине и Трентале
Святослав Пчелинцев (флеболог), 40 лет, Брянск
Эти медикаментозные средства эффективны в терапии сосудистых нарушений у пациентов с повышенным риском развития тромбообразования и патологий кровообращения. Для достижения наибольшего эффекта их прием должен сопровождаться применением местных гелей и мазей. Пациенты хорошо переносят препараты.
Артур Моисеев (флеболог), 37 лет, Владивосток
Я часто принимаю пациентов, которые жалуются на отеки, венозную сеточку и болезненные ощущения в сосудах. В таких ситуациях я рекомендую пользоваться Тренталом или Пентоксифиллином. Лекарства имеют практически одинаковое действие и дают возможность оперативно устранить отрицательные проявления сосудистых болезней.
Несмотря на относительную безопасность этих средств, перед их приемом желательно посетить доктора и пройти ряд обследований на предмет наличия противопоказаний. Это позволит избежать побочных действий.
Николай Бровкин (флеболог), 42 года, Смоленск
Пентоксифиллин при нарушениях микроциркуляционных процессов и недостаточности венозных сосудов я назначаю чаще, чем Трентал. Терапия с его помощью длится долго, поэтому лучше отдавать предпочтение более дешевому варианту.
Отзывы пациентов
Сергей Лаврентьев, 49 лет, Балашиха
Когда я лечил тромбофлебит, доктор выписал Трентал. Пользовался лекарством в рекомендованных дозах. В первые 2 дня у меня появилась легкая тошнота, но в течение всего дальнейшего лечения никаких проблем больше не возникало. Медикамент эффективный, с его помощью я смог полностью излечиться. После завершения лечебного курса я стал себя чувствовать гораздо лучше.
Ника Саблина, 53 года, Воронеж
Уже около 5 лет страдают варикозом. В первое время патология не давала о себе знать. Однако со временем появились сосудистые звездочки, тяжесть в ногах и отечность. Дискомфорт постепенно усиливался. В результате я решила обратиться к знакомому флебологу, чтобы он подобрал для меня эффективные и безопасные средства. Врач выписал Пентоксифиллин. Купила его в аптеке. Пользоваться средством стала регулярно в течение 4 недель. В этот период ни разу не пропускала прием и соблюдала указанные специалистом дозы. После курсового применения неприятные проявления исчезли.
Михаил Смагин 50 лет, Сергиев Посад
Лечил варикоз кремами. Полтора месяца назад доктор посоветовал воспользоваться таблетками Трентал. В результате я прошел полный курс их приема. За это время у меня исчезли все отрицательные признаки сосудистой патологии, включая боли и отечность.Хорошее лекарство. Недавно я даже посоветовал его своему брату, который столкнулся с аналогичной проблемой.
Разные торговые названия медикаментов часто вызывают вопросы у больных. Выясняя, что выбрать для лечения — Пентоксифиллин или Трентал — они должны помнить, что это препараты-аналоги, разница состоит лишь в производителе и цене фармацевтических средств.
Сходства составов Пентоксифиллина и Трентала
Оба препарата имеют одно и то же действующее вещество — пентоксифиллин.
Достоинствами как Трентала, так и Пентоксифиллина являются:
- безопасность;
- эффективность;
- улучшение пластических свойств эритроцитов;
- применение для терапии сосудистых заболеваний;
- биодоступность;
- хорошая переносимость.
Препараты используются для продолжительного лечения.
Оба средства отличаются высокой эффективностью при терапии нарушений сосудистой оболочки, расстройства кровообращения. Эти медикаменты применяются для лечения артрита и артроза. Они проявляют эффективность в устранении заболеваний сосудов, используются для терапии последствий инсульта, в целях профилактики при риске развития инфаркта. У обоих препаратов одни и те же противопоказания:
- пониженное давление;
- беременность;
- лактация;
- кровотечение;
- нарушения сердечного ритма;
- заболевания печени;
- атеросклероз;
- глазные кровоизлияния.
Препараты используются для устранения трофических изменений сосудистого русла. В отличие от средств местного применения, таблетки этих фармакологических средств можно применять для лечения даже при повреждениях кожи. Оба медикамента назначают в период восстановления организма. Кроме того, и Пентоксифилин, и Трентал нельзя использовать для лечения больных, которые только что перенесли инфаркт.
В чем разница между Пентоксифиллином и Тренталом
Эти лекарства характеризуются большим количеством общих свойств, но есть и несколько незначительных различий.
Так, если сравнивать рассматриваемые медикаменты, то окажется что их отличие друг от друга состоит только в стоимости и изготовителе.
Пентоксифиллин имеет готовую форму раствора, которой нет у Трентала. Благодаря этому его использование становится более удобным. Во всем остальном медикаменты одинаковые. Назначить средство должен врач, он выбирает форму лекарства, дозировку.
Пентоксифиллин в форме таблеток в дозировке 400 мг 20 шт. производства Чехии стоит 286 руб. Пентоксифиллин-C3 в таблетках с пролонгированным высвобождением, покрытых оболочкой, в дозировке 400 мг в количестве 20 шт. производства России можно приобрести по стоимости 246 руб. Пентоксифиллин в таблетках по 100 мг в количестве 60 шт. производства России стоит 234 руб. Пентоксифиллин в форме раствора для инъекций в ампулах по 5 мл количеством 10 шт. продается по цене 48 руб.
Трентал в таблетках по 400 мг 60 шт. производства Франции стоит 1408 руб. Трентал в таблетках по 400 мг 20 шт. производства Индии имеет цену 651 руб.
Что лучше
Выбирая Трентал или Пентоксифиллин, надо проконсультироваться у врача, который назначит форму препарата, подберет концентрацию и дозу лекарственного средства. Если больной не знает, что лучше выбрать для лечения патологии кровообращения, то нужно придерживаться таких правил: следует выбирать оригинальный продукт, одобренный организацией контроля качества медикаментов.
Особенно тщательно требуется выбирать медикамент пациентам с тяжелыми гипоксическими патологиями и болезнями сосудов в запущенной стадии.
Следует учитывать результаты клинических испытаний лекарственных средств. Если больной не может купить дорогое фармацевтическое средство, нужно посоветоваться с врачом для того, чтобы подобрать эффективный и недорогой аналог.
Отзывы врачей о Пентоксифиллине и Трентале
Пасечников Дмитрий Васильевич, врач-флеболог
Трентал и Пентоксифиллин показывают высокую эффективность при лечении сосудов у людей с нарушениями кровообращения и угрозой образования тромбов. Эти средства можно применять в сочетании с мазями и гелями для местного использования. Больные хорошо переносят оба лекарства.
Озерский Сергей Константинович, флеболог
На прием часто приходят больные с жалобами на боли в сосудах, отечность, венозную сетку. Для лечения патологии сосудов часто назначаю Трентал или Пентоксифиллин. Эти средства обладают высокой эффективностью и помогают быстро справиться с симптомами варикозных заболеваний.
Сергеев Василий Николаевич, врач-флеболог
Для лечения венозной недостаточности и нарушений микроциркуляции крови чаще назначаем Пентоксифиллин, чем Трентал, потому что он дешевле. Лечение продолжается достаточно долго, и, чтобы не тратить много средств на медикаменты, можно выбрать более дешевый препарат, который по своему качеству и эффективности ничем не уступает дорогому.
Отзывы пациентов
Виктор Иванович, 52 года
Врач назначил Трентал от тромбофлебита. Принимал лекарство в дозировках, рекомендуемых врачом. Сначала появилась легкая тошнота, но через несколько дней все прошло. Препарат достаточно эффективный, помог при лечении сосудов. После окончания курса улучшились общее самочувствие и работоспособность.
Вероника Николаевна, 49 лет
Несколько лет страдаю варикозным расширением вен. Появились сосудистые звездочки, к вечеру бывает тяжесть в ногах, появляются отеки, болезненность. Лечилась мазями, наружными средствами и народными способами. Доктор назначил для терапии препарат Пентоксифиллин. Регулярно принимала это средство в течение месяца. По окончании курса лечения состояние намного улучшилось, прошли отеки и тяжесть в ногах, исчезли боли.
Михаил Сергеевич, 50 лет
Страдаю варикозным заболеванием сосудов. Лечился мазями и народными средствами. Недавно врач порекомендовал пить таблетки Трентал, прошел курс лечения описываемым препаратом. После этого симптомы болезни прошли, исчезли отеки и сосудистые звездочки, прекратились дискомфортные ощущения. Это отличное средство от варикоза и аналогичных проблем, рекомендую его всем больным сосудистыми патологиями.
При лечении различных сосудистых заболеваний, а также при проблемах с кровообращением у пациентов, врачи довольно часто назначают фармпрепараты на основе пентоксифиллина. Это вещество является основным действующим компонентом препарата Трентал.
У этого препарата существует множество аналогов по более низкой цене. Но так ли они хороши — разберем в этой статье.
Что такое трентал
Трентал – оригинальный препарат, разработанный, запатентованный и производимый фирмой Санофи-Авентис.
Компания вложила огромные средства в разработку формулы и технологического процесса, клинические исследования, изучение совместимости с другими препаратами и добилась наилучших результатов среди препаратов этого класса.
Разумеется, пользуясь своим преимущественным положением на рынке, компания назначает высокую цену за свой препарат, чтобы вернуть сделанные инвестиции и получить прибыль.
Другие производители, в соответствии с лицензионными соглашениями использующие результаты исследований Санофи-Авентис, не стоят перед необходимостью возврата средств, и выпускают на рынок аналогичные по своему составу и действию препараты по существенно более низкой цене.
Это вазодилатирующее средство, улучшающее циркуляцию в малых кровеносных сосудах, ангиопротектор, производное ксантина. Трентал возвращает прежний уровень пластичности эритроцитов, улучшает их способность проникать в сильно суженые сосуды.
Препарат разжижает кровь и восстанавливает нормальный уровень ее микроциркуляции в зонах ослабленного кровообращения.
Действующим веществом является пентоксифиллин.
Химическая формула пентоксифиллина
Трентал является препаратом замедленного действия (ретард), высвобождение действующего вещества происходит постепенно, в течение нескольких часов.
По сравнению со всеми аналогами, оригинал обладает максимальной лечебной эффективностью при равной дозировке, лучшей совместимостью с другими препаратами и минимальной частотой возникновения побочных эффектов. Это обуславливается фирменной запатентованной технологией производства и очистки лекарственного средства.
Фармакологическое действие
Пентоксифиллин увеличивает просвет кровеносных сосудов, расслабляя их гладкие мышцы. Незначительно расширяются и коронарные сосуды
Применение Трентала приводит к улучшению состояния пациента и при ослаблении кровотока мозга.
В случае проблем с периферическими артериями применение Трентала приводит к облегчению ходьбы, увеличению расстояния, проходимого за день без боли, снятию судорог, возникающих ночью в икрах.
Состав
1 таблетка содержит:
Активное вещество: пентоксифиллина 100 мг.
Форма выпуска:
- таблетки, в упаковках по 60 штук.
- ампулы, по 100 мг
Важно. Выбор лекарства для внутримышечного или внутривенного введения- целиком прерогатива врача.
Когда применяют:
перемежающаяся хромота, вызванная замедлением кровотока в периферических кровеносных сосудах;
- диабетическая ангиопатия;
- язвы голеней, гангрена;
- проблемы с концентрацией внимания, головокружения, ослабление памяти вследствие замедления кровотока мозга;
- ишемические и постинсультные состояния;
- затруднеие кровотока в сетчатке и сосудистой оболочке глаза;
- отосклероз;
- снижение слуха вследствие заболеваний сосудов внутреннего уха.
Противопоказания:
- острый инфаркт миокарда;
- сильное кровотечение;
- кровоизлияние в мозг;
- сильное кровоизлияние в сетчатку глаза;
- беременность, кормление грудью;
- не назначается детям до 18 лет.
Препараты-аналоги трентала
Все аналоги, или дженерики трентала обладают аналогичным фармакологическим действием, практически совпадающими списками показаний и противопоказаний и весьма близкими перечнями побочных эффектов.
Все упомянутые препараты обладают способностью улучшать как кровообращение в небольших кровеносных сосудах, так обеспечение тканей кислородом. Также все они противопоказаны беременным и кормящим матерям, а также детям и лицам до 18 лет.
Все аналоги трентала стоят дешевле оригинала. Компании производители могут себе это позволить, поскольку для них нет необходимости в возврате инвестиций на фундаментальные исследования, разработку формулы, многолетние клинические исследования эффективности и безопасности средства, расходы на продвижение препарата на рынке, совместимости средства с другими лекарствами, исследование побочных эффектов, процедуры по патентованию и правовой защите.
Как правило, в процессе разработки и исследования создается и проверяется несколько технологий получения действующего вещества. Наиболее эффективная и обладающая наименьшими побочными эффектами из них регистрируется в качестве оригинального препарата.
Остальные выводятся производителем оригинала на лицензионный рынок, где и приобретаются производителями аналогов.
Безусловно, все они обязаны в точности соблюдать правила производства и технологию. В развитых странах, контроль за соблюдением технологии и правил производства лекарственных средств осуществляется весьма строго как государственными чиновниками, так и профессиональными медицинскими и фармакологическими объединениями. В развивающихся странах такой контроль существенно слабее из-за недостаточно зрелости профессиональных объединений и коррупции среди чиновников.
Агапурин (Чехия)
Форма выпуска-таблетки 100 мг и ампулы 100 мг. По сравнению с другими иностранными аналогами отмечается низкая частота побочных эффектов. В последнее время применяется для лечения легочных заболеваний.
Вазонит (Австрия)
Так же, как и трентал, обладает пролонгированным действием, осуществляя медленное высвобождение действующего вещества.
Чаще назначается при варикозе, отличается высокой дозировкой — 600 мг. выпускается только в таблетках
Вопрос что лучше вазонит или трентал в аспекте эффективности решается в пользу Трентала, в аспекте цены — в пользу Вазонита.
Пентилин (Словения)
Чаще назначается при перемежающейся хромоте, проявляет обезболивающее действие.
Пентоксифиллин
Чистое действующее вещество с более быстрым, и, соответственно, менее продолжительным действием.
Пациенты и врачи отмечают сопоставимую эффективность по сравнению с более дорогими заменителями трентала , однако чаще обращают внимание на возникающие побочные эффекты. Также отзывы показывают большее число проблем совместимости с другими лекарственными средствами.
Среди потребителей дилемма о том, что лучше: трентал или пентоксифиллин , согласно отзывам , часто решается в пользу последнего исходя их финансовых соображений.
Отвечая на вопрос, что лучше: трентал или пентоксифиллин или другой аналог-прежде всего необходимо оценить общее состояние больного, есть ли сопутствующие заболевания.
Если состояние неважное, к тому же осложненное сопутствующими заболеваниями, такими, например, как диабет или гипертензия-лучше выбрать оригинальный Трентал, у которого ниже риск возникновения побочных эффектов и лучше совместимость с другими препаратами.
Часто в качестве первичного курса назначается импортный препарат, по достижении терапевтического эффекта врач принимает решение: переходить для дальнейшего, поддерживающего курса на дешевый аналог или нет.
С особой осторожностью нужно назначать дозу при диабете.
Необходимо регулярно, несколько раз в день, контролировать артериальное давление.
В случае ухудшения состояния пациента или проявления побочных эффектов выбор «пентоксифиллин или трентал» не стоит — следует немедленно вернуться к Тренталу.
Подбор препарата, лекарственную форму и дозировку должен осуществлять врач. Только он сможет квалифицированно оценить всю совокупность влияющих на выбор факторов, таких как:
- состояние пациента
- принесённые и сопутствующие заболевания
- совместно назначаемые препараты
- реакция пациента на прием препарата.
И решить, уместна в каждом конкретном случае та или иная замена.
Заключение
Оригинальный препарат Трентал обладает наилучшим терапевтическим действием, наименьшим риском возникновения побочных эффектов и наибольшей совместимостью с другими лекарствами.
Его аналоги существенно (до нескольких раз) дешевле и практически так же эффективны, но их лучше применять при неосложненных случаях заболеваний, вне острых состояний и при отсутствии тяжелых сопутствующих диагнозов, а также для длительных курсов поддерживающего лечения. Конечное слово в любом случае остается за лечащим врачом.
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